| Offensive Starters | | | | | |
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| QB | Drew Brees* | 40 | 18 | 11 | 281 for 378, 2,979 yards, 27 td, 4 int, & 9 rushes for -4 yards and 1 td | San Diego Chargers / 2nd / 32nd pick / 2001 |
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| RB | Alvin Kamara* | 24 | 2 | 9 | 171 rushes for 797 yards, 5 td, & 81 catches for 533 yards and 1 td | New Orleans Saints / 3rd / 67th pick / 2017 |
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| RB | Latavius Murray | 29 | 6 | 8 | 146 rushes for 637 yards, 5 td, & 34 catches for 235 yards and 1 td | Oakland Raiders / 6th / 181st pick / 2013 |
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| WR | Ted Ginn | 34 | 12 | 9 | 30 catches for 421 yards, 2 td, & 3 rushes for 18 yards and 0 td | Miami Dolphins / 1st / 9th pick / 2007 |
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| WR | Michael Thomas*+ | 26 | 3 | 15 | 149 catches for 1,725 yards, 9 td, & 1 rush for -9 yards and 0 td | New Orleans Saints / 2nd / 47th pick / 2016 |
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| TE | Josh Hill | 29 | 6 | 11 | 25 catches for 226 yards, 3 td | |
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| T | Terron Armstead* | 28 | 6 | 15 | | New Orleans Saints / 3rd / 75th pick / 2013 |
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| T | Ryan Ramczyk+ | 25 | 2 | 16 | | New Orleans Saints / 1st / 32nd pick / 2017 |
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| G | Andrus Peat* | 26 | 4 | 10 | | New Orleans Saints / 1st / 13th pick / 2015 |
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| G | Larry Warford* | 28 | 6 | 15 | | Detroit Lions / 3rd / 65th pick / 2013 |
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| C | Erik McCoy | 22 | Rook | 16 | | New Orleans Saints / 2nd / 48th pick / 2019 |
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| Defensive Starters | | | | | |
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| DE | Marcus Davenport | 23 | 1 | 13 | | New Orleans Saints / 1st / 14th pick / 2018 |
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| DE | Cameron Jordan* | 30 | 8 | 16 | | New Orleans Saints / 1st / 24th pick / 2011 |
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| DT | Malcom Brown | 25 | 4 | 16 | | New England Patriots / 1st / 32nd pick / 2015 |
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| DT | David Onyemata | 27 | 3 | 15 | | New Orleans Saints / 4th / 120th pick / 2016 |
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| LB | Demario Davis+ | 30 | 7 | 16 | | New York Jets / 3rd / 77th pick / 2012 |
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| LB | A.J. Klein | 28 | 6 | 15 | | Carolina Panthers / 5th / 148th pick / 2013 |
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| CB | Eli Apple | 24 | 3 | 15 | | New York Giants / 1st / 10th pick / 2016 |
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| CB | Marshon Lattimore* | 23 | 2 | 14 | 0.0 sacks, 1 interception, 0 fumbles recovered | New Orleans Saints / 1st / 11th pick / 2017 |
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| S | Vonn Bell | 25 | 3 | 13 | 1.5 sacks, 1 interception, 5 fumbles recovered | New Orleans Saints / 2nd / 61st pick / 2016 |
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| S | Marcus Williams | 23 | 2 | 15 | 0.0 sacks, 4 interceptions, 0 fumbles recovered | New Orleans Saints / 2nd / 42nd pick / 2017 |
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| Special Teams Starters | | | | | |
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| K | Wil Lutz* | 25 | 3 | 0 | 32 of 36 field goals & 48 of 49 extra points | |
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| P | Thomas Morstead | 33 | 10 | 0 | 60 punts for a 46.2 average, 0 blocked | New Orleans Saints / 5th / 164th pick / 2009 |
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Roster