| Offensive Starters | | | | | |
| QB | Brian Hoyer | 30 | 6 | 9 | 224 for 369, 2,606 yards, 19 td, 7 int, & 15 rushes for 44 yards and 0 td | |
| RB | Alfred Blue | 24 | 1 | 9 | 183 rushes for 698 yards, 2 td, & 15 catches for 109 yards and 1 td | |
| WR | DeAndre Hopkins* | 23 | 2 | 16 | 111 catches for 1,521 yards, 11 td | |
| WR | Cecil Shorts | 28 | 4 | 4 | 42 catches for 484 yards, 2 td, & 10 rushes for 47 yards and 0 td | |
| WR | Nate Washington | 32 | 10 | 14 | 47 catches for 658 yards, 4 td | |
| TE | C.J. Fiedorowicz | 24 | 1 | 14 | 17 catches for 167 yards, 1 td | |
| LT | Duane Brown | 30 | 7 | 14 | | |
| LG | Xavier Su'a-Filo | 24 | 1 | 9 | 1 fumble recovered | |
| C | Ben Jones | 26 | 3 | 16 | | |
| RG | Brandon Brooks | 26 | 3 | 14 | | |
| RT | Derek Newton | 28 | 4 | 16 | 2 fumbles recovered | |
| Defensive Starters | | | | | |
| LDE | Jared Crick | 26 | 3 | 16 | 2.0 sacks, 0 interceptions, 2 fumbles recovered | |
| NT | Vince Wilfork | 34 | 11 | 16 | | |
| RDE | J.J. Watt*+ | 26 | 4 | 16 | 17.5 sacks, 0 interceptions, 1 fumble recovered | |
| LOLB | Whitney Mercilus | 25 | 3 | 10 | 12.0 sacks, 0 interceptions, 2 fumbles recovered | |
| LILB | Brian Cushing | 28 | 6 | 16 | | |
| RILB | Benardrick McKinney | 23 | Rook | 11 | 1.0 sacks, 0 interceptions, 0 fumbles recovered | |
| ROLB | Jadeveon Clowney | 22 | 1 | 9 | 4.5 sacks, 0 interceptions, 0 fumbles recovered | |
| LCB | Kareem Jackson | 27 | 5 | 10 | 0.0 sacks, 2 interceptions, 1 fumble recovered | |
| RCB | Johnathan Joseph | 31 | 9 | 16 | 0.0 sacks, 1 interception, 1 fumble recovered | |
| SS | Quintin Demps | 30 | 7 | 13 | 0.5 sacks, 1 interception, 2 fumbles recovered | |
| FS | Andre Hal | 23 | 1 | 11 | 0.0 sacks, 4 interceptions, 0 fumbles recovered | |
Roster