| Offensive Starters | | | | | |
| QB | Joe Burrow* | 29 | 5 | 8 | 173 for 259, 1,809 yards, 17 td, 5 int, & 14 rushes for 41 yards and 0 td | |
| RB | Chase Brown | 25 | 2 | 17 | 232 rushes for 1,019 yards, 6 td, & 69 catches for 437 yards and 5 td | |
| WR | Ja'Marr Chase*+ | 25 | 4 | 16 | 125 catches for 1,412 yards, 8 td, & 3 rushes for 14 yards and 0 td | |
| WR | Tee Higgins* | 26 | 5 | 14 | 59 catches for 846 yards, 11 td | |
| WR | Andrei Iosivas | 26 | 2 | 9 | 33 catches for 435 yards, 2 td, & 3 rushes for 14 yards and 0 td | |
| TE | Drew Sample | 29 | 6 | 12 | 15 catches for 106 yards, 1 td, & 1 rush for 3 yards and 0 td | |
| LT | Orlando Brown Jr. | 29 | 7 | 17 | 1 fumble recovered | |
| LG | Dylan Fairchild | 22 | Rook | 15 | 1 fumble recovered | |
| C | Ted Karras | 32 | 9 | 17 | | |
| RG | Dalton Risner | 30 | 6 | 11 | | |
| RT | Amarius Mims | 23 | 1 | 17 | | |
| Defensive Starters | | | | | |
| DE | Myles Murphy | 23 | 2 | 10 | 5.5 sacks, 0 interceptions, 1 fumble recovered | |
| DE | Joseph Ossai | 25 | 3 | 9 | 5.0 sacks, 0 interceptions, 0 fumbles recovered | |
| DT | B.J. Hill | 30 | 7 | 17 | 4.0 sacks, 0 interceptions, 0 fumbles recovered | |
| DT | Tedarrell Slaton | 28 | 4 | 17 | 3.0 sacks, 0 interceptions, 0 fumbles recovered | |
| LB | Oren Burks | 30 | 7 | 9 | 0.0 sacks, 0 interceptions, 1 fumble recovered | |
| LB | Barrett Carter | 23 | Rook | 12 | 0.0 sacks, 1 interception, 0 fumbles recovered | |
| LB | Demetrius Knight | 25 | Rook | 14 | 3.0 sacks, 2 interceptions, 0 fumbles recovered | |
| CB | Daxton Hill | 25 | 3 | 17 | 0.0 sacks, 1 interception, 0 fumbles recovered | |
| CB | DJ Turner | 25 | 2 | 16 | 0.0 sacks, 2 interceptions, 1 fumble recovered | |
| S | Jordan Battle | 25 | 2 | 17 | 0.0 sacks, 4 interceptions, 0 fumbles recovered | |
| S | Geno Stone | 26 | 5 | 17 | 2.0 sacks, 2 interceptions, 0 fumbles recovered | |
Roster