| Offensive Starters | | | | | |
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| QB | Kyle Allen | 23 | 1 | 12 | 303 for 489, 3,322 yards, 17 td, 16 int, & 32 rushes for 106 yards and 2 td | |
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| RB | Christian McCaffrey*+ | 23 | 2 | 16 | 287 rushes for 1,387 yards, 15 td, & 116 catches for 1,005 yards and 4 td | Carolina Panthers / 1st / 8th pick / 2017 |
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| WR | D.J. Moore | 22 | 1 | 15 | 87 catches for 1,175 yards, 4 td, & 6 rushes for 40 yards and 0 td | Carolina Panthers / 1st / 24th pick / 2018 |
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| WR | Curtis Samuel | 23 | 2 | 15 | 54 catches for 627 yards, 6 td, & 19 rushes for 130 yards and 1 td | Carolina Panthers / 2nd / 40th pick / 2017 |
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| WR | Jarius Wright | 30 | 7 | 9 | 28 catches for 296 yards, 0 td, & 1 rush for -7 yards and 0 td | Minnesota Vikings / 4th / 118th pick / 2012 |
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| TE | Greg Olsen | 34 | 12 | 14 | 52 catches for 597 yards, 2 td | Chicago Bears / 1st / 31st pick / 2007 |
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| LT | Dennis Daley | 23 | Rook | 9 | | Carolina Panthers / 6th / 212th pick / 2019 |
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| T | Daryl Williams | 27 | 4 | 12 | | Carolina Panthers / 4th / 102nd pick / 2015 |
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| LG | Greg Van Roten | 29 | 7 | 11 | 2 fumbles recovered | |
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| G | Trai Turner* | 26 | 5 | 13 | | Carolina Panthers / 3rd / 92nd pick / 2014 |
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| G | Greg Van Roten | 29 | 7 | 11 | | |
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| C | Matt Paradis | 30 | 5 | 16 | | Denver Broncos / 6th / 207th pick / 2014 |
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| RG | Trai Turner* | 26 | 5 | 13 | | Carolina Panthers / 3rd / 92nd pick / 2014 |
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| RT | Taylor Moton | 25 | 2 | 16 | | Carolina Panthers / 2nd / 64th pick / 2017 |
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| Defensive Starters | | | | | |
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| LDE | Gerald McCoy | 31 | 9 | 16 | 5.0 sacks, 0 interceptions, 0 fumbles recovered | Tampa Bay Buccaneers / 1st / 3rd pick / 2010 |
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| DT | Gerald McCoy | 31 | 9 | 16 | | Tampa Bay Buccaneers / 1st / 3rd pick / 2010 |
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| NT | Dontari Poe | 29 | 7 | 10 | 4.0 sacks, 0 interceptions, 0 fumbles recovered | Kansas City Chiefs / 1st / 11th pick / 2012 |
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| RDE | Vernon Butler | 25 | 3 | 9 | 6.0 sacks, 0 interceptions, 0 fumbles recovered | Carolina Panthers / 1st / 30th pick / 2016 |
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| LOLB | Mario Addison | 32 | 8 | 15 | 9.5 sacks, 0 interceptions, 0 fumbles recovered | |
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| LILB | Jermaine Carter Jr. | 24 | 1 | 5 | 0.5 sacks, 0 interceptions, 0 fumbles recovered | Carolina Panthers / 5th / 161st pick / 2018 |
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| LILB | Shaq Thompson | 25 | 4 | 14 | 3.0 sacks, 0 interceptions, 0 fumbles recovered | Carolina Panthers / 1st / 25th pick / 2015 |
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| RILB | Luke Kuechly* | 28 | 7 | 16 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | Carolina Panthers / 1st / 9th pick / 2012 |
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| ROLB | Bruce Irvin | 32 | 7 | 12 | 8.5 sacks, 0 interceptions, 1 fumble recovered | Seattle Seahawks / 1st / 15th pick / 2012 |
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| LCB | Donte Jackson | 24 | 1 | 10 | 0.0 sacks, 3 interceptions, 2 fumbles recovered | Carolina Panthers / 2nd / 55th pick / 2018 |
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| CB | James Bradberry | 26 | 3 | 15 | 1.0 sacks, 3 interceptions, 0 fumbles recovered | Carolina Panthers / 2nd / 62nd pick / 2016 |
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| CB | Ross Cockrell | 28 | 5 | 11 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | Buffalo Bills / 4th / 109th pick / 2014 |
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| RCB | James Bradberry | 26 | 3 | 15 | 1.0 sacks, 3 interceptions, 0 fumbles recovered | Carolina Panthers / 2nd / 62nd pick / 2016 |
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| SS | Eric Reid | 28 | 6 | 16 | 4.0 sacks, 0 interceptions, 2 fumbles recovered | San Francisco 49ers / 1st / 18th pick / 2013 |
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| FS | Tre Boston | 27 | 5 | 16 | 0.0 sacks, 3 interceptions, 0 fumbles recovered | Carolina Panthers / 4th / 128th pick / 2014 |
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Roster