| Offensive Starters | | | | | |
|---|
| QB | Josh Allen | 25 | 3 | 17 | 409 for 646, 4,407 yards, 36 td, 15 int, & 122 rushes for 763 yards and 6 td | |
|---|
| RB | Devin Singletary | 24 | 2 | 16 | 188 rushes for 870 yards, 7 td, & 40 catches for 228 yards and 1 td | |
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| WR | Cole Beasley | 32 | 9 | 8 | 82 catches for 693 yards, 1 td | |
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| WR | Stefon Diggs* | 28 | 6 | 17 | 103 catches for 1,225 yards, 10 td | |
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| WR | Emmanuel Sanders | 34 | 11 | 13 | 42 catches for 626 yards, 4 td, & 2 rushes for 31 yards and 0 td | |
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| TE | Dawson Knox | 25 | 2 | 14 | 49 catches for 587 yards, 9 td | |
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| LT | Dion Dawkins* | 27 | 4 | 15 | | |
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| LG | Ike Boettger | 27 | 3 | 10 | | |
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| C | Mitch Morse | 29 | 6 | 17 | | |
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| RG | Daryl Williams | 29 | 6 | 17 | 1 fumble recovered | |
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| RT | Spencer Brown | 23 | Rook | 10 | 1 fumble recovered | |
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| Defensive Starters | | | | | |
|---|
| LDE | Gregory Rousseau | 21 | Rook | 17 | 4.0 sacks, 1 interception, 0 fumbles recovered | |
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| LDT | Ed Oliver | 24 | 2 | 17 | 4.0 sacks, 0 interceptions, 0 fumbles recovered | |
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| RDT | Star Lotulelei | 32 | 8 | 8 | 3.0 sacks, 0 interceptions, 0 fumbles recovered | |
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| RDE | Jerry Hughes | 33 | 11 | 16 | 2.0 sacks, 0 interceptions, 0 fumbles recovered | |
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| LLB | Matt Milano | 27 | 4 | 16 | 3.0 sacks, 0 interceptions, 2 fumbles recovered | |
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| MLB | Tremaine Edmunds | 23 | 3 | 15 | 0.0 sacks, 1 interception, 0 fumbles recovered | |
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| RLB | Taron Johnson | 25 | 3 | 15 | 3.0 sacks, 1 interception, 0 fumbles recovered | |
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| LCB | Tre'Davious White | 26 | 4 | 11 | 0.5 sacks, 1 interception, 1 fumble recovered | |
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| RCB | Levi Wallace | 26 | 3 | 17 | 0.0 sacks, 2 interceptions, 1 fumble recovered | |
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| SS | Jordan Poyer+ | 30 | 8 | 16 | 3.0 sacks, 5 interceptions, 0 fumbles recovered | |
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| FS | Micah Hyde | 31 | 8 | 17 | 1.0 sacks, 5 interceptions, 2 fumbles recovered | |
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Roster