| Single-season | Passing | Rushing | Receiving | Returns | Kicking | Scoring | |
| Career | Passing | Rushing | Receiving | Returns | Kicking | Scoring | Defense |
| Rushing | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rk | Year | Age | Tm | Pos | G | GS | Att | Yds | TD | Lng | Fmb | |||
| 1 | Eddie George | 2000*+ | 27 | TEN | RB | 16 | 16 | 403 | 1509 | 14 | 35 | 3.7 | 94.3 | 5 |
| 2 | Earl Campbell | 1980*+ | 25 | HOU | RB | 15 | 15 | 373 | 1934 | 13 | 55 | 5.2 | 128.9 | 4 |
| 3 | Earl Campbell | 1979*+ | 24 | HOU | RB | 16 | 16 | 368 | 1697 | 19 | 61 | 4.6 | 106.1 | 8 |
| 4 | Earl Campbell | 1981* | 26 | HOU | RB | 16 | 16 | 361 | 1376 | 10 | 43 | 3.8 | 86.0 | 10 |
| 5 | Eddie George | 1997* | 24 | TEN | RB | 16 | 16 | 357 | 1399 | 6 | 30 | 3.9 | 87.4 | 4 |
| 6 | Eddie George | 1998* | 25 | TEN | RB | 16 | 16 | 348 | 1294 | 5 | 37 | 3.7 | 80.9 | 7 |
| 7 | Eddie George | 2002 | 29 | TEN | RB | 16 | 16 | 343 | 1165 | 12 | 35 | 3.4 | 72.8 | 1 |
| 8 | Eddie George | 1996 | 23 | HOU | RB | 16 | 16 | 335 | 1368 | 8 | 76 | 4.1 | 85.5 | 3 |
| 9 | Earl Campbell | 1983* | 28 | HOU | RB | 14 | 14 | 322 | 1301 | 12 | 42 | 4.0 | 92.9 | 4 |
| 10 | Eddie George | 1999* | 26 | TEN | RB | 16 | 16 | 320 | 1304 | 9 | 40 | 4.1 | 81.5 | 5 |
| 11 | Eddie George | 2001 | 28 | TEN | RB | 16 | 16 | 315 | 939 | 5 | 27 | 3.0 | 58.7 | 8 |
| 12 | Eddie George | 2003 | 30 | TEN | RB | 16 | 16 | 312 | 1031 | 5 | 27 | 3.3 | 64.4 | 1 |
| 13 | LenDale White | 2007 | 23 | TEN | RB | 16 | 16 | 303 | 1110 | 7 | 28 | 3.7 | 69.4 | 5 |
| 14 | Earl Campbell | 1978*+ | 23 | HOU | RB | 15 | 14 | 302 | 1450 | 13 | 81 | 4.8 | 96.7 | 9 |
| 15 | Travis Henry | 2006 | 28 | TEN | RB | 14 | 13 | 270 | 1211 | 7 | 70 | 4.5 | 86.5 | 3 |
| 16 | Lorenzo White | 1992* | 26 | HOU | RB | 16 | 16 | 265 | 1226 | 7 | 44 | 4.6 | 76.6 | 2 |
| 17 | Mike Rozier | 1988* | 27 | HOU | RB | 15 | 14 | 251 | 1002 | 10 | 28 | 4.0 | 66.8 | 7 |
| 18 | Rodney Thomas | 1995 | 22 | HOU | RB | 16 | 10 | 251 | 947 | 5 | 74 | 3.8 | 59.2 | 8 |
| 19 | Charley Tolar | 1962* | 25 | HOU | FB | 14 | 0 | 244 | 1012 | 7 | 25 | 4.1 | 72.3 | 7 |
| 20 | Hoyle Granger | 1967* | 23 | HOU | FB | 14 | 0 | 236 | 1194 | 6 | 67 | 5.1 | 85.3 | 1 |
| 21 | Mike Rozier | 1987* | 26 | HOU | RB | 11 | 11 | 229 | 957 | 3 | 41 | 4.2 | 87.0 | 5 |
| 22 | Chris Brown | 2005 | 24 | TEN | RB | 15 | 14 | 224 | 851 | 5 | 38 | 3.8 | 56.7 | 4 |
| 23 | Chris Brown | 2004 | 23 | TEN | RB | 11 | 11 | 220 | 1067 | 6 | 52 | 4.9 | 97.0 | 6 |
| 24 | Hoyle Granger | 1968* | 24 | HOU | FB | 13 | 0 | 202 | 848 | 7 | 47 | 4.2 | 65.2 | 3 |
| 25 | Billy Cannon | 1961*+ | 24 | HOU | HB | 14 | 0 | 200 | 948 | 6 | 61 | 4.7 | 67.7 | 5 |
| 26 | Mike Rozier | 1986 | 25 | HOU | RB | 13 | 13 | 199 | 662 | 4 | 19 | 3.3 | 50.9 | 6 |
| 27 | Gary Brown | 1993 | 24 | HOU | RB | 16 | 8 | 195 | 1002 | 6 | 26 | 5.1 | 62.6 | 4 |
| 28 | Charley Tolar | 1963 | 26 | HOU | FB | 14 | 0 | 194 | 659 | 3 | 33 | 3.4 | 47.1 | 8 |
| 29 | Lorenzo White | 1994 | 28 | HOU | RB | 15 | 8 | 191 | 757 | 3 | 33 | 4.0 | 50.5 | 2 |
| Rushing | ||||||||||||||
| Rk | Year | Age | Tm | Pos | G | GS | Att | Yds | TD | Lng | Fmb | |||
| 30 | Larry Moriarty | 1984 | 26 | HOU | RB | 14 | 9 | 189 | 785 | 6 | 51 | 4.2 | 56.1 | 5 |
| 31 | Hoyle Granger | 1969 | 25 | HOU | FB | 13 | 0 | 186 | 740 | 3 | 23 | 4.0 | 56.9 | 1 |
| 32 | Ronnie Coleman | 1977 | 26 | HOU | RB | 14 | 0 | 185 | 660 | 5 | 22 | 3.6 | 47.1 | 7 |
| 33 | Ronnie Coleman | 1975 | 24 | HOU | RB | 14 | 0 | 175 | 790 | 5 | 46 | 4.5 | 56.4 | 6 |
| 34 | Ronnie Coleman | 1976 | 25 | HOU | RB | 13 | 0 | 171 | 684 | 2 | 39 | 4.0 | 52.6 | 8 |
| 35 | Allen Pinkett | 1991 | 27 | HOU | RB | 16 | 16 | 171 | 720 | 9 | 32 | 4.2 | 45.0 | 2 |
| 36 | Fred Willis | 1973 | 26 | HOU | FB | 14 | 0 | 171 | 579 | 4 | 25 | 3.4 | 41.4 | 5 |
| 37 | Gary Brown | 1994 | 25 | HOU | rb | 12 | 8 | 169 | 648 | 4 | 18 | 3.8 | 54.0 | 6 |
| 38 | Lorenzo White | 1990 | 24 | HOU | RB | 16 | 16 | 168 | 702 | 8 | 22 | 4.2 | 43.9 | 7 |
| 39 | Don Hardeman | 1975 | 23 | HOU | FB | 13 | 0 | 166 | 648 | 5 | 39 | 3.9 | 49.8 | 3 |
| 40 | Earl Campbell | 1982 | 27 | HOU | RB | 9 | 9 | 157 | 538 | 2 | 22 | 3.4 | 59.8 | 2 |
| 41 | Charley Tolar | 1961* | 24 | HOU | FB | 14 | 0 | 157 | 577 | 4 | 28 | 3.7 | 41.2 | 3 |
| 42 | Dave Smith | 1960+ | 23 | HOU | FB | 14 | 14 | 154 | 643 | 5 | 65 | 4.2 | 45.9 | 4 |
| 43 | Billy Cannon | 1960 | 23 | HOU | HB | 14 | 0 | 152 | 644 | 1 | 39 | 4.2 | 46.0 | 3 |
| 44 | Fred Willis | 1976 | 29 | HOU | FB | 13 | 0 | 148 | 542 | 2 | 44 | 3.7 | 41.7 | 3 |
| 45 | Billy Cannon | 1962 | 25 | HOU | HB | 14 | 0 | 147 | 474 | 7 | 64 | 3.2 | 33.9 | 5 |
| 46 | Sid Blanks | 1964* | 24 | HOU | HB | 14 | 0 | 145 | 756 | 6 | 91 | 5.2 | 54.0 | 5 |
| 47 | Rob Carpenter | 1977 | 22 | HOU | FB | 11 | 7 | 144 | 652 | 1 | 77 | 4.5 | 59.3 | 3 |
| 48 | Charley Tolar | 1964 | 27 | HOU | FB | 14 | 0 | 139 | 515 | 4 | 40 | 3.7 | 36.8 | 2 |
| 49 | Antowain Smith | 2004 | 32 | TEN | 13 | 4 | 137 | 509 | 4 | 43 | 3.7 | 39.2 | 2 | |
| 50 | Mike Rozier | 1985 | 24 | HOU | fb | 14 | 6 | 133 | 462 | 8 | 30 | 3.5 | 33.0 | 3 |
| 51 | Roy Hopkins | 1969 | 24 | HOU | HB | 14 | 0 | 131 | 473 | 4 | 43 | 3.6 | 33.8 | 2 |
| 52 | Lorenzo White | 1993 | 27 | HOU | rb | 8 | 8 | 131 | 465 | 2 | 14 | 3.5 | 58.1 | 1 |
| 53 | Ode Burrell | 1965* | 26 | HOU | HB | 14 | 0 | 130 | 528 | 3 | 63 | 4.1 | 37.7 | 6 |
| 54 | Alonzo Highsmith | 1989 | 24 | HOU | FB | 16 | 16 | 128 | 531 | 4 | 25 | 4.1 | 33.2 | 6 |
| 55 | Tim Wilson | 1978 | 24 | HOU | FB | 16 | 13 | 126 | 431 | 0 | 24 | 3.4 | 26.9 | 5 |
| 56 | Joe Dawkins | 1970 | 22 | HOU | FB | 14 | 0 | 124 | 517 | 2 | 49 | 4.2 | 36.9 | 4 |
| 57 | Ode Burrell | 1966 | 27 | HOU | HB | 14 | 0 | 122 | 406 | 0 | 45 | 3.3 | 29.0 | 3 |
| 58 | Allen Pinkett | 1988 | 24 | HOU | 16 | 2 | 122 | 513 | 7 | 27 | 4.2 | 32.1 | 2 | |
| 59 | Willie Rodgers | 1974 | 25 | HOU | FB | 14 | 0 | 122 | 413 | 5 | 20 | 3.4 | 29.5 | 5 |
| Rushing | ||||||||||||||
| Rk | Year | Age | Tm | Pos | G | GS | Att | Yds | TD | Lng | Fmb | |||
| 60 | Fred Willis | 1975 | 28 | HOU | 13 | 0 | 118 | 420 | 2 | 23 | 3.6 | 32.3 | 7 | |
| 61 | Woody Campbell | 1968 | 24 | HOU | hb | 14 | 0 | 115 | 436 | 6 | 37 | 3.8 | 31.1 | 4 |
| 62 | Woody Campbell | 1967* | 23 | HOU | HB | 14 | 0 | 110 | 511 | 4 | 42 | 4.6 | 36.5 | 0 |
| 63 | Lorenzo White | 1991 | 25 | HOU | 13 | 0 | 110 | 465 | 4 | 20 | 4.2 | 35.8 | 3 | |
| 64 | Larry Moriarty | 1985 | 27 | HOU | FB | 15 | 12 | 106 | 381 | 3 | 18 | 3.6 | 25.4 | 2 |
| 65 | Bob Gresham | 1973 | 25 | HOU | RB | 13 | 0 | 104 | 400 | 2 | 52 | 3.8 | 30.8 | 5 |
| 66 | Lorenzo White | 1989 | 23 | HOU | 16 | 0 | 104 | 349 | 5 | 33 | 3.4 | 21.8 | 2 | |
| 67 | Mike Richardson | 1970 | 24 | HOU | RB | 14 | 0 | 103 | 368 | 2 | 34 | 3.6 | 26.3 | 2 |
| 68 | Butch Woolfolk | 1985 | 25 | HOU | RB | 16 | 14 | 103 | 392 | 1 | 43 | 3.8 | 24.5 | 5 |
| 69 | Chris Brown | 2007 | 26 | TEN | 12 | 1 | 102 | 462 | 5 | 42 | 4.5 | 38.5 | 1 | |
| 70 | Steve McNair | 1997 | 24 | TEN | QB | 16 | 16 | 101 | 674 | 8 | 47 | 6.7 | 42.1 | 16 |
| 71 | Tim Wilson | 1977 | 23 | HOU | fb | 10 | 5 | 99 | 343 | 3 | 16 | 3.5 | 34.3 | 1 |
| 72 | Rob Carpenter | 1980 | 25 | HOU | 15 | 1 | 97 | 359 | 3 | 46 | 3.7 | 23.9 | 4 | |
| 73 | Earl Campbell | 1984 | 29 | HOU | rb | 6 | 6 | 96 | 278 | 4 | 22 | 2.9 | 46.3 | 2 |
| 74 | Woody Campbell | 1971 | 27 | HOU | RB | 12 | 0 | 96 | 259 | 1 | 18 | 2.7 | 21.6 | 0 |
| 75 | Alonzo Highsmith | 1988 | 23 | HOU | FB | 16 | 16 | 94 | 466 | 2 | 42 | 5.0 | 29.1 | 7 |
| 76 | Allen Pinkett | 1989 | 25 | HOU | rb | 16 | 6 | 94 | 449 | 1 | 60 | 4.8 | 28.1 | 1 |
| 77 | Vince Young | 2007 | 24 | TEN | QB | 15 | 15 | 93 | 395 | 3 | 21 | 4.2 | 26.3 | 10 |
| 78 | Rob Carpenter | 1979 | 24 | HOU | 16 | 0 | 92 | 355 | 3 | 13 | 3.9 | 22.2 | 3 | |
| 79 | Fred Willis | 1972 | 25 | HOU | FB | 8 | 0 | 92 | 334 | 0 | 43 | 3.6 | 41.8 | 2 |
| 80 | Robert Holmes | 1971 | 26 | HOU | FB | 8 | 0 | 91 | 288 | 4 | 31 | 3.2 | 36.0 | 7 |
| 81 | Travis Henry | 2005 | 27 | TEN | 9 | 1 | 88 | 335 | 0 | 29 | 3.8 | 37.2 | 2 | |
| 82 | Mike Rozier | 1989 | 28 | HOU | RB | 12 | 10 | 88 | 301 | 2 | 17 | 3.4 | 25.1 | 4 |
| 83 | Gary Brown | 1995 | 26 | HOU | 10 | 4 | 86 | 293 | 0 | 21 | 3.4 | 29.3 | 2 | |
| 84 | Paul Robinson | 1972 | 28 | HOU | RB | 8 | 0 | 86 | 355 | 3 | 30 | 4.1 | 44.4 | 0 |
| 85 | Chris Johnson | 2008 | 23 | TEN | 5 | 85 | 381 | 2 | 51 | 4.5 | 76.2 | 0 | ||
| 86 | Tim Wilson | 1979 | 25 | HOU | FB | 16 | 16 | 84 | 319 | 2 | 19 | 3.8 | 19.9 | 2 |
| 87 | Vince Young | 2006* | 23 | TEN | QB | 15 | 13 | 83 | 552 | 7 | 39 | 6.7 | 36.8 | 12 |
| 88 | Rob Carpenter | 1978 | 23 | HOU | 11 | 0 | 82 | 348 | 5 | 20 | 4.2 | 31.6 | 0 | |
| 89 | Steve McNair | 2002 | 29 | TEN | QB | 16 | 16 | 82 | 440 | 3 | 26 | 5.4 | 27.5 | 9 |
| Rushing | ||||||||||||||
| Rk | Year | Age | Tm | Pos | G | GS | Att | Yds | TD | Lng | Fmb | |||
| 90 | Steve McNair | 1998 | 25 | TEN | QB | 16 | 16 | 77 | 559 | 4 | 71 | 7.3 | 34.9 | 5 |
| 91 | Allen Pinkett | 1986 | 22 | HOU | RET | 16 | 3 | 77 | 225 | 2 | 14 | 2.9 | 14.1 | 2 |
| 92 | Steve McNair | 2001 | 28 | TEN | QB | 15 | 15 | 75 | 414 | 5 | 24 | 5.5 | 27.6 | 5 |
| 93 | Bill Tobin | 1963 | 22 | HOU | HB | 10 | 0 | 75 | 271 | 4 | 32 | 3.6 | 27.1 | 3 |
| 94 | Vic Washington | 1974 | 28 | HOU | RB | 12 | 0 | 74 | 281 | 2 | 23 | 3.8 | 23.4 | 4 |
| 95 | Fred Willis | 1974 | 27 | HOU | 10 | 0 | 74 | 239 | 3 | 18 | 3.2 | 23.9 | 0 | |
| 96 | Charley Tolar | 1965 | 28 | HOU | FB | 11 | 0 | 73 | 230 | 0 | 18 | 3.2 | 20.9 | 0 |
| 97 | Steve McNair | 2000* | 27 | TEN | QB | 16 | 15 | 72 | 403 | 0 | 25 | 5.6 | 25.2 | 12 |
| 98 | Steve McNair | 1999 | 26 | TEN | QB | 11 | 11 | 72 | 337 | 8 | 38 | 4.7 | 30.6 | 3 |
| 99 | Sid Blanks | 1966 | 26 | HOU | hb | 14 | 0 | 71 | 235 | 0 | 30 | 3.3 | 16.8 | 2 |
| 100 | Marion Butts | 1995 | 29 | HOU | 12 | 2 | 71 | 185 | 4 | 9 | 2.6 | 15.4 | 0 | |
| 101 | Willie Rodgers | 1972 | 23 | HOU | RET | 14 | 0 | 71 | 204 | 2 | 14 | 2.9 | 14.6 | 5 |
| 102 | John Henry Johnson | 1966 | 37 | HOU | 14 | 0 | 70 | 226 | 3 | 28 | 3.2 | 16.1 | 0 | |
| 103 | Warren Moon | 1989* | 33 | HOU | QB | 16 | 16 | 70 | 268 | 4 | 19 | 3.8 | 16.8 | 11 |
| 104 | Rodney Thomas | 1997 | 24 | TEN | 16 | 1 | 67 | 310 | 3 | 25 | 4.6 | 19.4 | 1 | |
| 105 | Sid Blanks | 1967 | 27 | HOU | 13 | 0 | 66 | 206 | 1 | 16 | 3.1 | 15.8 | 2 | |
| 106 | Allen Pinkett | 1990 | 26 | HOU | 15 | 0 | 66 | 268 | 0 | 19 | 4.1 | 17.9 | 0 | |
| 107 | Tim Wilson | 1980 | 26 | HOU | FB | 16 | 16 | 66 | 257 | 1 | 15 | 3.9 | 16.1 | 2 |
| 108 | Larry Moriarty | 1983 | 25 | HOU | FB | 16 | 7 | 65 | 321 | 3 | 80 | 4.9 | 20.1 | 1 |
| 109 | Sid Blanks | 1968 | 28 | HOU | HB | 14 | 0 | 63 | 169 | 0 | 10 | 2.7 | 12.1 | 3 |
| 110 | Robert Holcombe | 2003 | 28 | TEN | 15 | 0 | 63 | 201 | 1 | 21 | 3.2 | 13.4 | 2 | |
| 111 | LenDale White | 2008 | 24 | TEN | 5 | 63 | 165 | 5 | 17 | 2.6 | 33.0 | 0 | ||
| 112 | Ronnie Coleman | 1978 | 27 | HOU | RET | 15 | 0 | 61 | 188 | 1 | 16 | 3.1 | 12.5 | 4 |
| 113 | Rodney Thomas | 2000 | 27 | TEN | 16 | 0 | 61 | 175 | 0 | 20 | 2.9 | 10.9 | 1 | |
| 114 | LenDale White | 2006 | 22 | TEN | 13 | 0 | 61 | 244 | 0 | 26 | 4.0 | 18.8 | 0 | |
| 115 | Stan Edwards | 1984 | 24 | HOU | 14 | 1 | 60 | 267 | 1 | 20 | 4.5 | 19.1 | 2 | |
| 116 | Andrew Jackson | 1987 | 23 | HOU | 7 | 3 | 60 | 232 | 1 | 16 | 3.9 | 33.1 | 0 | |
| 117 | Dave Smith | 1961 | 24 | HOU | 14 | 0 | 60 | 258 | 2 | 21 | 4.3 | 18.4 | 3 | |
| 118 | George Amundson | 1974 | 23 | HOU | 14 | 0 | 59 | 138 | 4 | 11 | 2.3 | 9.9 | 1 | |
| 119 | Woody Campbell | 1970 | 26 | HOU | rb | 6 | 0 | 59 | 189 | 1 | 28 | 3.2 | 31.5 | 0 |
| Rushing | ||||||||||||||
| Rk | Year | Age | Tm | Pos | G | GS | Att | Yds | TD | Lng | Fmb | |||
| 120 | Warren Moon | 1984 | 28 | HOU | QB | 16 | 16 | 58 | 211 | 1 | 31 | 3.6 | 13.2 | 17 |
| 121 | Roy Hopkins | 1970 | 25 | HOU | 12 | 0 | 57 | 207 | 3 | 12 | 3.6 | 17.3 | 0 | |
| 122 | Chris Brown | 2003 | 22 | TEN | 11 | 0 | 56 | 221 | 0 | 28 | 3.9 | 20.1 | 1 | |
| 123 | Hoyle Granger | 1966 | 22 | HOU | 11 | 0 | 56 | 388 | 1 | 69 | 6.9 | 35.3 | 0 | |
| 124 | Skip Hicks | 2001 | 27 | TEN | 9 | 0 | 56 | 341 | 1 | 51 | 6.1 | 37.9 | 0 | |
| 125 | Dave Smith | 1962 | 25 | HOU | 14 | 0 | 56 | 249 | 1 | 41 | 4.4 | 17.8 | 0 | |
| 126 | Donnie Craft | 1983 | 24 | HOU | 15 | 2 | 55 | 147 | 0 | 8 | 2.7 | 9.8 | 0 | |
| 127 | Warren Moon | 1990* | 34 | HOU | QB | 15 | 15 | 55 | 215 | 2 | 17 | 3.9 | 14.3 | 18 |
| 128 | Larry Moriarty | 1986 | 28 | HOU | 5 | 4 | 55 | 137 | 1 | 9 | 2.5 | 27.4 | 1 | |
| 129 | Charley Tolar | 1960 | 23 | HOU | 14 | 0 | 54 | 179 | 3 | 40 | 3.3 | 12.8 | 6 | |
| 130 | Ronnie Coleman | 1974 | 23 | HOU | 13 | 0 | 52 | 193 | 1 | 37 | 3.7 | 14.8 | 1 | |
| 131 | Ray Wallace | 1986 | 23 | HOU | 8 | 4 | 52 | 218 | 3 | 19 | 4.2 | 27.3 | 1 | |
| 132 | Hoyle Granger | 1970 | 26 | HOU | fb | 5 | 0 | 51 | 169 | 1 | 15 | 3.3 | 33.8 | 2 |
| 133 | Dave Smith | 1963 | 26 | HOU | 14 | 0 | 50 | 202 | 3 | 16 | 4.0 | 14.4 | 1 | |
| 134 | Rodney Thomas | 1996 | 23 | HOU | 16 | 0 | 49 | 151 | 1 | 24 | 3.1 | 9.4 | 0 | |
| 135 | Warren Moon | 1993* | 37 | HOU | QB | 15 | 14 | 48 | 145 | 1 | 35 | 3.0 | 9.7 | 13 |
| 136 | Robert Holcombe | 2002 | 27 | TEN | 8 | 0 | 47 | 242 | 0 | 39 | 5.1 | 30.3 | 1 | |
| 137 | Jack Spikes | 1965 | 28 | HOU | 14 | 0 | 47 | 173 | 3 | 20 | 3.7 | 12.4 | 3 | |
| 138 | Charley Tolar | 1966 | 29 | HOU | FB | 14 | 0 | 46 | 105 | 0 | 17 | 2.3 | 7.5 | 3 |
| 139 | Robert Holmes | 1972 | 27 | HOU | 6 | 0 | 43 | 172 | 0 | 18 | 4.0 | 28.7 | 0 | |
| 140 | Rodney Thomas | 1999 | 26 | TEN | 16 | 0 | 43 | 164 | 1 | 22 | 3.8 | 10.3 | 0 | |
| 141 | Joe Dawkins | 1971 | 23 | HOU | 6 | 0 | 42 | 135 | 2 | 21 | 3.2 | 22.5 | 0 | |
| 142 | Hoyle Granger | 1972 | 28 | HOU | fb | 13 | 0 | 42 | 175 | 0 | 14 | 4.2 | 13.5 | 2 |
| 143 | Don Hardeman | 1977 | 25 | HOU | 12 | 0 | 42 | 162 | 2 | 18 | 3.9 | 13.5 | 0 | |
| 144 | Warren Moon | 1986 | 30 | HOU | QB | 15 | 15 | 42 | 157 | 2 | 19 | 3.7 | 10.5 | 11 |
| 145 | Chris Brown | 2006 | 25 | TEN | 5 | 3 | 41 | 156 | 0 | 21 | 3.8 | 31.2 | 1 | |
| 146 | Ode Burrell | 1969 | 30 | HOU | 13 | 0 | 41 | 147 | 0 | 19 | 3.6 | 11.3 | 2 | |
| 147 | Warren Moon | 1985 | 29 | HOU | QB | 14 | 14 | 39 | 130 | 0 | 17 | 3.3 | 9.3 | 12 |
| 148 | Steve McNair | 2003* | 30 | TEN | QB | 14 | 14 | 38 | 138 | 4 | 23 | 3.6 | 9.9 | 12 |
| 149 | Dan Pastorini | 1972 | 23 | HOU | QB | 14 | 12 | 38 | 205 | 2 | 17 | 5.4 | 14.6 | 6 |
| Rushing | ||||||||||||||
| Rk | Year | Age | Tm | Pos | G | GS | Att | Yds | TD | Lng | Fmb | |||
| 150 | Don Trull | 1966 | 25 | HOU | qb | 14 | 5 | 38 | 139 | 7 | 23 | 3.7 | 9.9 | 3 |
| 151 | Ward Walsh | 1971 | 24 | HOU | 13 | 0 | 38 | 129 | 0 | 19 | 3.4 | 9.9 | 2 | |
| 152 | Doug Cline | 1960 | 22 | HOU | LLB | 14 | 0 | 37 | 105 | 2 | 19 | 2.8 | 7.5 | 2 |
| 153 | Bobby Jackson | 1965 | 25 | HOU | 10 | 0 | 37 | 85 | 2 | 7 | 2.3 | 8.5 | 0 | |
| 154 | Herman Hunter | 1987 | 26 | HOU | 3 | 0 | 34 | 144 | 0 | 21 | 4.2 | 48.0 | 1 | |
| 155 | Warren Moon | 1987 | 31 | HOU | QB | 12 | 12 | 34 | 112 | 3 | 20 | 3.3 | 9.3 | 8 |
| 156 | Paul Robinson | 1973 | 29 | HOU | 11 | 0 | 34 | 151 | 2 | 22 | 4.4 | 13.7 | 0 | |
| 157 | Warren Moon | 1991* | 35 | HOU | QB | 16 | 16 | 33 | 68 | 2 | 12 | 2.1 | 4.3 | 11 |
| 158 | Warren Moon | 1988* | 32 | HOU | QB | 11 | 11 | 33 | 88 | 5 | 14 | 2.7 | 8.0 | 8 |
| 159 | Jarrett Payton | 2005 | 25 | TEN | 13 | 0 | 33 | 105 | 2 | 15 | 3.2 | 8.1 | 0 | |
| 160 | Pete Beathard | 1967 | 25 | HOU | QB | 10 | 9 | 32 | 133 | 1 | 23 | 4.2 | 13.3 | 3 |
| 161 | Don Hardeman | 1976 | 24 | HOU | 13 | 0 | 32 | 114 | 1 | 21 | 3.6 | 8.8 | 0 | |
| 162 | Steve McNair | 2005* | 32 | TEN | QB | 14 | 14 | 32 | 139 | 1 | 19 | 4.3 | 9.9 | 7 |
| 163 | Adger Armstrong | 1981 | 24 | HOU | 16 | 2 | 31 | 146 | 0 | 18 | 4.7 | 9.1 | 2 | |
| 164 | Joe Dawkins | 1976 | 28 | HOU | 14 | 0 | 31 | 61 | 1 | 7 | 2.0 | 4.4 | 0 | |
| 165 | Chris J. Henry | 2007 | 22 | TEN | 7 | 0 | 31 | 119 | 2 | 24 | 3.8 | 17.0 | 0 | |
| 166 | Roy Hopkins | 1968 | 23 | HOU | 13 | 0 | 31 | 104 | 0 | 18 | 3.4 | 8.0 | 0 | |
| 167 | Steve McNair | 1996 | ||||||||||||