| Offensive Starters | | | | | |
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| QB | Kyler Murray | 22 | Rook | 16 | 349 for 542, 3,722 yards, 20 td, 12 int, & 93 rushes for 544 yards and 4 td | |
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| RB | Kenyan Drake | 25 | 3 | 8 | 123 rushes for 643 yards, 8 td, & 28 catches for 171 yards and 0 td | |
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| WR | Larry Fitzgerald | 36 | 15 | 16 | 75 catches for 804 yards, 4 td | |
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| WR | Christian Kirk | 23 | 1 | 13 | 68 catches for 709 yards, 3 td, & 10 rushes for 93 yards and 0 td | |
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| TE | Charles Clay | 30 | 8 | 10 | 18 catches for 237 yards, 1 td | |
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| TE | Maxx Williams | 25 | 4 | 10 | 15 catches for 202 yards, 1 td | |
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| LT | D.J. Humphries | 26 | 3 | 16 | | |
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| LG | Justin Pugh | 29 | 6 | 16 | | |
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| C | A.Q. Shipley | 33 | 7 | 16 | | |
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| RG | J.R. Sweezy | 30 | 7 | 16 | | |
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| RT | Justin Murray | 26 | 1 | 12 | | |
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| Defensive Starters | | | | | |
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| LDE | Jonathan Bullard | 26 | 3 | 6 | 1.5 sacks, 0 interceptions, 0 fumbles recovered | |
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| NT | Corey Peters | 31 | 9 | 16 | 2.5 sacks, 0 interceptions, 0 fumbles recovered | |
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| RDE | Rodney Gunter | 27 | 4 | 13 | 3.0 sacks, 0 interceptions, 0 fumbles recovered | |
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| LOLB | Chandler Jones*+ | 29 | 7 | 16 | 19.0 sacks, 0 interceptions, 3 fumbles recovered | |
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| LILB | Joe Walker | 27 | 2 | 11 | | |
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| RILB | Jordan Hicks | 27 | 4 | 16 | 1.5 sacks, 3 interceptions, 1 fumble recovered | |
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| ROLB | Terrell Suggs | 37 | 16 | 13 | 5.5 sacks, 0 interceptions, 1 fumble recovered | |
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| LCB | Byron Murphy | 21 | Rook | 16 | 0.0 sacks, 1 interception, 0 fumbles recovered | |
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| RCB | Patrick Peterson | 29 | 8 | 10 | 1.0 sacks, 2 interceptions, 0 fumbles recovered | |
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| SS | Jalen Thompson | 21 | Rook | 9 | 0.0 sacks, 1 interception, 1 fumble recovered | |
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| FS | Budda Baker* | 23 | 2 | 16 | 0.5 sacks, 0 interceptions, 1 fumble recovered | |
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Roster