Houston Texans lead series, 4-1 (all regular season)
Postseason games noted in bold.
| Rk | Date | Day | Tm | Opp | Tm | Opp | |||
|---|---|---|---|---|---|---|---|---|---|
| 1 | 2004-09-19 | Sun | W | Detroit Lions | Houston Texans | 28 | 16 | boxscore | |
| 2 | 2008-10-19 | Sun | L | Detroit Lions | @ | Houston Texans | 21 | 28 | boxscore |
| 3 | 2012-11-22 | Thu | L | Detroit Lions | Houston Texans | 31 | 34 | boxscore | |
| 4 | 2016-10-30 | Sun | L | Detroit Lions | @ | Houston Texans | 13 | 20 | boxscore |
| 5 | 2020-11-26 | Thu | L | Detroit Lions | Houston Texans | 25 | 41 | boxscore |
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