Starters
- *ProBowl, +1st-tm All-Pro
| Pos | Player | Age | Yrs | GS | Summary of Player Stats | Drafted (tm/rnd/yr) |
|---|---|---|---|---|---|---|
| Offensive Starters | ||||||
| QB | EJ Manuel | 23 | Rook | 10 | 180 for 306, 1,972 yards, 11 td, 9 int, & 53 rushes for 186 yards and 2 td | |
| RB | C.J. Spiller | 26 | 3 | 10 | 202 rushes for 933 yards, 2 td, & 33 catches for 185 yards and 0 td | |
| WR | Stevie Johnson | 27 | 5 | 12 | 52 catches for 597 yards, 3 td, & 1 rush for 10 yards and 0 td | |
| WR | Robert Woods | 21 | Rook | 14 | 40 catches for 587 yards, 3 td, & 2 rushes for 16 yards and 0 td | |
| TE | Scott Chandler | 28 | 6 | 7 | 53 catches for 655 yards, 2 td | |
| TE | Lee Smith | 26 | 2 | 14 | 5 catches for 78 yards, 0 td | |
| LT | Cordy Glenn | 24 | 1 | 16 | ||
| LG | Doug Legursky | 27 | 4 | 11 | 1 fumble recovered | |
| C | Eric Wood | 27 | 4 | 16 | ||
| RG | Kraig Urbik | 28 | 3 | 16 | 1 fumble recovered | |
| RT | Erik Pears | 31 | 7 | 16 | ||
| Defensive Starters | ||||||
| LDE | Alan Branch | 29 | 6 | 13 | ||
| LDT | Kyle Williams* | 30 | 7 | 16 | 10.5 sacks, 0 interceptions, 1 fumble recovered | |
| RDT | Marcell Dareus* | 23 | 2 | 14 | 7.5 sacks, 0 interceptions, 0 fumbles recovered | |
| RDE | Mario Williams* | 28 | 7 | 16 | 13.0 sacks, 0 interceptions, 0 fumbles recovered | |
| LLB | Manny Lawson | 29 | 7 | 15 | 4.0 sacks, 1 interception, 1 fumble recovered | |
| MLB | Kiko Alonso | 23 | Rook | 16 | 2.0 sacks, 4 interceptions, 2 fumbles recovered | |
| RLB | Arthur Moats | 25 | 3 | 12 | ||
| LCB | Leodis McKelvin | 28 | 5 | 13 | 0.0 sacks, 1 interception, 4 fumbles recovered | |
| RCB | Stephon Gilmore | 23 | 1 | 9 | 0.0 sacks, 2 interceptions, 1 fumble recovered | |
| SS | Aaron Williams | 23 | 2 | 14 | 0.0 sacks, 4 interceptions, 0 fumbles recovered | |
| FS | Jairus Byrd* | 27 | 4 | 9 | 1.0 sacks, 4 interceptions, 0 fumbles recovered |
Roster