Starters
- *ProBowl, +1st-tm All-Pro
| Pos | Player | Age | Yrs | GS | Summary of Player Stats | Drafted (tm/rnd/yr) |
|---|---|---|---|---|---|---|
| Offensive Starters | ||||||
| QB | Jared Goff* | 31 | 9 | 17 | 393 for 578, 4,564 yards, 34 td, 8 int, & 19 rushes for 45 yards and 0 td | |
| RB | Jahmyr Gibbs* | 23 | 2 | 17 | 243 rushes for 1,223 yards, 13 td, & 77 catches for 616 yards and 5 td | |
| WR | Jameson Williams | 24 | 3 | 15 | 65 catches for 1,117 yards, 7 td, & 6 rushes for 12 yards and 0 td | |
| TE | Sam LaPorta | 24 | 2 | 9 | 40 catches for 489 yards, 3 td | |
| TE | Brock Wright | 27 | 4 | 8 | 14 catches for 108 yards, 2 td | |
| LT | Taylor Decker | 32 | 9 | 14 | ||
| LG | Christian Mahogany | 25 | 1 | 11 | ||
| C | Graham Glasgow | 33 | 9 | 14 | ||
| RG | Tate Ratledge | 24 | Rook | 17 | ||
| RT | Penei Sewell*+ | 25 | 4 | 16 | ||
| Defensive Starters | ||||||
| DL | Alim McNeill | 25 | 4 | 10 | ||
| DL | D.J. Reader | 31 | 9 | 17 | ||
| DL | Tyleik Williams | 22 | Rook | 10 | ||
| DE | Aidan Hutchinson* | 25 | 3 | 17 | 14.5 sacks, 1 interception, 1 fumble recovered | |
| LB | Alex Anzalone | 31 | 8 | 16 | 2.5 sacks, 1 interception, 0 fumbles recovered | |
| LB | Derrick Barnes | 26 | 4 | 17 | 4.0 sacks, 1 interception, 0 fumbles recovered | |
| LB | Jack Campbell*+ | 25 | 2 | 17 | 5.0 sacks, 0 interceptions, 2 fumbles recovered | |
| CB | D.J. Reed | 29 | 7 | 11 | 0.0 sacks, 2 interceptions, 1 fumble recovered | |
| CB | Amik Robertson | 27 | 5 | 10 | 0.0 sacks, 1 interception, 0 fumbles recovered | |
| S | Brian Branch | 24 | 2 | 12 | 2.5 sacks, 0 interceptions, 1 fumble recovered | |
| S | Thomas Harper | 25 | 1 | 9 | 0.0 sacks, 1 interception, 0 fumbles recovered |
Roster