12 Games
| Rk | Date | Day | Tm | Opp | Tm | Opp | |||
|---|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-11 | Sun | T | Indianapolis Colts | @ | Houston Texans | 20 | 20 | boxscore |
| 2 | 2022-09-18 | Sun | L | Indianapolis Colts | @ | Jacksonville Jaguars | 0 | 24 | boxscore |
| 3 | 2022-09-25 | Sun | W | Indianapolis Colts | Kansas City Chiefs | 20 | 17 | boxscore | |
| 4 | 2022-10-02 | Sun | L | Indianapolis Colts | Tennessee Titans | 17 | 24 | boxscore | |
| 5 | 2022-10-06 | Thu | W | Indianapolis Colts | @ | Denver Broncos | 12 | 9 | boxscore |
| 6 | 2022-10-16 | Sun | W | Indianapolis Colts | Jacksonville Jaguars | 34 | 27 | boxscore | |
| 7 | 2022-10-23 | Sun | L | Indianapolis Colts | @ | Tennessee Titans | 10 | 19 | boxscore |
| 8 | 2022-11-13 | Sun | W | Indianapolis Colts | @ | Las Vegas Raiders | 25 | 20 | boxscore |
| 9 | 2022-11-20 | Sun | L | Indianapolis Colts | Philadelphia Eagles | 16 | 17 | boxscore | |
| 10 | 2022-11-28 | Mon | L | Indianapolis Colts | Pittsburgh Steelers | 17 | 24 | boxscore | |
| 11 | 2022-12-04 | Sun | L | Indianapolis Colts | @ | Dallas Cowboys | 19 | 54 | boxscore |
| 12 | 2022-12-17 | Sat | L | Indianapolis Colts | @ | Minnesota Vikings | 36 | 39 | boxscore |
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