| Rk | Day | Date | Tm | Opp | Tm | Opp | |||
|---|---|---|---|---|---|---|---|---|---|
| 1 | Sun | September 12, 1999 | L | Carolina Panthers | @ | New Orleans Saints | 10 | 19 | box |
| 2 | Sun | September 19, 1999 | L | Carolina Panthers | Jacksonville Jaguars | 20 | 22 | box | |
| 3 | Sun | September 26, 1999 | W | Carolina Panthers | Cincinnati Bengals | 27 | 3 | box | |
| 4 | Sun | October 3, 1999 | L | Carolina Panthers | @ | Washington Redskins | 36 | 38 | box |
| 5 | Sun | October 17, 1999 | W | Carolina Panthers | @ | San Francisco 49ers | 31 | 29 | box |
| 6 | Sun | October 24, 1999 | L | Carolina Panthers | Detroit Lions | 9 | 24 | box | |
| 7 | Sun | October 31, 1999 | L | Carolina Panthers | @ | Atlanta Falcons | 20 | 27 | box |
| 8 | Sun | November 7, 1999 | W | Carolina Panthers | Philadelphia Eagles | 33 | 7 | box | |
| 9 | Sun | November 14, 1999 | L | Carolina Panthers | @ | St. Louis Rams | 10 | 35 | box |
| 10 | Sun | November 21, 1999 | W | Carolina Panthers | @ | Cleveland Browns | 31 | 17 | box |
| 11 | Sun | November 28, 1999 | W | Carolina Panthers | Atlanta Falcons | 34 | 28 | box | |
| 12 | Sun | December 5, 1999 | L | Carolina Panthers | St. Louis Rams | 21 | 34 | box | |
| 13 | Sun | December 12, 1999 | W | Carolina Panthers | @ | Green Bay Packers | 33 | 31 | box |
| 14 | Sat | December 18, 1999 | W | Carolina Panthers | San Francisco 49ers | 41 | 24 | box | |
| 15 | Sun | December 26, 1999 | L | Carolina Panthers | @ | Pittsburgh Steelers | 20 | 30 | box |
| 16 | Sun | January 2, 2000 | W | Carolina Panthers | New Orleans Saints | 45 | 13 | box |