Starters
- *ProBowl, +1st-tm All-Pro
| Pos | Player | Age | Yrs | GS | Summary of Player Stats | Drafted (tm/rnd/yr) |
|---|---|---|---|---|---|---|
| Offensive Starters | ||||||
| QB | Mac Jones | 25 | 2 | 11 | 224 for 345, 2,120 yards, 10 td, 12 int, & 26 rushes for 96 yards and 0 td | |
| RB | Rhamondre Stevenson | 25 | 2 | 12 | 156 rushes for 619 yards, 4 td, & 38 catches for 238 yards and 0 td | |
| WR | Kendrick Bourne | 28 | 6 | 5 | 37 catches for 406 yards, 4 td, & 1 rush for 4 yards and 0 td | |
| WR | DeVante Parker | 30 | 8 | 13 | 33 catches for 394 yards, 0 td | |
| TE | Pharaoh Brown | 29 | 6 | 11 | 13 catches for 208 yards, 1 td | |
| TE | Mike Gesicki | 28 | 5 | 10 | 29 catches for 244 yards, 2 td | |
| LT | Trent Brown | 30 | 8 | 8 | ||
| LG | Cole Strange | 25 | 1 | 10 | 1 fumble recovered | |
| C | David Andrews | 31 | 8 | 17 | 1 fumble recovered | |
| RG | Sidy Sow | 25 | Rook | 13 | ||
| RT | Michael Onwenu | 26 | 3 | 15 | ||
| Defensive Starters | ||||||
| LDE | Deatrich Wise Jr. | 29 | 6 | 13 | 4.5 sacks, 0 interceptions, 0 fumbles recovered | |
| NT | Davon Godchaux | 29 | 6 | 17 | 0.0 sacks, 0 interceptions, 1 fumble recovered | |
| RDE | Lawrence Guy | 33 | 11 | 12 | ||
| LILB | Ja'Whaun Bentley | 27 | 5 | 16 | 4.5 sacks, 0 interceptions, 0 fumbles recovered | |
| RILB | Jahlani Tavai | 27 | 4 | 16 | 1.0 sacks, 2 interceptions, 0 fumbles recovered | |
| ROLB | Anfernee Jennings | 26 | 3 | 14 | 1.5 sacks, 0 interceptions, 1 fumble recovered | |
| LCB | Jonathan Jones | 30 | 7 | 14 | ||
| RCB | J.C. Jackson | 28 | 5 | 6 | ||
| SS | Jabrill Peppers | 28 | 6 | 15 | 1.0 sacks, 2 interceptions, 1 fumble recovered | |
| FS | Kyle Dugger | 27 | 3 | 17 | 1.5 sacks, 2 interceptions, 0 fumbles recovered | |
| DB | Jalen Mills | 29 | 7 | 8 |

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