All Matchups, Buffalo Bills vs. Detroit Lions
Buffalo Bills lead series, 7-4-1 (all regular season)
Postseason games noted in bold.
12 Games
| Rk | Date | Day | Tm | Opp | Tm | Opp | |||
|---|---|---|---|---|---|---|---|---|---|
| 1 | 1972-12-10 | Sun | T | Buffalo Bills | Detroit Lions | 21 | 21 | boxscore | |
| 2 | 1976-11-25 | Thu | L | Buffalo Bills | @ | Detroit Lions | 14 | 27 | boxscore |
| 3 | 1979-10-28 | Sun | W | Buffalo Bills | @ | Detroit Lions | 20 | 17 | boxscore |
| 4 | 1991-12-22 | Sun | L | Buffalo Bills | Detroit Lions | 14 | 17 | boxscore | |
| 5 | 1994-11-24 | Thu | L | Buffalo Bills | @ | Detroit Lions | 21 | 35 | boxscore |
| 6 | 1997-10-05 | Sun | W | Buffalo Bills | Detroit Lions | 22 | 13 | boxscore | |
| 7 | 2002-10-27 | Sun | W | Buffalo Bills | Detroit Lions | 24 | 17 | boxscore | |
| 8 | 2006-10-15 | Sun | L | Buffalo Bills | @ | Detroit Lions | 17 | 20 | boxscore |
| 9 | 2010-11-14 | Sun | W | Buffalo Bills | Detroit Lions | 14 | 12 | boxscore | |
| 10 | 2014-10-05 | Sun | W | Buffalo Bills | @ | Detroit Lions | 17 | 14 | boxscore |
| 11 | 2018-12-16 | Sun | W | Buffalo Bills | Detroit Lions | 14 | 13 | boxscore | |
| 12 | 2022-11-24 | Thu | W | Buffalo Bills | @ | Detroit Lions | 28 | 25 | boxscore |
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