- March 23, 2022: Traded Tyreek Hill to Dolphins for 2022 1st round pick (29th overall subsequently traded , Cole Strange), 2022 2nd round pick (50th overall subsequently traded , Tyquan Thornton), 2022 4th round pick (121st overall subsequently traded , Jack Jones), 2023 4th round pick (122nd overall subsequently traded , Jon Gaines) and 2023 6th round pick (178th overall subsequently traded , Eric Scott)
- April 28, 2022: Traded 2022 1st round pick (29th overall, Cole Strange), 2022 3rd round pick (94th overall subsequently traded , Matt Corral) and 2022 4th round pick (121st overall, Jack Jones) to Patriots for 2022 1st round pick (21st overall, Trent McDuffie)
- April 29, 2022: Traded 2022 2nd round pick (50th overall, Tyquan Thornton) to Patriots for 2022 2nd round pick (54th overall, Skyy Moore) and 2022 5th round pick (158th overall subsequently traded , Tyreke Smith)
- April 30, 2022: Traded 2022 5th round pick (158th overall, Tyreke Smith) and 2022 7th round pick (233rd overall, Dareke Young) to Seahawks for 2022 5th round pick (145th overall, Darian Kinnard)
- May 2, 2022: Traded a conditional 2024 pick (7th round) to Texans for Lonnie Johnson Jr.
- October 27, 2022: Traded 2023 3rd round pick (100th overall subsequently traded , Tre Tucker) and 2023 6th round pick (209th overall, Tre Hawkins) to Giants for Kadarius Toney
- November 1, 2022: Traded Rashad Fenton to Falcons for a conditional 2023 pick (7th round; not conveyed)