| Single-season | Passing | Rushing | Receiving | Returns | Kicking | Scoring | |
| Career | Passing | Rushing | Receiving | Returns | Kicking | Scoring | Defense |
| Rushing | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rk | Year | Age | Tm | Pos | G | GS | Att | Yds | TD | Lng | Fmb | |||
| 1 | Domanick Williams | 2004 | 24 | HOU | RB | 15 | 15 | 302 | 1188 | 13 | 44 | 3.9 | 79.2 | 4 |
| 2 | Steve Slaton | 2008 | 22 | HOU | RB | 16 | 15 | 268 | 1282 | 9 | 71 | 4.8 | 80.1 | 3 |
| 3 | Domanick Williams | 2003 | 23 | HOU | RB | 14 | 10 | 238 | 1031 | 8 | 51 | 4.3 | 73.6 | 4 |
| 4 | Domanick Williams | 2005 | 25 | HOU | RB | 11 | 11 | 230 | 976 | 2 | 44 | 4.2 | 88.7 | 2 |
| 5 | Jonathan Wells | 2002 | 23 | HOU | RB | 16 | 11 | 197 | 529 | 3 | 37 | 2.7 | 33.1 | 3 |
| 6 | Ron Dayne | 2007 | 29 | HOU | RB | 13 | 8 | 194 | 773 | 6 | 39 | 4.0 | 59.5 | 1 |
| 7 | James Allen | 2002 | 27 | HOU | rb | 16 | 5 | 155 | 519 | 0 | 32 | 3.3 | 32.4 | 1 |
| 8 | Ron Dayne | 2006 | 28 | HOU | rb | 11 | 6 | 151 | 612 | 5 | 19 | 4.1 | 55.6 | 1 |
| 9 | Wali Lundy | 2006 | 23 | HOU | RB | 14 | 8 | 124 | 476 | 4 | 35 | 3.8 | 34.0 | 1 |
| 10 | Steve Slaton | 2009 | 23 | HOU | 9 | 116 | 359 | 3 | 32 | 3.1 | 39.9 | 7 | ||
| 11 | Stacey Mack | 2003 | 28 | HOU | rb | 8 | 5 | 93 | 253 | 4 | 13 | 2.7 | 31.6 | 2 |
| 12 | Jonathan Wells | 2005 | 26 | HOU | rb | 15 | 6 | 90 | 325 | 4 | 14 | 3.6 | 21.7 | 1 |
| 13 | Jonathan Wells | 2004 | 25 | HOU | 16 | 1 | 82 | 299 | 3 | 14 | 3.6 | 18.7 | 1 | |
| 14 | Ahman Green | 2008 | 31 | HOU | 8 | 1 | 74 | 294 | 3 | 14 | 4.0 | 36.8 | 0 | |
| 15 | David Carr | 2004 | 25 | HOU | QB | 16 | 16 | 73 | 299 | 0 | 24 | 4.1 | 18.7 | 10 |
| 16 | Ahman Green | 2007 | 30 | HOU | rb | 6 | 5 | 70 | 260 | 2 | 18 | 3.7 | 43.3 | 0 |
| 17 | David Carr | 2002 | 23 | HOU | QB | 16 | 16 | 59 | 282 | 3 | 20 | 4.8 | 17.6 | 21 |
| 18 | Darius Walker | 2007 | 22 | HOU | 4 | 2 | 58 | 264 | 1 | 41 | 4.6 | 66.0 | 0 | |
| 19 | David Carr | 2005 | 26 | HOU | QB | 16 | 16 | 56 | 308 | 1 | 20 | 5.5 | 19.3 | 17 |
| 20 | Samkon Gado | 2006 | 24 | HOU | 8 | 1 | 54 | 217 | 1 | 34 | 4.0 | 27.1 | 1 | |
| 21 | Ryan Moats | 2009 | 27 | HOU | 6 | 54 | 220 | 3 | 17 | 4.1 | 36.7 | 1 | ||
| 22 | David Carr | 2006 | 27 | HOU | QB | 16 | 16 | 53 | 195 | 2 | 16 | 3.7 | 12.2 | 16 |
| 23 | Vernand Morency | 2005 | 25 | HOU | 13 | 1 | 46 | 184 | 2 | 25 | 4.0 | 14.2 | 1 | |
| 24 | Chris Brown | 2009 | 28 | HOU | 7 | 43 | 142 | 1 | 13 | 3.3 | 20.3 | 1 | ||
| 25 | Tony Hollings | 2003 | 22 | HOU | 14 | 1 | 38 | 102 | 0 | 17 | 2.7 | 7.3 | 2 | |
| 26 | Matt Schaub | 2009 | 28 | HOU | 9 | 33 | 51 | 0 | 19 | 1.5 | 5.7 | 1 | ||
| 27 | Matt Schaub | 2008 | 27 | HOU | QB | 11 | 11 | 31 | 68 | 2 | 10 | 2.2 | 6.2 | 10 |
| 28 | Chris Taylor | 2006 | 23 | HOU | 4 | 0 | 28 | 123 | 1 | 17 | 4.4 | 30.8 | 0 | |
| 29 | David Carr | 2003 | 24 | HOU | QB | 12 | 11 | 27 | 151 | 2 | 36 | 5.6 | 12.6 | 4 |
| Rushing | ||||||||||||||
| Rk | Year | Age | Tm | Pos | G | GS | Att | Yds | TD | Lng | Fmb | |||
| 30 | Ryan Moats | 2008 | 26 | HOU | 9 | 0 | 26 | 94 | 1 | 12 | 3.6 | 10.4 | 0 | |
| 31 | Sage Rosenfels | 2007 | 29 | HOU | qb | 9 | 5 | 21 | 51 | 1 | 19 | 2.4 | 5.7 | 4 |
| 32 | Adimchinobe Echemandu | 2007 | 27 | HOU | 7 | 0 | 20 | 85 | 0 | 20 | 4.3 | 12.1 | 1 | |
| 33 | Samkon Gado | 2007 | 25 | HOU | 3 | 0 | 18 | 46 | 1 | 7 | 2.6 | 15.3 | 1 | |
| 34 | Matt Schaub | 2007 | 26 | HOU | QB | 11 | 11 | 17 | 52 | 0 | 12 | 3.1 | 4.7 | 7 |
| 35 | Chris Taylor | 2008 | 25 | HOU | 3 | 0 | 14 | 37 | 0 | 17 | 2.6 | 12.3 | 1 | |
| 36 | Tony Hollings | 2004 | 23 | HOU | 7 | 0 | 11 | 47 | 0 | 13 | 4.3 | 6.7 | 0 | |
| 37 | Sage Rosenfels | 2008 | 30 | HOU | qb | 6 | 5 | 11 | 37 | 0 | 15 | 3.4 | 6.2 | 4 |
| 38 | Jameel Cook | 2007 | 28 | HOU | 16 | 0 | 8 | 24 | 0 | 9 | 3.0 | 1.5 | 0 | |
| 39 | Jarrod Baxter | 2002 | 23 | HOU | FB | 16 | 10 | 7 | 14 | 0 | 6 | 2.0 | 0.9 | 0 |
| 40 | Tony Banks | 2003 | 30 | HOU | 7 | 3 | 6 | 27 | 0 | 13 | 4.5 | 3.9 | 1 | |
| 41 | Andre Johnson | 2005 | 24 | HOU | WR | 13 | 13 | 6 | 10 | 0 | 5 | 1.7 | 0.8 | 1 |
| 42 | Dave Ragone | 2003 | 24 | HOU | 2 | 2 | 6 | 51 | 0 | 14 | 8.5 | 25.5 | 4 | |
| 43 | Andre Johnson | 2003 | 22 | HOU | WR | 16 | 16 | 5 | -10 | 0 | 11 | -2.0 | -0.6 | 0 |
| 44 | Vernand Morency | 2006 | 26 | HOU | 1 | 0 | 5 | 13 | 0 | 12 | 2.6 | 13.0 | 0 | |
| 45 | Kevin Walter | 2007 | 26 | HOU | WR | 16 | 15 | 5 | 30 | 0 | 13 | 6.0 | 1.9 | 0 |
| 46 | Jonathan Wells | 2003 | 24 | HOU | 13 | 0 | 5 | 14 | 0 | 10 | 2.8 | 1.1 | 0 | |
| 47 | Jabar Gaffney | 2005 | 25 | HOU | WR | 16 | 13 | 4 | 13 | 0 | 10 | 3.3 | 0.8 | 0 |
| 48 | Jabar Gaffney | 2004 | 24 | HOU | WR | 16 | 12 | 4 | 30 | 0 | 10 | 7.5 | 1.9 | 1 |
| 49 | Andre Johnson | 2004* | 23 | HOU | WR | 16 | 16 | 4 | 12 | 0 | 14 | 3.0 | 0.8 | 1 |
| 50 | Sage Rosenfels | 2006 | 28 | HOU | 4 | 0 | 4 | 5 | 0 | 7 | 1.3 | 1.3 | 0 | |
| 51 | Jameel Cook | 2006 | 27 | HOU | FB | 11 | 6 | 3 | 18 | 0 | 14 | 6.0 | 1.6 | 2 |
| 52 | Andre Johnson | 2006* | 25 | HOU | WR | 16 | 16 | 3 | 14 | 0 | 18 | 4.7 | 0.9 | 1 |
| 53 | Jacoby Jones | 2007 | 23 | HOU | RET | 14 | 3 | 3 | -1 | 0 | 4 | -0.3 | -0.1 | 2 |
| 54 | Jermaine Lewis | 2002 | 28 | HOU | RET | 12 | 1 | 3 | 8 | 0 | 5 | 2.7 | 0.7 | 3 |
| 55 | Kevin Walter | 2008 | 27 | HOU | WR | 16 | 16 | 3 | 23 | 0 | 13 | 7.7 | 1.4 | 0 |
| 56 | Kevin Walter | 2009 | 28 | HOU | 7 | 3 | 23 | 0 | 13 | 7.7 | 3.3 | 0 | ||
| 57 | Tony Banks | 2005 | 32 | HOU | 3 | 0 | 2 | -2 | 0 | -1 | -1.0 | -0.7 | 0 | |
| 58 | Jarrod Baxter | 2004 | 25 | HOU | 8 | 1 | 2 | 1 | 0 | 1 | 0.5 | 0.1 | 0 | |
| 59 | Corey Bradford | 2002 | 27 | HOU | WR | 16 | 16 | 2 | -11 | 0 | 0 | -5.5 | -0.7 | 0 |
| Rushing | ||||||||||||||
| Rk | Year | Age | Tm | Pos | G | GS | Att | Yds | TD | Lng | Fmb | |||
| 60 | Jacoby Jones | 2009 | 25 | HOU | 9 | 2 | 22 | 0 | 17 | 11.0 | 2.4 | 2 | ||
| 61 | Vonta Leach | 2007 | 26 | HOU | FB | 16 | 12 | 2 | 2 | 1 | 1 | 1.0 | 0.1 | 2 |
| 62 | Cecil Sapp | 2008 | 30 | HOU | 12 | 0 | 2 | -3 | 0 | 0 | -1.5 | -0.3 | 0 | |
| 63 | Edell Shepherd | 2006 | 26 | HOU | 7 | 0 | 2 | 5 | 0 | 6 | 2.5 | 0.7 | 2 | |
| 64 | Corey Bradford | 2005 | 30 | HOU | wr | 16 | 6 | 1 | -2 | 0 | -2 | -2.0 | -0.1 | 0 |
| 65 | Kris Brown | 2005 | 29 | HOU | K | 16 | 0 | 1 | 4 | 0 | 4 | 4.0 | 0.3 | 0 |
| 66 | Jabar Gaffney | 2003 | 23 | HOU | WR | 16 | 11 | 1 | 13 | 0 | 13 | 13.0 | 0.8 | 0 |
| 67 | Jacoby Jones | 2008 | 24 | HOU | RET | 16 | 0 | 1 | -5 | 0 | -5 | -5.0 | -0.3 | 4 |
| 68 | Vonta Leach | 2008 | 27 | HOU | FB | 16 | 12 | 1 | 1 | 1 | 1 | 1.0 | 0.1 | 0 |
| 69 | Eric Moulds | 2006 | 33 | HOU | WR | 16 | 16 | 1 | 6 | 0 | 6 | 6.0 | 0.4 | 1 |
| 70 | Moran Norris | 2004 | 26 | HOU | 12 | 4 | 1 | 0 | 0 | 0 | 0.0 | 0.0 | 0 | |
| 71 | Jason Simmons | 2006 | 30 | HOU | 16 | 2 | 1 | 0 | 0 | 0 | 0.0 | 0.0 | 0 | |
| 72 | Jason Simmons | 2003 | 27 | HOU | 16 | 2 | 1 | 7 | 0 | 7 | 7.0 | 0.4 | 0 | |
| 73 | Jason Simmons | 2004 | 28 | HOU | fs | 10 | 6 | 1 | 1 | 0 | 1 | 1.0 | 0.1 | 0 |
| 74 | Chad Stanley | 2006 | 30 | HOU | P | 16 | 0 | 1 | 0 | 0 | 0 | 0.0 | 0.0 | 1 |
| 75 | Chad Stanley | 2004 | 28 | HOU | P | 16 | 0 | 1 | 5 | 0 | 5 | 5.0 | 0.3 | 0 |
| 76 | Chad Stanley | 2002 | 26 | HOU | P | 16 | 0 | 1 | 6 | 0 | 6 | 6.0 | 0.4 | 0 |
| 77 | Chad Stanley | 2005 | 29 | HOU | P | 16 | 0 | 1 | 0 | 0 | 0 | 0.0 | 0.0 | 1 |
| 78 | Chad Stanley | 2003 | 27 | HOU | P | 16 | 0 | 1 | 12 | 0 | 12 | 12.0 | 0.8 | 0 |
| 79 | Matt Turk | 2007 | 39 | HOU | P | 16 | 0 | 1 | 0 | 0 | 0 | 0.0 | 0.0 | 0 |
| 80 | Matt Turk | 2008 | 40 | HOU | P | 16 | 0 | 1 | 18 | 0 | 18 | 18.0 | 1.1 | 1 |
| 81 | Kevin Walter | 2006 | 25 | HOU | 16 | 2 | 1 | 3 | 0 | 3 | 3.0 | 0.2 | 1 | |