All Matchups, Detroit Lions vs. Buffalo Bills
Buffalo Bills lead series, 7-4-1 (all regular season)
Postseason games noted in bold.
12 Games
| Rk | Date | Day | Tm | Opp | Tm | Opp | |||
|---|---|---|---|---|---|---|---|---|---|
| 1 | 1972-12-10 | Sun | T | Detroit Lions | @ | Buffalo Bills | 21 | 21 | boxscore |
| 2 | 1976-11-25 | Thu | W | Detroit Lions | Buffalo Bills | 27 | 14 | boxscore | |
| 3 | 1979-10-28 | Sun | L | Detroit Lions | Buffalo Bills | 17 | 20 | boxscore | |
| 4 | 1991-12-22 | Sun | W | Detroit Lions | @ | Buffalo Bills | 17 | 14 | boxscore |
| 5 | 1994-11-24 | Thu | W | Detroit Lions | Buffalo Bills | 35 | 21 | boxscore | |
| 6 | 1997-10-05 | Sun | L | Detroit Lions | @ | Buffalo Bills | 13 | 22 | boxscore |
| 7 | 2002-10-27 | Sun | L | Detroit Lions | @ | Buffalo Bills | 17 | 24 | boxscore |
| 8 | 2006-10-15 | Sun | W | Detroit Lions | Buffalo Bills | 20 | 17 | boxscore | |
| 9 | 2010-11-14 | Sun | L | Detroit Lions | @ | Buffalo Bills | 12 | 14 | boxscore |
| 10 | 2014-10-05 | Sun | L | Detroit Lions | Buffalo Bills | 14 | 17 | boxscore | |
| 11 | 2018-12-16 | Sun | L | Detroit Lions | @ | Buffalo Bills | 13 | 14 | boxscore |
| 12 | 2022-11-24 | Thu | L | Detroit Lions | Buffalo Bills | 25 | 28 | boxscore |
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