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Output includes all games that meet at least one of the following criteria: 300+ yards passing, 100+ yards rushing, 100+ yards receiving, or 4+ passing touchdowns.
| Passing | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rk | Year | G# | Date | Age | Tm | Opp | Result | Cmp | Att | Yds | TD | Int | |||||
| 1 | 1999 | 19 | 2000-01-30 | 28-222 | STL | N | TEN | W 23-16 | 24 | 45 | 53.3% | 414 | 2 | 0 | 99.7 | 9.20 | 10.09 |
| Passing | |||||||||||||||||
| Rk | Year | G# | Date | Age | Tm | Opp | Result | Cmp | Att | Yds | TD | Int | |||||
| 2 | 2000 | 1 | 2000-09-04 | 29-074 | STL | DEN | W 41-36 | 25 | 35 | 71.4% | 441 | 3 | 3 | 106.5 | 12.60 | 10.46 | |
| 3 | 2000 | 2 | 2000-09-10 | 29-080 | STL | @ | SEA | W 37-34 | 35 | 47 | 74.5% | 386 | 1 | 1 | 96.6 | 8.21 | 7.68 |
| Passing | |||||||||||||||||
| Rk | Year | G# | Date | Age | Tm | Opp | Result | Cmp | Att | Yds | TD | Int | |||||
| 4 | 2001 | 1 | 2001-09-09 | 30-079 | STL | @ | PHI | W 20-17 | 28 | 42 | 66.7% | 308 | 1 | 2 | 76.3 | 7.33 | 5.67 |
| 5 | 2001 | 5 | 2001-10-14 | 30-114 | STL | NYG | W 15-14 | 28 | 46 | 60.9% | 316 | 0 | 1 | 72.4 | 6.87 | 5.89 | |
| Passing | |||||||||||||||||
| Rk | Year | G# | Date | Age | Tm | Opp | Result | Cmp | Att | Yds | TD | Int | |||||
| 6 | 2005 | 12 | 2005-12-04 | 34-165 | ARI | @ | SFO | W 17-10 | 29 | 45 | 64.4% | 354 | 1 | 2 | 77.5 | 7.87 | 6.31 |
| Passing | |||||||||||||||||
| Rk | Year | G# | Date | Age | Tm | Opp | Result | Cmp | Att | Yds | TD | Int | |||||
| 7 | 2007 | 15 | 2007-12-23 | 36-184 | ARI | ATL | W 30-27 | 35 | 52 | 67.3% | 369 | 3 | 0 | 107.0 | 7.10 | 8.25 | |
| Passing | |||||||||||||||||
| Rk | Year | G# | Date | Age | Tm | Opp | Result | Cmp | Att | Yds | TD | Int | |||||
| 8 | 2008 | 9 | 2008-11-10 | 37-141 | ARI | SFO | W 29-24 | 32 | 42 | 76.2% | 328 | 3 | 0 | 121.9 | 7.81 | 9.24 | |
| 9 | 2008 | 19 | 2009-01-18 | 37-210 | ARI | PHI | W 32-25 | 21 | 28 | 75.0% | 279 | 4 | 0 | 145.7 | 9.96 | 12.82 | |
| Passing | |||||||||||||||||
| Rk | Year | G# | Date | Age | Tm | Opp | Result | Cmp | Att | Yds | TD | Int | |||||
| 10 | 2009 | 4 | 2009-10-11 | 38-111 | ARI | HOU | W 28-21 | 26 | 38 | 68.4% | 302 | 2 | 0 | 109.8 | 7.95 | 9.00 | |
| 11 | 2009 | 9 | 2009-11-15 | 38-146 | ARI | SEA | W 31-20 | 29 | 38 | 76.3% | 340 | 2 | 0 | 120.5 | 8.95 | 10.00 | |
| 12 | 2009 | 17 | 2010-01-10 | 38-202 | ARI | GNB | W 51-45 | 29 | 33 | 87.9% | 379 | 5 | 0 | 154.1 | 11.48 | 14.52 | |