| Offensive Starters | | | | | |
| QB | Kyle Allen | 23 | 1 | 12 | 303 for 489, 3,322 yards, 17 td, 16 int, & 32 rushes for 106 yards and 2 td | |
| RB | Christian McCaffrey*+ | 23 | 2 | 16 | 287 rushes for 1,387 yards, 15 td, & 116 catches for 1,005 yards and 4 td | |
| WR | D.J. Moore | 22 | 1 | 15 | 87 catches for 1,175 yards, 4 td, & 6 rushes for 40 yards and 0 td | |
| WR | Curtis Samuel | 23 | 2 | 15 | 54 catches for 627 yards, 6 td, & 19 rushes for 130 yards and 1 td | |
| WR | Jarius Wright | 30 | 7 | 9 | 28 catches for 296 yards, 0 td, & 1 rush for -7 yards and 0 td | |
| TE | Greg Olsen | 34 | 12 | 14 | 52 catches for 597 yards, 2 td | |
| LT | Dennis Daley | 23 | Rook | 9 | | |
| LG | Greg Van Roten | 29 | 7 | 11 | 2 fumbles recovered | |
| C | Matt Paradis | 30 | 4 | 16 | | |
| RG | Trai Turner* | 26 | 5 | 13 | | |
| RT | Taylor Moton | 25 | 2 | 16 | | |
| Defensive Starters | | | | | |
| LDE | Gerald McCoy | 31 | 9 | 16 | 5.0 sacks, 0 interceptions, 0 fumbles recovered | |
| NT | Dontari Poe | 29 | 7 | 10 | 4.0 sacks, 0 interceptions, 0 fumbles recovered | |
| RDE | Vernon Butler | 25 | 3 | 9 | 6.0 sacks, 0 interceptions, 0 fumbles recovered | |
| LOLB | Mario Addison | 32 | 8 | 15 | 9.5 sacks, 0 interceptions, 0 fumbles recovered | |
| LILB | Shaq Thompson | 25 | 4 | 14 | 3.0 sacks, 0 interceptions, 0 fumbles recovered | |
| RILB | Luke Kuechly* | 28 | 7 | 16 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | |
| ROLB | Bruce Irvin | 32 | 7 | 12 | 8.5 sacks, 0 interceptions, 1 fumble recovered | |
| LCB | Donte Jackson | 24 | 1 | 10 | 0.0 sacks, 3 interceptions, 2 fumbles recovered | |
| RCB | James Bradberry | 26 | 3 | 15 | 1.0 sacks, 3 interceptions, 0 fumbles recovered | |
| SS | Eric Reid | 28 | 6 | 16 | 4.0 sacks, 0 interceptions, 2 fumbles recovered | |
| FS | Tre Boston | 27 | 5 | 16 | 0.0 sacks, 3 interceptions, 0 fumbles recovered | |
Roster