| Offensive Starters | | | | | |
|---|
| QB | Josh Allen* | 28 | 6 | 17 | 307 for 483, 3,731 yards, 28 td, 6 int, & 102 rushes for 531 yards and 12 td | |
|---|
| RB | James Cook* | 25 | 2 | 16 | 207 rushes for 1,009 yards, 16 td, & 32 catches for 258 yards and 2 td | |
|---|
| WR | Keon Coleman | 21 | Rook | 12 | 29 catches for 556 yards, 4 td, & 1 rush for 9 yards and 0 td | |
|---|
| WR | Mack Hollins | 31 | 7 | 13 | 31 catches for 378 yards, 5 td | |
|---|
| WR | Khalil Shakir | 24 | 2 | 9 | 76 catches for 821 yards, 4 td, & 2 rushes for 4 yards and 0 td | |
|---|
| TE | Dawson Knox | 28 | 5 | 13 | 22 catches for 311 yards, 1 td | |
|---|
| LT | Dion Dawkins* | 30 | 7 | 16 | | |
|---|
| LG | David Edwards | 27 | 5 | 16 | | |
|---|
| C | Connor McGovern* | 27 | 4 | 16 | | |
|---|
| RG | O'Cyrus Torrence | 24 | 1 | 16 | 2 fumbles recovered | |
|---|
| RT | Spencer Brown | 26 | 3 | 15 | | |
|---|
| Defensive Starters | | | | | |
|---|
| LDE | A.J. Epenesa | 26 | 4 | 13 | 6.0 sacks, 0 interceptions, 0 fumbles recovered | |
|---|
| LDT | Ed Oliver | 27 | 5 | 14 | 3.0 sacks, 0 interceptions, 0 fumbles recovered | |
|---|
| RDT | DaQuan Jones | 33 | 10 | 16 | 2.5 sacks, 0 interceptions, 0 fumbles recovered | |
|---|
| RDE | Gregory Rousseau | 24 | 3 | 16 | 8.0 sacks, 0 interceptions, 1 fumble recovered | |
|---|
| MLB | Terrel Bernard | 25 | 2 | 13 | 1.0 sacks, 2 interceptions, 1 fumble recovered | |
|---|
| RLB | Dorian Williams | 23 | 1 | 11 | 0.0 sacks, 0 interceptions, 3 fumbles recovered | |
|---|
| LCB | Rasul Douglas | 29 | 7 | 15 | | |
|---|
| RCB | Christian Benford | 24 | 2 | 15 | 1.0 sacks, 2 interceptions, 1 fumble recovered | |
|---|
| SS | Damar Hamlin | 26 | 3 | 14 | 0.0 sacks, 2 interceptions, 1 fumble recovered | |
|---|
| FS | Taylor Rapp | 27 | 5 | 14 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | |
|---|
| DB | Taron Johnson | 28 | 6 | 12 | | |
|---|
Roster