| Offensive Starters | | | | | |
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| QB | Drew Brees*+ | 27 | 5 | 16 | 356 for 554, 4,418 yards, 26 td, 11 int, & 42 rushes for 32 yards and 0 td | |
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| RB | Deuce McAllister | 28 | 5 | 13 | 244 rushes for 1,057 yards, 10 td, & 30 catches for 198 yards and 0 td | |
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| FB | Mike Karney | 25 | 2 | 7 | 11 rushes for 33 yards, 1 td, & 15 catches for 96 yards and 2 td | |
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| WR | Marques Colston | 23 | Rook | 12 | 70 catches for 1,038 yards, 8 td | |
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| WR | Joe Horn | 34 | 10 | 9 | 37 catches for 679 yards, 4 td | |
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| TE | Mark Campbell | 31 | 7 | 10 | 18 catches for 164 yards, 0 td | |
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| LT | Jammal Brown*+ | 25 | 1 | 15 | 1 fumble recovered | |
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| LG | Jamar Nesbit | 30 | 7 | 16 | | |
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| C | Jeff Faine | 25 | 3 | 16 | 1 fumble recovered | |
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| RG | Jahri Evans | 23 | Rook | 16 | 2 fumbles recovered | |
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| RT | Jon Stinchcomb | 27 | 3 | 16 | 1 fumble recovered | |
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| Defensive Starters | | | | | |
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| LDE | Charles Grant | 28 | 4 | 16 | 6.0 sacks, 0 interceptions, 2 fumbles recovered | |
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| LDT | Brian Young | 29 | 6 | 16 | 5.5 sacks, 0 interceptions, 1 fumble recovered | |
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| RDT | Hollis Thomas | 32 | 10 | 12 | 3.5 sacks, 0 interceptions, 1 fumble recovered | |
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| RDE | Will Smith* | 25 | 2 | 14 | 10.5 sacks, 0 interceptions, 1 fumble recovered | |
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| LLB | Scott Fujita | 27 | 4 | 16 | 3.5 sacks, 2 interceptions, 0 fumbles recovered | |
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| MLB | Mark Simoneau | 29 | 6 | 13 | 1.0 sacks, 1 interception, 0 fumbles recovered | |
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| RLB | Scott Shanle | 27 | 3 | 15 | 4.0 sacks, 0 interceptions, 0 fumbles recovered | |
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| LCB | Mike McKenzie | 30 | 7 | 16 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | |
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| RCB | Fred Thomas | 33 | 10 | 13 | 0.0 sacks, 1 interception, 0 fumbles recovered | |
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| SS | Omar Stoutmire | 32 | 9 | 9 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | |
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| FS | Josh Bullocks | 23 | 1 | 16 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | |
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Roster