| Single-season | Passing | Rushing | Receiving | Returns | Kicking | Scoring | |
| Career | Passing | Rushing | Receiving | Returns | Kicking | Scoring | Defense |
| Rushing | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rk | Year | Age | Tm | Pos | G | GS | Att | Yds | TD | Lng | Fmb | |||
| 1 | Frank Gore | 2006* | 23 | SFO | RB | 16 | 16 | 312 | 1695 | 8 | 72 | 5.4 | 105.9 | 6 |
| 2 | Roger Craig | 1988*+ | 28 | SFO | RB | 16 | 15 | 310 | 1502 | 9 | 46 | 4.8 | 93.9 | 8 |
| 3 | Garrison Hearst | 1998* | 27 | SFO | RB | 16 | 16 | 310 | 1570 | 7 | 96 | 5.1 | 98.1 | 4 |
| 4 | Roger Craig | 1989* | 29 | SFO | RB | 16 | 16 | 271 | 1054 | 6 | 27 | 3.9 | 65.9 | 4 |
| 5 | Delvin Williams | 1977 | 26 | SFO | RB | 14 | 14 | 268 | 931 | 7 | 40 | 3.5 | 66.5 | 3 |
| 6 | Frank Gore | 2007 | 24 | SFO | RB | 15 | 15 | 260 | 1102 | 5 | 43 | 4.2 | 73.5 | 4 |
| 7 | Charlie Garner | 2000* | 28 | SFO | RB | 16 | 15 | 258 | 1142 | 7 | 42 | 4.4 | 71.4 | 4 |
| 8 | J.D. Smith | 1962* | 30 | SFO | FB | 14 | 14 | 258 | 907 | 6 | 28 | 3.5 | 64.8 | 1 |
| 9 | Garrison Hearst | 2001* | 30 | SFO | RB | 16 | 16 | 252 | 1206 | 4 | 43 | 4.8 | 75.4 | 1 |
| 10 | Delvin Williams | 1976* | 25 | SFO | RB | 13 | 13 | 248 | 1203 | 7 | 80 | 4.9 | 92.5 | 6 |
| 11 | Wendell Tyler | 1984* | 29 | SFO | RB | 16 | 15 | 246 | 1262 | 7 | 40 | 5.1 | 78.9 | 13 |
| 12 | Kevan Barlow | 2004 | 25 | SFO | RB | 15 | 14 | 244 | 822 | 7 | 60 | 3.4 | 54.8 | 2 |
| 13 | Charlie Garner | 1999 | 27 | SFO | RB | 16 | 15 | 241 | 1229 | 4 | 53 | 5.1 | 76.8 | 4 |
| 14 | Ricky Watters | 1994* | 25 | SFO | RB | 16 | 16 | 239 | 877 | 6 | 23 | 3.7 | 54.8 | 8 |
| 15 | Ken Willard | 1970 | 27 | SFO | FB | 14 | 14 | 236 | 789 | 7 | 20 | 3.3 | 56.4 | 3 |
| 16 | Garrison Hearst | 1997 | 26 | SFO | RB | 13 | 13 | 234 | 1019 | 4 | 51 | 4.4 | 78.4 | 2 |
| 17 | Ken Willard | 1968* | 25 | SFO | FB | 14 | 14 | 227 | 967 | 7 | 69 | 4.3 | 69.1 | 4 |
| 18 | Derek Loville | 1995 | 27 | SFO | RB | 16 | 16 | 218 | 723 | 10 | 27 | 3.3 | 45.2 | 1 |
| 19 | Ken Willard | 1971 | 28 | SFO | FB | 14 | 14 | 216 | 855 | 4 | 49 | 4.0 | 61.1 | 8 |
| 20 | Roger Craig | 1987* | 27 | SFO | RB/fb | 14 | 14 | 215 | 815 | 3 | 25 | 3.8 | 58.2 | 5 |
| 21 | Garrison Hearst | 2002 | 31 | SFO | RB | 16 | 16 | 215 | 972 | 8 | 40 | 4.5 | 60.8 | 4 |
| 22 | Roger Craig | 1985* | 25 | SFO | FB | 16 | 16 | 214 | 1050 | 9 | 62 | 4.9 | 65.6 | 5 |
| 23 | Ricky Watters | 1993* | 24 | SFO | RB | 13 | 13 | 208 | 950 | 10 | 39 | 4.6 | 73.1 | 5 |
| 24 | J.D. Smith | 1959* | 27 | SFO | LH | 12 | 0 | 207 | 1036 | 10 | 73 | 5.0 | 86.3 | 3 |
| 25 | Ricky Watters | 1992* | 23 | SFO | RB | 14 | 13 | 206 | 1013 | 9 | 43 | 4.9 | 72.4 | 2 |
| 26 | Roger Craig | 1986 | 26 | SFO | FB | 16 | 15 | 204 | 830 | 7 | 25 | 4.1 | 51.9 | 4 |
| 27 | Kevan Barlow | 2003 | 24 | SFO | rb | 16 | 4 | 201 | 1024 | 6 | 78 | 5.1 | 64.0 | 5 |
| 28 | Wilbur Jackson | 1976 | 25 | SFO | FB | 14 | 14 | 200 | 792 | 1 | 24 | 4.0 | 56.6 | 3 |
| 29 | Joe Perry | 1953*+ | 26 | SFO | FB | 12 | 0 | 192 | 1018 | 10 | 51 | 5.3 | 84.8 | 8 |
| Rushing | ||||||||||||||
| Rk | Year | Age | Tm | Pos | G | GS | Att | Yds | TD | Lng | Fmb | |||
| 30 | Vic Washington | 1971* | 25 | SFO | RB | 14 | 0 | 191 | 811 | 3 | 42 | 4.2 | 57.9 | 10 |
| 31 | Ken Willard | 1966* | 23 | SFO | FB | 14 | 14 | 191 | 763 | 5 | 49 | 4.0 | 54.5 | 7 |
| 32 | Ken Willard | 1965* | 22 | SFO | FB | 14 | 14 | 189 | 778 | 5 | 32 | 4.1 | 55.6 | 7 |
| 33 | Hugh McElhenny | 1956* | 28 | SFO | LH | 12 | 0 | 185 | 916 | 8 | 86 | 5.0 | 76.3 | 4 |
| 34 | Wilbur Jackson | 1977 | 26 | SFO | FB | 14 | 14 | 179 | 780 | 7 | 80 | 4.4 | 55.7 | 3 |
| 35 | Garrison Hearst | 2003 | 32 | SFO | RB | 12 | 12 | 178 | 768 | 3 | 36 | 4.3 | 64.0 | 2 |
| 36 | Kevan Barlow | 2005 | 26 | SFO | RB | 12 | 12 | 176 | 581 | 3 | 29 | 3.3 | 48.4 | 2 |
| 37 | Roger Craig | 1983 | 23 | SFO | FB | 16 | 13 | 176 | 725 | 8 | 71 | 4.1 | 45.3 | 6 |
| 38 | Wendell Tyler | 1983 | 28 | SFO | RB | 14 | 14 | 176 | 856 | 4 | 39 | 4.9 | 61.1 | 7 |
| 39 | Wilbur Jackson | 1974 | 23 | SFO | RB | 14 | 13 | 174 | 705 | 0 | 64 | 4.1 | 50.4 | 4 |
| 40 | Larry Schreiber | 1974 | 27 | SFO | FB | 14 | 14 | 174 | 634 | 3 | 21 | 3.6 | 45.3 | 2 |
| 41 | J.D. Smith | 1960 | 28 | SFO | FB/lh | 12 | 12 | 174 | 780 | 5 | 41 | 4.5 | 65.0 | 1 |
| 42 | Joe Perry | 1954*+ | 27 | SFO | FB | 12 | 0 | 173 | 1049 | 8 | 58 | 6.1 | 87.4 | 6 |
| 43 | Earl Cooper | 1980 | 23 | SFO | FB | 16 | 16 | 171 | 720 | 5 | 47 | 4.2 | 45.0 | 8 |
| 44 | Wendell Tyler | 1985 | 30 | SFO | RB | 13 | 12 | 171 | 867 | 6 | 30 | 5.1 | 66.7 | 6 |
| 45 | Ken Willard | 1969* | 26 | SFO | FB | 14 | 14 | 171 | 557 | 7 | 18 | 3.3 | 39.8 | 6 |
| 46 | Ken Willard | 1967 | 24 | SFO | FB | 13 | 13 | 169 | 510 | 5 | 20 | 3.0 | 39.2 | 1 |
| 47 | J.D. Smith | 1961 | 29 | SFO | LH | 14 | 12 | 167 | 823 | 8 | 33 | 4.9 | 58.8 | 3 |
| 48 | J.D. Smith | 1963 | 31 | SFO | FB | 14 | 13 | 162 | 560 | 5 | 52 | 3.5 | 40.0 | 4 |
| 49 | O.J. Simpson | 1978 | 31 | SFO | RB | 10 | 10 | 161 | 593 | 1 | 34 | 3.7 | 59.3 | 5 |
| 50 | Joe Perry | 1952* | 25 | SFO | FB | 12 | 0 | 158 | 725 | 8 | 78 | 4.6 | 60.4 | 6 |
| 51 | Joe Perry | 1955 | 28 | SFO | FB | 11 | 0 | 156 | 701 | 2 | 42 | 4.5 | 63.7 | 6 |
| 52 | Roger Craig | 1984 | 24 | SFO | FB | 16 | 16 | 155 | 649 | 7 | 28 | 4.2 | 40.6 | 3 |
| 53 | Joe Cribbs | 1986 | 28 | SFO | RB | 14 | 10 | 152 | 590 | 5 | 19 | 3.9 | 42.1 | 5 |
| 54 | Ricky Patton | 1981 | 27 | SFO | RB | 16 | 15 | 152 | 543 | 4 | 28 | 3.6 | 33.9 | 3 |
| 55 | Vic Washington | 1973 | 27 | SFO | RB | 13 | 13 | 151 | 534 | 8 | 25 | 3.5 | 41.1 | 9 |
| 56 | Doug Cunningham | 1969 | 24 | SFO | HB | 14 | 13 | 147 | 541 | 3 | 33 | 3.7 | 38.6 | 5 |
| 57 | Kevan Barlow | 2002 | 23 | SFO | 14 | 0 | 145 | 675 | 4 | 35 | 4.7 | 48.2 | 2 | |
| 58 | Norm Standlee | 1947 | 28 | SFO | FB | 14 | 12 | 145 | 585 | 8 | 0 | 4.0 | 41.8 | 0 |
| 59 | Johnny Strzykalski | 1947 | 26 | SFO | RH | 14 | 13 | 143 | 906 | 5 | 50 | 6.3 | 64.7 | 0 |
| Rushing | ||||||||||||||
| Rk | Year | Age | Tm | Pos | G | GS | Att | Yds | TD | Lng | Fmb | |||
| 60 | Roger Craig | 1990 | 30 | SFO | RB | 11 | 11 | 141 | 439 | 1 | 26 | 3.1 | 39.9 | 2 |
| 61 | Gary Lewis | 1968 | 26 | SFO | HB | 14 | 14 | 141 | 573 | 1 | 22 | 4.1 | 40.9 | 3 |
| 62 | Johnny Strzykalski | 1948 | 27 | SFO | RH | 14 | 13 | 141 | 915 | 4 | 48 | 6.5 | 65.4 | 0 |
| 63 | Vic Washington | 1972 | 26 | SFO | RB | 13 | 13 | 141 | 468 | 3 | 33 | 3.3 | 36.0 | 7 |
| 64 | Joe Perry | 1959 | 32 | SFO | FB | 11 | 0 | 139 | 602 | 3 | 40 | 4.3 | 54.7 | 6 |
| 65 | Keith Henderson | 1991 | 25 | SFO | 14 | 1 | 137 | 561 | 2 | 25 | 4.1 | 40.1 | 4 | |
| 66 | Joe Perry | 1951 | 24 | SFO | FB | 11 | 0 | 136 | 677 | 3 | 58 | 5.0 | 61.5 | 5 |
| 67 | Johnny Strzykalski | 1950* | 29 | SFO | RH | 12 | 0 | 136 | 612 | 2 | 38 | 4.5 | 51.0 | 2 |
| 68 | Terry Kirby | 1996 | 26 | SFO | RB | 14 | 10 | 134 | 559 | 3 | 31 | 4.2 | 39.9 | 1 |
| 69 | Larry Schreiber | 1975 | 28 | SFO | FB | 14 | 14 | 134 | 337 | 5 | 15 | 2.5 | 24.1 | 6 |
| 70 | Norm Standlee | 1946 | 27 | SFO | FB | 13 | 10 | 134 | 651 | 2 | 0 | 4.9 | 50.1 | 0 |
| 71 | John David Crow | 1965* | 30 | SFO | LH | 14 | 13 | 132 | 514 | 2 | 30 | 3.9 | 36.7 | 5 |
| 72 | John Henry Johnson | 1954* | 25 | SFO | LH | 12 | 0 | 129 | 681 | 9 | 38 | 5.3 | 56.8 | 5 |
| 73 | Doug Cunningham | 1970 | 25 | SFO | RB | 12 | 0 | 128 | 443 | 3 | 25 | 3.5 | 36.9 | 4 |
| 74 | Frank Gore | 2005 | 22 | SFO | 14 | 1 | 127 | 608 | 3 | 72 | 4.8 | 43.4 | 2 | |
| 75 | Kevan Barlow | 2001 | 22 | SFO | 15 | 0 | 125 | 512 | 4 | 25 | 4.1 | 34.1 | 1 | |
| 76 | Bob Ferrell | 1978 | 26 | SFO | fb | 16 | 8 | 125 | 471 | 1 | 20 | 3.8 | 29.4 | 5 |
| 77 | Terry Kirby | 1997 | 27 | SFO | 16 | 3 | 125 | 418 | 6 | 38 | 3.3 | 26.1 | 3 | |
| 78 | Joe Perry | 1958 | 31 | SFO | FB | 12 | 0 | 125 | 758 | 4 | 73 | 6.1 | 63.2 | 3 |
| 79 | Joe Perry | 1950 | 23 | SFO | FB | 12 | 0 | 124 | 647 | 5 | 78 | 5.2 | 53.9 | 11 |
| 80 | Paul Hofer | 1979 | 27 | SFO | rb | 15 | 7 | 123 | 615 | 7 | 47 | 5.0 | 41.0 | 3 |
| 81 | John David Crow | 1966 | 31 | SFO | HB | 14 | 14 | 121 | 477 | 1 | 31 | 3.9 | 34.1 | 1 |
| 82 | Paul Hofer | 1978 | 26 | SFO | rb | 16 | 6 | 121 | 465 | 7 | 40 | 3.8 | 29.1 | 4 |
| 83 | O.J. Simpson | 1979 | 32 | SFO | RB | 13 | 8 | 120 | 460 | 3 | 22 | 3.8 | 35.4 | 3 |
| 84 | Larry Schreiber | 1972 | 25 | SFO | 14 | 0 | 118 | 420 | 2 | 20 | 3.6 | 30.0 | 4 | |
| 85 | Delvin Williams | 1975 | 24 | SFO | RB | 14 | 10 | 117 | 631 | 3 | 52 | 5.4 | 45.1 | 1 |
| 86 | Joe Perry | 1956 | 29 | SFO | FB | 11 | 0 | 115 | 520 | 3 | 39 | 4.5 | 47.3 | 3 |
| 87 | Joe Perry | 1949 | 22 | SFO | fb | 11 | 5 | 115 | 783 | 8 | 59 | 6.8 | 71.2 | 0 |
| 88 | Dexter Carter | 1990 | 23 | SFO | rb | 16 | 5 | 114 | 460 | 1 | 74 | 4.0 | 28.8 | 8 |
| 89 | Wilbur Jackson | 1979 | 28 | SFO | FB | 16 | 14 | 114 | 375 | 2 | 16 | 3.3 | 23.4 | 6 |
| Rushing | ||||||||||||||
| Rk | Year | Age | Tm | Pos | G | GS | Att | Yds | TD | Lng | Fmb | |||
| 90 | John David Crow | 1967 | 32 | SFO | HB | 14 | 14 | 113 | 479 | 2 | 39 | 4.2 | 34.2 | 1 |
| 91 | Hugh McElhenny | 1958* | 30 | SFO | LH | 12 | 0 | 113 | 451 | 6 | 34 | 4.0 | 37.6 | 10 |
| 92 | Hugh McElhenny | 1953*+ | 25 | SFO | RH | 12 | 0 | 112 | 503 | 3 | 33 | 4.5 | 41.9 | 6 |
| 93 | Don Lisbon | 1963 | 22 | SFO | LH | 14 | 8 | 109 | 399 | 0 | 25 | 3.7 | 28.5 | 4 |
| 94 | Gene Babb | 1957 | 23 | SFO | FB | 12 | 0 | 102 | 330 | 3 | 19 | 3.2 | 27.5 | 4 |
| 95 | Greg Boykin | 1978 | 25 | SFO | FB | 16 | 8 | 102 | 361 | 2 | 23 | 3.5 | 22.6 | 3 |
| 96 | Hugh McElhenny | 1957* | 29 | SFO | LH | 12 | 0 | 102 | 478 | 1 | 61 | 4.7 | 39.8 | 8 |
| 97 | Tom Rathman | 1988 | 26 | SFO | FB | 16 | 16 | 102 | 427 | 2 | 26 | 4.2 | 26.7 | 0 |
| 98 | Tom Rathman | 1990 | 28 | SFO | FB | 16 | 16 | 101 | 318 | 7 | 22 | 3.1 | 19.9 | 2 |
| 99 | Mike Lind | 1964 | 24 | SFO | FB | 13 | 9 | 100 | 256 | 7 | 21 | 2.6 | 19.7 | 3 |
| 100 | Ken Willard | 1972 | 29 | SFO | FB | 14 | 11 | 100 | 345 | 4 | 23 | 3.5 | 24.6 | 3 |
| 101 | Earl Cooper | 1981 | 24 | SFO | FB | 16 | 11 | 98 | 330 | 1 | 23 | 3.4 | 20.6 | 3 |
| 102 | Hugh McElhenny | 1952*+ | 24 | SFO | RH | 12 | 0 | 98 | 684 | 6 | 89 | 7.0 | 57.0 | 5 |
| 103 | Joe Perry | 1957 | 30 | SFO | 8 | 0 | 97 | 454 | 3 | 34 | 4.7 | 56.8 | 3 | |
| 104 | Maurice Hicks | 2004 | 26 | SFO | RET | 9 | 2 | 96 | 362 | 2 | 35 | 3.8 | 40.2 | 3 |
| 105 | Billy Kilmer | 1961 | 22 | SFO | 11 | 0 | 96 | 509 | 10 | 31 | 5.3 | 46.3 | 8 | |
| 106 | Hugh McElhenny | 1960 | 32 | SFO | LH | 9 | 7 | 95 | 347 | 0 | 38 | 3.7 | 38.6 | 2 |
| 107 | Johnny Davis | 1981 | 25 | SFO | rb | 16 | 5 | 94 | 297 | 7 | 14 | 3.2 | 18.6 | 1 |
| 108 | Billy Kilmer | 1962 | 23 | SFO | LH | 12 | 10 | 93 | 478 | 5 | 35 | 5.1 | 39.8 | 5 |
| 109 | Amp Lee | 1992 | 21 | SFO | 16 | 3 | 91 | 362 | 2 | 43 | 4.0 | 22.6 | 1 | |
| 110 | Hugh McElhenny | 1955 | 27 | SFO | RH | 12 | 0 | 90 | 327 | 4 | 44 | 3.6 | 27.3 | 3 |
| 111 | William Floyd | 1994 | 22 | SFO | FB | 16 | 11 | 87 | 305 | 6 | 26 | 3.5 | 19.1 | 0 |
| 112 | Dexter Carter | 1991 | 24 | SFO | RB | 16 | 14 | 85 | 379 | 2 | 53 | 4.5 | 23.7 | 5 |
| 113 | Jeff Moore | 1982 | 26 | SFO | RB | 9 | 4 | 85 | 281 | 4 | 19 | 3.3 | 31.2 | 4 |
| 114 | Len Eshmont | 1947 | 30 | SFO | LH | 13 | 13 | 84 | 381 | 0 | 0 | 4.5 | 29.3 | 0 |
| 115 | Ken Willard | 1973 | 30 | SFO | FB | 14 | 10 | 83 | 366 | 1 | 33 | 4.4 | 26.1 | 2 |
| 116 | Johnny Strzykalski | 1951 | 30 | SFO | RH | 11 | 0 | 81 | 296 | 3 | 13 | 3.7 | 26.9 | 0 |
| 117 | John Henry Johnson | 1956 | 27 | SFO | fb | 12 | 0 | 80 | 301 | 2 | 54 | 3.8 | 25.1 | 1 |
| 118 | Tom Rathman | 1989 | 27 | SFO | FB | 16 | 16 | 79 | 305 | 1 | 13 | 3.9 | 19.1 | 1 |
| 119 | Johnny Strzykalski | 1946 | 25 | SFO | RH | 13 | 11 | 79 | 346 | 2 | 50 | 4.4 | 26.6 | 0 |
| Rushing | ||||||||||||||
| Rk | Year | Age | Tm | Pos | G | GS | Att | Yds | TD | Lng | Fmb | |||
| 120 | William Floyd | 1997 | 25 | SFO | FB | 15 | 15 | 78 | 231 | 3 | 22 | 3.0 | 15.4 | 2 |
| 121 | Wilbur Jackson | 1975 | 24 | SFO | 14 | 4 | 78 | 303 | 0 | 44 | 3.9 | 21.6 | 8 | |
| 122 | Joe Perry | 1948 | 21 | SFO | 14 | 0 | 77 | 562 | 10 | 57 | 7.3 | 40.1 | 0 | |
| 123 | Walt Easley | 1981 | 24 | SFO | 12 | 1 | 76 | 224 | 1 | 9 | 2.9 | 18.7 | 2 | |
| 124 | Lenvil Elliott | 1980 | 29 | SFO | 15 | 3 | 76 | 341 | 2 | 20 | 4.5 | 22.7 | 5 | |
| 125 | Pete Schabarum | 1951 | 22 | SFO | rh | 12 | 0 | 76 | 311 | 2 | 67 | 4.1 | 25.9 | 4 |
| 126 | Steve Young | 1992*+ | 31 | SFO | QB | 16 | 16 | 76 | 537 | 4 | 39 | 7.1 | 33.6 | 9 |
| 127 | Dave Kopay | 1964 | 22 | SFO | rh | 14 | 5 | 75 | 271 | 0 | 18 | 3.6 | 19.4 | 3 |
| 128 | Earle Parsons | 1946 | 76 | SFO | 10 | 2 | 74 | 362 | 2 | 0 | 4.9 | 36.2 | 0 | |
| 129 | Len Eshmont | 1946 | 29 | SFO | LH | 10 | 9 | 73 | 340 | 6 | 0 | 4.7 | 34.0 | 0 |
| 130 | Jeff Garcia | 2002* | 32 | SFO | QB | 16 | 16 | 73 | 353 | 3 | 21 | 4.8 | 22.1 | 2 |
| 131 | C.R. Roberts | 1960 | 24 | SFO | fb | 12 | 0 | 73 | 213 | 2 | 30 | 2.9 | 17.8 | 2 |
| 132 | Joe Arenas | 1953 | 28 | SFO | LH | 12 | 0 | 72 | 380 | 6 | 60 | 5.3 | 31.7 | 5 |
| 133 | Jeff Garcia | 2001* | 31 | SFO | QB | 16 | 16 | 72 | 254 | 5 | 25 | 3.5 | 15.9 | 9 |
| 134 | Jeff Garcia | 2000* | 30 | SFO | QB | 16 | 16 | 72 | 414 | 4 | 33 | 5.8 | 25.9 | 7 |
| 135 | Amp Lee | 1993 | 22 | SFO | 15 | 3 | 72 | 230 | 1 | 13 | 3.2 | 15.3 | 1 | |
| 136 | Joe Cribbs | 1987 | 29 | SFO | 11 | 2 | 70 | 300 | 1 | 20 | 4.3 | 27.3 | 1 | |
| 137 | Derek Loville | 1996 | 28 | SFO | rb | 12 | 6 | 70 | 229 | 2 | 16 | 3.3 | 19.1 | 0 |
| 138 | Steve Young | 1998* | 37 | SFO | QB | 15 | 15 | 70 | 454 | 6 | 24 | 6.5 | 30.3 | 9 |
| 139 | Frankie Albert | 1946 | 26 | SFO | QB | 14 | 11 | 69 | -10 | 4 | 0 | -0.1 | -0.7 | 0 |
| 140 | Frankie Albert | 1948 | 28 | SFO | QB | 14 | 9 | 69 | 349 | 8 | 0 | 5.1 | 24.9 | 0 |
| 141 | Sam Cathcart | 1949 | 25 | SFO | 12 | 0 | 69 | 412 | 1 | 57 | 6.0 | 34.3 | 0 | |
| 142 | Verl Lillywhite | 1949 | 23 | SFO | RH | 12 | 3 | 69 | 263 | 2 | 0 | 3.8 | 21.9 | 0 |
| 143 | Steve Young | 1993*+ | 32 | SFO | QB | 16 | 16 | 69 | 407 | 2 | 35 | 5.9 | 25.4 | 8 |
| 144 | Gary Lewis | 1967 | 25 | SFO | 13 | 0 | 67 | 342 | 6 | 52 | 5.1 | 26.3 | 2 | |
| 145 | Verl Lillywhite | 1951 | 25 | SFO | LH | 12 | 0 | 67 | 397 | 1 | 60 | 5.9 | 33.1 | 3 |
| 146 | Forrest Hall | 1948 | 27 | SFO | lh | 14 | 5 | 66 | 413 | 2 | 65 | 6.3 | 29.5 | 0 |
| 147 | Johnny Strzykalski | 1949 | 28 | SFO | 7 | 4 | 66 | 287 | 3 | 44 | 4.3 | 41.0 | 0 | |
| 148 | Steve Young | 1991 | 30 | SFO | QB | 11 | 10 | 66 | 415 | 4 | 21 | 6.3 | 37.7 | 3 |
| 149 | William Floyd | 1995 | 23 | SFO | FB | 8 | 8 | 64 | 237 | 2 | 23 | 3.7 | 29.6 | 1 |
| Rushing | ||||||||||||||
| Rk | Year | Age | Tm | Pos | G | GS | Att | Yds | TD | Lng | Fmb | |||
| 150 | Hugh McElhenny | 1954 | 26 | SFO | RH | 6 | 0 | 64 | 515 | 6 | 60 | 8.0 | 85.8 | 4 |
| 151 | Bill Ring | 1983 | 27 | SFO | fb | 16 | 5 | 64 | 254 | 2 | 25 | 4.0 | 15.9 | 1 |
| 152 | Tom Rathman | 1991 | 29 | SFO | FB | 16 | 16 | 63 | 183 | 6 | 16 | 2.9 | 11.4 | 2 |
| 153 | C.R. Roberts | 1961 | 25 | SFO | FB | 12 | 10 | 63 | 338 | 1 | 54 | 5.4 | 28.2 | 2 |
| 154 | Tom Rathman | 1987 | 25 | SFO | FB | 12 | 7 | 62 | 257 | 1 | 35 | 4.1 | 21.4 | 1 |
| 155 | Joe Montana | 1983* | 27 | SFO | QB | 16 | 16 | 61 | 284 | 2 | 18 | 4.7 | 17.8 | 3 |
| 156 | Paul Hofer | 1980 | 28 | SFO | RB | 6 | 6 | 60 | 293 | 1 | 26 | 4.9 | 48.8 | 0 |
| 157 | Paul Hofer | 1981 | 29 | SFO | 12 | 0 | 60 | 193 | 1 | 12 | 3.2 | 16.1 | 1 | |
| 158 | Maurice Hicks | 2005 | 27 | SFO | RET | 14 | 3 | 59 | 308 | 3 | 73 | 5.2 | 22.0 | 0 |
| 159 | Fred Beasley | 1999 | 25 | SFO | FB | 13 | 11 | 58 | 276 | 4 | 44 | 4.8 | 21.2 | 2 |
| 160 | Marc Logan | 1993 | 28 | SFO | FB | 14 | 12 | 58 | 280 | 7 | 45 | 4.8 | 20.0 | 2 |
| 161 | Tommy Vardell | 1996 | 27 | SFO | fb | 11 | 7 | 58 | 192 | 2 | 17 | 3.3 | 17.5 | 0 |
| 162 | Steve Young | 1994*+ | 33 | SFO | QB | 16 | 16 | 58 | 293 | 7 | 27 | 5.1 | 18.3 | 4 |
| 163 | Tom Rathman | 1992 | 30 | SFO | FB | 15 | 15 | 57 | 194 | 5 | 17 | 3.4 | 12.9 | 1 |
| 164 | Harry Sydney | 1991 | 32 | SFO | 16 | 0 | 57 | 245 | 5 | 32 | 4.3 | 15.3 | 3 | |
| 165 | Jeff Garcia | 2003 | 33 | SFO | QB | 13 | 13 | 56 | 319 | 7 | 21 | 5.7 | 24.5 | 9 |
| 166 | Jimmy Thomas | |||||||||||||