| Offensive Starters | | | | | |
|---|
| QB | Carson Palmer | 34 | 9 | 16 | 362 for 572, 4,274 yards, 24 td, 22 int, & 27 rushes for 3 yards and 0 td | |
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| RB | Rashard Mendenhall | 26 | 5 | 15 | 217 rushes for 687 yards, 8 td, & 18 catches for 134 yards and 0 td | |
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| WR | Larry Fitzgerald* | 30 | 9 | 16 | 82 catches for 954 yards, 10 td, & 2 rushes for 8 yards and 0 td | |
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| WR | Michael Floyd | 24 | 1 | 16 | 65 catches for 1,041 yards, 5 td | |
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| TE | Jim Dray | 27 | 3 | 15 | 26 catches for 215 yards, 2 td | |
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| TE | Rob Housler | 25 | 2 | 10 | 39 catches for 454 yards, 1 td | |
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| LT | Bradley Sowell | 24 | 1 | 12 | | |
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| LG | Daryn Colledge | 31 | 7 | 16 | 1 fumble recovered | |
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| C | Lyle Sendlein | 29 | 6 | 16 | 1 fumble recovered | |
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| RG | Paul Fanaika | 27 | 2 | 16 | | |
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| RT | Eric Winston | 30 | 7 | 16 | | |
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| Defensive Starters | | | | | |
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| LDE | Calais Campbell | 27 | 5 | 16 | 9.0 sacks, 0 interceptions, 2 fumbles recovered | |
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| NT | Dan Williams | 26 | 3 | 10 | 1.0 sacks, 1 interception, 0 fumbles recovered | |
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| RDE | Darnell Dockett | 32 | 9 | 16 | 4.5 sacks, 0 interceptions, 0 fumbles recovered | |
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| LOLB | Matt Shaughnessy | 27 | 4 | 12 | 3.0 sacks, 0 interceptions, 3 fumbles recovered | |
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| LILB | Daryl Washington | 27 | 3 | 12 | 3.0 sacks, 2 interceptions, 1 fumble recovered | |
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| RILB | Karlos Dansby | 32 | 9 | 16 | 6.5 sacks, 4 interceptions, 1 fumble recovered | |
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| ROLB | John Abraham* | 35 | 13 | 13 | 11.5 sacks, 0 interceptions, 0 fumbles recovered | |
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| LCB | Patrick Peterson*+ | 23 | 2 | 16 | 0.0 sacks, 3 interceptions, 2 fumbles recovered | |
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| RCB | Jerraud Powers | 26 | 4 | 16 | 0.0 sacks, 1 interception, 0 fumbles recovered | |
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| SS | Yeremiah Bell | 35 | 9 | 16 | 1.0 sacks, 2 interceptions, 0 fumbles recovered | |
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| FS | Tyrann Mathieu | 21 | Rook | 11 | 1.0 sacks, 2 interceptions, 0 fumbles recovered | |
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Roster