All Matchups, Carolina Panthers vs. Buffalo Bills
Buffalo Bills lead series, 7-2 (all regular season)
Postseason games noted in bold.
9 Games
| Rk | Date | Day | Tm | Opp | Tm | Opp | |||
|---|---|---|---|---|---|---|---|---|---|
| 1 | 1995-09-10 | Sun | L | Carolina Panthers | @ | Buffalo Bills | 9 | 31 | boxscore |
| 2 | 1998-10-25 | Sun | L | Carolina Panthers | Buffalo Bills | 14 | 30 | boxscore | |
| 3 | 2001-12-09 | Sun | L | Carolina Panthers | @ | Buffalo Bills | 24 | 25 | boxscore |
| 4 | 2005-11-27 | Sun | W | Carolina Panthers | @ | Buffalo Bills | 13 | 9 | boxscore |
| 5 | 2009-10-25 | Sun | L | Carolina Panthers | Buffalo Bills | 9 | 20 | boxscore | |
| 6 | 2013-09-15 | Sun | L | Carolina Panthers | @ | Buffalo Bills | 23 | 24 | boxscore |
| 7 | 2017-09-17 | Sun | W | Carolina Panthers | Buffalo Bills | 9 | 3 | boxscore | |
| 8 | 2021-12-19 | Sun | L | Carolina Panthers | @ | Buffalo Bills | 14 | 31 | boxscore |
| 9 | 2025-10-26 | Sun | L | Carolina Panthers | Buffalo Bills | 9 | 40 | boxscore |
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