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- March 14, 2018: Traded 2018 4th round pick (135th overall, John Franklin-Myers) and 2018 6th round pick (176th overall, John Kelly) to Rams for Alec Ogletree and 2019 7th round pick (245th overall, Chris Slayton)
- March 22, 2018: Traded Jason Pierre-Paul and 2018 4th round pick (102nd overall subsequently traded, Jalyn Holmes) to Buccaneers for 2018 4th round pick (108th overall, Kyle Lauletta) and 2018 3rd round pick (69th overall, B.J. Hill)
- April 23, 2018: Traded 2019 7th round pick (220th overall subsequently traded, Cullen Gillaspia) to Broncos for Riley Dixon
- August 27, 2018: Traded Brett Jones to Vikings for 2019 7th round pick (232nd overall, George Asafo-Adjei)
- October 23, 2018: Traded Eli Apple to Saints for 2019 4th round pick (132nd overall subsequently traded, Ugochukwu Amadi) and a 2020 7th round pick
- October 25, 2018: Traded Damon Harrison to Lions for 2019 5th round pick (142nd overall subsequently traded, Ben Burr-Kirven)