| Single-season | Passing | Rushing | Receiving | Returns | Kicking | Scoring | |
| Career | Passing | Rushing | Receiving | Returns | Kicking | Scoring | Defense |
| Rk | Year | Age | Tm | Pos | G | GS | Rec | Yds | TD | Lng | Fmb | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Andre Johnson | 2008*+ | 27 | HOU | WR | 16 | 16 | 115 | 1575 | 13.7 | 8 | 65 | 7.2 | 98.4 | 1 |
| 2 | Andre Johnson | 2006* | 25 | HOU | WR | 16 | 16 | 103 | 1147 | 11.1 | 5 | 53 | 6.4 | 71.7 | 1 |
| 3 | Andre Johnson | 2004* | 23 | HOU | WR | 16 | 16 | 79 | 1142 | 14.5 | 6 | 54 | 4.9 | 71.4 | 1 |
| 4 | Owen Daniels | 2008* | 26 | HOU | TE | 16 | 16 | 70 | 862 | 12.3 | 2 | 35 | 4.4 | 53.9 | 2 |
| 5 | Domanick Williams | 2004 | 24 | HOU | RB | 15 | 15 | 68 | 588 | 8.6 | 1 | 38 | 4.5 | 39.2 | 4 |
| 6 | Andre Johnson | 2003 | 22 | HOU | WR | 16 | 16 | 66 | 976 | 14.8 | 4 | 46 | 4.1 | 61.0 | 0 |
| 7 | Kevin Walter | 2007 | 26 | HOU | WR | 16 | 15 | 65 | 800 | 12.3 | 4 | 46 | 4.1 | 50.0 | 0 |
| 8 | Owen Daniels | 2007 | 25 | HOU | TE | 16 | 16 | 63 | 768 | 12.2 | 3 | 29 | 3.9 | 48.0 | 4 |
| 9 | Andre Johnson | 2005 | 24 | HOU | WR | 13 | 13 | 63 | 688 | 10.9 | 2 | 53 | 4.8 | 52.9 | 1 |
| 10 | Andre Johnson | 2007 | 26 | HOU | WR | 9 | 9 | 60 | 851 | 14.2 | 8 | 77 | 6.7 | 94.6 | 1 |
| 11 | Kevin Walter | 2008 | 27 | HOU | WR | 16 | 16 | 60 | 899 | 15.0 | 8 | 61 | 3.8 | 56.2 | 0 |
| 12 | Eric Moulds | 2006 | 33 | HOU | WR | 16 | 16 | 57 | 557 | 9.8 | 1 | 29 | 3.6 | 34.8 | 1 |
| 13 | Jabar Gaffney | 2005 | 25 | HOU | WR | 16 | 13 | 55 | 492 | 8.9 | 2 | 29 | 3.4 | 30.8 | 0 |
| 14 | Andre Johnson | 2009 | 28 | HOU | 9 | 54 | 800 | 14.8 | 4 | 72 | 6.0 | 88.9 | 0 | ||
| 15 | Billy Miller | 2002 | 25 | HOU | te | 16 | 7 | 51 | 613 | 12.0 | 3 | 42 | 3.2 | 38.3 | 0 |
| 16 | Steve Slaton | 2008 | 22 | HOU | RB | 16 | 15 | 50 | 377 | 7.5 | 1 | 46 | 3.1 | 23.6 | 3 |
| 17 | James Allen | 2002 | 27 | HOU | rb | 16 | 5 | 47 | 302 | 6.4 | 0 | 21 | 2.9 | 18.9 | 1 |
| 18 | Domanick Williams | 2003 | 23 | HOU | RB | 14 | 10 | 47 | 351 | 7.5 | 0 | 17 | 3.4 | 25.1 | 4 |
| 19 | Corey Bradford | 2002 | 27 | HOU | WR | 16 | 16 | 45 | 697 | 15.5 | 6 | 81 | 2.8 | 43.6 | 0 |
| 20 | Jabar Gaffney | 2004 | 24 | HOU | WR | 16 | 12 | 41 | 632 | 15.4 | 2 | 69 | 2.6 | 39.5 | 1 |
| 21 | Jabar Gaffney | 2002 | 22 | HOU | WR | 16 | 14 | 41 | 483 | 11.8 | 1 | 27 | 2.6 | 30.2 | 1 |
| 22 | Owen Daniels | 2009 | 27 | HOU | 8 | 40 | 519 | 13.0 | 5 | 44 | 5.0 | 64.9 | 1 | ||
| 23 | Billy Miller | 2003 | 26 | HOU | te | 16 | 6 | 40 | 355 | 8.9 | 3 | 25 | 2.5 | 22.2 | 0 |
| 24 | Domanick Williams | 2005 | 25 | HOU | RB | 11 | 11 | 39 | 337 | 8.6 | 4 | 33 | 3.5 | 30.6 | 2 |
| 25 | Corey Bradford | 2005 | 30 | HOU | wr | 16 | 6 | 34 | 436 | 12.8 | 5 | 50 | 2.1 | 27.3 | 0 |
| 26 | Owen Daniels | 2006 | 24 | HOU | TE | 14 | 12 | 34 | 352 | 10.4 | 5 | 33 | 2.4 | 25.1 | 0 |
| 27 | Jabar Gaffney | 2003 | 23 | HOU | WR | 16 | 11 | 34 | 402 | 11.8 | 2 | 33 | 2.1 | 25.1 | 0 |
| 28 | Andre' Davis | 2007 | 28 | HOU | wr | 14 | 8 | 33 | 583 | 17.7 | 3 | 53 | 2.4 | 41.6 | 1 |
| 29 | Wali Lundy | 2006 | 23 | HOU | RB | 14 | 8 | 33 | 204 | 6.2 | 0 | 15 | 2.4 | 14.6 | 1 |
| Rk | Year | Age | Tm | Pos | G | GS | Rec | Yds | TD | Lng | Fmb | ||||
| 30 | Steve Slaton | 2009 | 23 | HOU | 9 | 32 | 326 | 10.2 | 3 | 38 | 3.6 | 36.2 | 7 | ||
| 31 | Derick Armstrong | 2004 | 25 | HOU | 14 | 1 | 29 | 415 | 14.3 | 1 | 44 | 2.1 | 29.6 | 0 | |
| 32 | Corey Bradford | 2004 | 29 | HOU | WR | 15 | 10 | 27 | 399 | 14.8 | 3 | 47 | 1.8 | 26.6 | 0 |
| 33 | Kevin Walter | 2009 | 28 | HOU | 7 | 27 | 328 | 12.1 | 1 | 41 | 3.9 | 46.9 | 0 | ||
| 34 | Vonta Leach | 2007 | 26 | HOU | FB | 16 | 12 | 25 | 108 | 4.3 | 2 | 15 | 1.6 | 6.8 | 2 |
| 35 | Corey Bradford | 2003 | 28 | HOU | wr | 16 | 6 | 24 | 460 | 19.2 | 4 | 78 | 1.5 | 28.8 | 0 |
| 36 | Marcellus Rivers | 2005 | 27 | HOU | te | 16 | 5 | 24 | 168 | 7.0 | 0 | 20 | 1.5 | 10.5 | 0 |
| 37 | Jonathan Wells | 2005 | 26 | HOU | rb | 15 | 6 | 22 | 179 | 8.1 | 0 | 20 | 1.5 | 11.9 | 1 |
| 38 | JaJuan Dawson | 2002 | 25 | HOU | 14 | 2 | 21 | 286 | 13.6 | 0 | 28 | 1.5 | 20.4 | 1 | |
| 39 | David Anderson | 2008 | 25 | HOU | 16 | 1 | 19 | 241 | 12.7 | 2 | 65 | 1.2 | 15.1 | 0 | |
| 40 | David Anderson | 2009 | 26 | HOU | 9 | 18 | 180 | 10.0 | 0 | 27 | 2.0 | 20.0 | 0 | ||
| 41 | Jameel Cook | 2006 | 27 | HOU | FB | 11 | 6 | 18 | 107 | 5.9 | 0 | 15 | 1.6 | 9.7 | 2 |
| 42 | Ron Dayne | 2007 | 29 | HOU | RB | 13 | 8 | 17 | 112 | 6.6 | 0 | 17 | 1.3 | 8.6 | 1 |
| 43 | Billy Miller | 2004 | 27 | HOU | te | 16 | 8 | 17 | 178 | 10.5 | 1 | 27 | 1.1 | 11.1 | 1 |
| 44 | Kevin Walter | 2006 | 25 | HOU | 16 | 2 | 17 | 160 | 9.4 | 0 | 15 | 1.1 | 10.0 | 1 | |
| 45 | Samkon Gado | 2006 | 24 | HOU | 8 | 1 | 16 | 80 | 5.0 | 0 | 19 | 2.0 | 10.0 | 1 | |
| 46 | Jacoby Jones | 2007 | 23 | HOU | RET | 14 | 3 | 15 | 149 | 9.9 | 0 | 26 | 1.1 | 10.6 | 2 |
| 47 | Ron Dayne | 2006 | 28 | HOU | rb | 11 | 6 | 14 | 77 | 5.5 | 0 | 13 | 1.3 | 7.0 | 1 |
| 48 | Ahman Green | 2007 | 30 | HOU | rb | 6 | 5 | 14 | 123 | 8.8 | 0 | 53 | 2.3 | 20.5 | 0 |
| 49 | Andre' Davis | 2008 | 29 | HOU | RET | 12 | 0 | 13 | 213 | 16.4 | 0 | 49 | 1.1 | 17.8 | 0 |
| 50 | Jacoby Jones | 2009 | 25 | HOU | 9 | 13 | 238 | 18.3 | 3 | 45 | 1.4 | 26.4 | 2 | ||
| 51 | Jeb Putzier | 2006 | 27 | HOU | te | 14 | 5 | 13 | 125 | 9.6 | 0 | 26 | 0.9 | 8.9 | 0 |
| 52 | Darius Walker | 2007 | 22 | HOU | 4 | 2 | 13 | 81 | 6.2 | 0 | 9 | 3.3 | 20.3 | 0 | |
| 53 | David Anderson | 2007 | 24 | HOU | 8 | 0 | 12 | 131 | 10.9 | 1 | 24 | 1.5 | 16.4 | 1 | |
| 54 | Vonta Leach | 2009 | 28 | HOU | 7 | 12 | 83 | 6.9 | 0 | 20 | 1.7 | 11.9 | 0 | ||
| 55 | Vonta Leach | 2008 | 27 | HOU | FB | 16 | 12 | 12 | 103 | 8.6 | 0 | 22 | 0.8 | 6.4 | 0 |
| 56 | Joel Dreessen | 2008 | 26 | HOU | 16 | 3 | 11 | 77 | 7.0 | 0 | 13 | 0.7 | 4.8 | 1 | |
| 57 | Ahman Green | 2008 | 31 | HOU | 8 | 1 | 11 | 32 | 2.9 | 0 | 8 | 1.4 | 4.0 | 0 | |
| 58 | Jonathan Wells | 2004 | 25 | HOU | 16 | 1 | 11 | 79 | 7.2 | 2 | 28 | 0.7 | 4.9 | 1 | |
| 59 | Vernand Morency | 2005 | 25 | HOU | 13 | 1 | 10 | 87 | 8.7 | 0 | 16 | 0.8 | 6.7 | 1 | |
| Rk | Year | Age | Tm | Pos | G | GS | Rec | Yds | TD | Lng | Fmb | ||||
| 60 | Derick Armstrong | 2005 | 26 | HOU | 13 | 3 | 9 | 115 | 12.8 | 0 | 28 | 0.7 | 8.8 | 0 | |
| 61 | Mark Bruener | 2006 | 34 | HOU | 15 | 4 | 9 | 62 | 6.9 | 2 | 25 | 0.6 | 4.1 | 0 | |
| 62 | Stacey Mack | 2003 | 28 | HOU | rb | 8 | 5 | 9 | 55 | 6.1 | 0 | 10 | 1.1 | 6.9 | 2 |
| 63 | Jonathan Wells | 2002 | 23 | HOU | RB | 16 | 11 | 9 | 48 | 5.3 | 0 | 9 | 0.6 | 3.0 | 3 |
| 64 | Jameel Cook | 2007 | 28 | HOU | 16 | 0 | 8 | 40 | 5.0 | 0 | 9 | 0.5 | 2.5 | 0 | |
| 65 | Samkon Gado | 2007 | 25 | HOU | 3 | 0 | 8 | 59 | 7.4 | 0 | 20 | 2.7 | 19.7 | 1 | |
| 66 | Jabari Holloway | 2003 | 25 | HOU | TE | 15 | 9 | 8 | 84 | 10.5 | 0 | 33 | 0.5 | 5.6 | 0 |
| 67 | Derick Armstrong | 2003 | 24 | HOU | 8 | 1 | 7 | 75 | 10.7 | 1 | 18 | 0.9 | 9.4 | 0 | |
| 68 | Joel Dreessen | 2009 | 27 | HOU | 6 | 7 | 67 | 9.6 | 0 | 21 | 1.2 | 11.2 | 0 | ||
| 69 | Jabari Holloway | 2002 | 24 | HOU | TE | 11 | 8 | 7 | 73 | 10.4 | 0 | 24 | 0.6 | 6.6 | 0 |
| 70 | Moran Norris | 2003 | 25 | HOU | FB | 16 | 9 | 7 | 40 | 5.7 | 0 | 11 | 0.4 | 2.5 | 0 |
| 71 | Avion Black | 2002 | 25 | HOU | 11 | 0 | 6 | 52 | 8.7 | 0 | 14 | 0.5 | 4.7 | 2 | |
| 72 | Vonta Leach | 2006 | 25 | HOU | 11 | 4 | 6 | 61 | 10.2 | 1 | 19 | 0.5 | 5.5 | 0 | |
| 73 | Jeb Putzier | 2007 | 28 | HOU | 8 | 1 | 6 | 39 | 6.5 | 1 | 11 | 0.8 | 4.9 | 0 | |
| 74 | Jarrod Baxter | 2002 | 23 | HOU | FB | 16 | 10 | 5 | 33 | 6.6 | 1 | 14 | 0.3 | 2.1 | 0 |
| 75 | Chris Brown | 2009 | 28 | HOU | 7 | 5 | 21 | 4.2 | 0 | 9 | 0.7 | 3.0 | 1 | ||
| 76 | Tony Hollings | 2004 | 23 | HOU | 7 | 0 | 5 | 46 | 9.2 | 0 | 27 | 0.7 | 6.6 | 0 | |
| 77 | Jerome Mathis | 2005*+ | 22 | HOU | RET | 12 | 0 | 5 | 65 | 13.0 | 1 | 34 | 0.4 | 5.4 | 3 |
| 78 | Ryan Moats | 2009 | 27 | HOU | 6 | 5 | 40 | 8.0 | 1 | 20 | 0.8 | 6.7 | 1 | ||
| 79 | Mark Bruener | 2004 | 32 | HOU | TE | 16 | 11 | 4 | 52 | 13.0 | 0 | 27 | 0.3 | 3.3 | 0 |
| 80 | Andre' Davis | 2009 | 30 | HOU | 7 | 4 | 28 | 7.0 | 0 | 14 | 0.6 | 4.0 | 0 | ||
| 81 | Joel Dreessen | 2007 | 25 | HOU | 13 | 0 | 4 | 55 | 13.8 | 2 | 28 | 0.3 | 4.2 | 0 | |
| 82 | Donovan Morgan | 2005 | 23 | HOU | 3 | 0 | 4 | 42 | 10.5 | 0 | 14 | 1.3 | 14.0 | 0 | |
| 83 | Moran Norris | 2004 | 26 | HOU | 12 | 4 | 4 | 13 | 3.3 | 0 | 7 | 0.3 | 1.1 | 0 | |
| 84 | Jacoby Jones | 2008 | 24 | HOU | RET | 16 | 0 | 3 | 81 | 27.0 | 0 | 45 | 0.2 | 5.1 | 4 |
| 85 | Ryan Moats | 2008 | 26 | HOU | 9 | 0 | 3 | 14 | 4.7 | 0 | 5 | 0.3 | 1.6 | 0 | |
| 86 | Edell Shepherd | 2006 | 26 | HOU | 7 | 0 | 3 | 22 | 7.3 | 0 | 8 | 0.4 | 3.1 | 2 | |
| 87 | Chris Taylor | 2006 | 23 | HOU | 4 | 0 | 3 | 40 | 13.3 | 0 | 24 | 0.8 | 10.0 | 0 | |
| 88 | Mark Bruener | 2005 | 33 | HOU | TE | 16 | 15 | 2 | 22 | 11.0 | 0 | 19 | 0.1 | 1.4 | 0 |
| 89 | James Casey | 2009 | 25 | HOU | 3 | 2 | 14 | 7.0 | 0 | 7 | 0.7 | 4.7 | 0 | ||
| Rk | Year | Age | Tm | Pos | G | GS | Rec | Yds | TD | Lng | Fmb | ||||
| 90 | Adimchinobe Echemandu | 2007 | 27 | HOU | 7 | 0 | 2 | 11 | 5.5 | 0 | 7 | 0.3 | 1.6 | 1 | |
| 91 | Tony Hollings | 2003 | 22 | HOU | 14 | 1 | 2 | 25 | 12.5 | 0 | 19 | 0.1 | 1.8 | 2 | |
| 92 | Jermaine Lewis | 2002 | 28 | HOU | RET | 12 | 1 | 2 | 41 | 20.5 | 0 | 33 | 0.2 | 3.4 | 3 |
| 93 | Matt Murphy | 2005 | 25 | HOU | 9 | 2 | 2 | 26 | 13.0 | 0 | 14 | 0.2 | 2.9 | 0 | |
| 94 | Jonathan Wells | 2003 | 24 | HOU | 13 | 0 | 2 | 17 | 8.5 | 0 | 12 | 0.2 | 1.3 | 0 | |
| 95 | David Anderson | 2006 | 23 | HOU | 9 | 0 | 1 | 27 | 27.0 | 0 | 27 | 0.1 | 3.0 | 0 | |
| 96 | Jarrod Baxter | 2004 | 25 | HOU | 8 | 1 | 1 | 3 | 3.0 | 0 | 3 | 0.1 | 0.4 | 0 | |
| 97 | Marcus Coleman | 2003 | 29 | HOU | RCB | 15 | 15 | 1 | 6 | 6.0 | 0 | 6 | 0.1 | 0.4 | 0 |
| 98 | Atnaf Harris | 2002 | 23 | HOU | 1 | 1 | 1 | 8 | 8.0 | 0 | 8 | 1.0 | 8.0 | 0 | |
| 99 | Anthony Hill | 2009 | 24 | HOU | 1 | 1 | 9 | 9.0 | 0 | 9 | 1.0 | 9.0 | 0 | ||
| 100 | Derrick Lewis | 2006 | 31 | HOU | 4 | 0 | 1 | 5 | 5.0 | 0 | 5 | 0.3 | 1.3 | 0 | |
| 101 | Jerome Mathis | 2007 | 24 | HOU | 3 | 0 | 1 | 15 | 15.0 | 0 | 15 | 0.3 | 5.0 | 0 | |
| 102 | Vernand Morency | 2006 | 26 | HOU | 1 | 0 | 1 | 6 | 6.0 | 0 | 6 | 1.0 | 6.0 | 0 | |
| 103 | Moran Norris | 2005 | 27 | HOU | FB | 16 | 5 | 1 | 4 | 4.0 | 1 | 4 | 0.1 | 0.3 | 0 |
| 104 | Dave Ragone | 2003 | 24 | HOU | 2 | 2 | 1 | -5 | -5.0 | 0 | -5 | 0.5 | -2.5 | 4 |