| Offensive Starters | | | | | |
| QB | Patrick Mahomes | 30 | 8 | 14 | 315 for 502, 3,587 yards, 22 td, 11 int, & 64 rushes for 422 yards and 5 td | |
| RB | Isiah Pacheco | 26 | 3 | 12 | 118 rushes for 462 yards, 1 td, & 19 catches for 101 yards and 1 td | |
| WR | Rashee Rice | 25 | 2 | 8 | 53 catches for 571 yards, 5 td, & 5 rushes for 20 yards and 1 td | |
| WR | JuJu Smith-Schuster | 29 | 8 | 12 | 33 catches for 345 yards, 1 td | |
| WR | Xavier Worthy | 22 | 1 | 13 | 42 catches for 532 yards, 1 td, & 11 rushes for 87 yards and 0 td | |
| TE | Travis Kelce* | 36 | 12 | 17 | 76 catches for 851 yards, 5 td, & 1 rush for 1 yards and 0 td | |
| LT | Josh Simmons | 23 | Rook | 8 | | |
| LG | Kingsley Suamataia | 22 | 1 | 17 | | |
| C | Creed Humphrey*+ | 26 | 4 | 17 | | |
| RG | Trey Smith* | 26 | 4 | 12 | 1 fumble recovered | |
| RT | Jawaan Taylor | 28 | 6 | 12 | | |
| Defensive Starters | | | | | |
| DE | Michael Danna | 28 | 5 | 14 | 1.0 sacks, 1 interception, 0 fumbles recovered | |
| DE | George Karlaftis III | 24 | 3 | 15 | 6.0 sacks, 0 interceptions, 1 fumble recovered | |
| DT | Chris Jones* | 31 | 9 | 17 | 7.0 sacks, 0 interceptions, 0 fumbles recovered | |
| DT | Derrick Nnadi | 29 | 7 | 11 | | |
| LB | Nick Bolton | 25 | 4 | 17 | 1.0 sacks, 1 interception, 0 fumbles recovered | |
| LB | Leo Chenal | 25 | 3 | 12 | 2.0 sacks, 1 interception, 0 fumbles recovered | |
| LB | Drue Tranquill | 30 | 6 | 17 | 2.0 sacks, 0 interceptions, 1 fumble recovered | |
| CB | Trent McDuffie | 25 | 3 | 13 | 1.0 sacks, 1 interception, 0 fumbles recovered | |
| CB | Jaylen Watson | 27 | 3 | 15 | 2.0 sacks, 2 interceptions, 0 fumbles recovered | |
| S | Chamarri Conner | 25 | 2 | 17 | 2.0 sacks, 1 interception, 0 fumbles recovered | |
| S | Bryan Cook | 26 | 3 | 17 | | |
Roster