| Offensive Starters | | | | | |
| QB | Carson Palmer | 33 | 8 | 15 | 345 for 565, 4,018 yards, 22 td, 14 int, & 18 rushes for 36 yards and 1 td | |
| RB | Darren McFadden | 25 | 4 | 12 | 216 rushes for 707 yards, 2 td, & 42 catches for 258 yards and 1 td | |
| RB | Marcel Reece* | 27 | 3 | 14 | 59 rushes for 271 yards, 0 td, & 52 catches for 496 yards and 1 td | |
| WR | Darrius Heyward-Bey | 25 | 3 | 14 | 41 catches for 606 yards, 5 td, & 2 rushes for 16 yards and 0 td | |
| WR | Denarius Moore | 24 | 1 | 15 | 51 catches for 741 yards, 7 td, & 1 rush for -5 yards and 0 td | |
| TE | Brandon Myers | 27 | 3 | 16 | 79 catches for 806 yards, 4 td | |
| LT | Jared Veldheer | 25 | 2 | 16 | | |
| LG | Cooper Carlisle | 35 | 12 | 16 | | |
| C | Stefen Wisniewski | 23 | 1 | 15 | | |
| RG | Mike Brisiel | 29 | 5 | 15 | | |
| RT | Khalif Barnes | 30 | 7 | 9 | | |
| Defensive Starters | | | | | |
| LDE | Lamarr Houston | 25 | 2 | 16 | 4.5 sacks, 0 interceptions, 1 fumble recovered | |
| LDT | Richard Seymour | 33 | 11 | 8 | 3.0 sacks, 0 interceptions, 1 fumble recovered | |
| RDT | Tommy Kelly | 32 | 8 | 16 | 1.5 sacks, 0 interceptions, 1 fumble recovered | |
| RDE | Matt Shaughnessy | 26 | 3 | 16 | 3.5 sacks, 0 interceptions, 0 fumbles recovered | |
| LLB | Philip Wheeler | 28 | 4 | 16 | 3.0 sacks, 0 interceptions, 1 fumble recovered | |
| MLB | Rolando McClain | 23 | 2 | 9 | 1.0 sacks, 0 interceptions, 0 fumbles recovered | |
| RLB | Miles Burris | 24 | Rook | 15 | 1.5 sacks, 1 interception, 0 fumbles recovered | |
| LCB | Michael Huff | 29 | 6 | 16 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | |
| RCB | Pat Lee | 28 | 4 | 7 | 0.0 sacks, 1 interception, 0 fumbles recovered | |
| SS | Tyvon Branch | 26 | 4 | 14 | 0.0 sacks, 1 interception, 0 fumbles recovered | |
| FS | Matt Giordano | 30 | 7 | 13 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | |
Roster