Starters
- *ProBowl, +1st-tm All-Pro
| Pos | Player | Age | Yrs | GS | Summary of Player Stats | Drafted (tm/rnd/yr) |
|---|---|---|---|---|---|---|
| Offensive Starters | ||||||
| QB | Marc Bulger | 31 | 6 | 15 | 251 for 440, 2,720 yards, 11 td, 13 int, & 14 rushes for 41 yards and 0 td | |
| RB | Steven Jackson | 25 | 4 | 11 | 253 rushes for 1,042 yards, 7 td, & 40 catches for 379 yards and 1 td | |
| WR | Donnie Avery | 24 | Rook | 12 | 53 catches for 674 yards, 3 td, & 10 rushes for 69 yards and 1 td | |
| WR | Torry Holt | 32 | 9 | 14 | 64 catches for 796 yards, 3 td | |
| TE | Anthony Becht | 31 | 8 | 11 | 6 catches for 39 yards, 0 td | |
| TE | Joe Klopfenstein | 25 | 2 | 10 | 11 catches for 123 yards, 0 td | |
| LT | Orlando Pace | 33 | 11 | 14 | ||
| LG | Jacob Bell | 27 | 4 | 13 | ||
| C | Nick Leckey | 26 | 4 | 10 | ||
| RG | Richie Incognito | 25 | 2 | 15 | ||
| RT | Alex Barron | 26 | 3 | 15 | ||
| Defensive Starters | ||||||
| LDE | Victor Adeyanju | 25 | 2 | 9 | 2.0 sacks, 0 interceptions, 0 fumbles recovered | |
| LDT | La'Roi Glover | 34 | 12 | 9 | 0.5 sacks, 0 interceptions, 0 fumbles recovered | |
| RDT | Clifton Ryan | 24 | 1 | 12 | ||
| RDE | Chris Long | 23 | Rook | 16 | 4.0 sacks, 0 interceptions, 1 fumble recovered | |
| LLB | Quinton Culberson | 23 | 1 | 10 | 0.0 sacks, 0 interceptions, 1 fumble recovered | |
| MLB | Will Witherspoon | 28 | 6 | 12 | 1.0 sacks, 1 interception, 1 fumble recovered | |
| RLB | Pisa Tinoisamoa | 27 | 5 | 16 | 3.0 sacks, 0 interceptions, 0 fumbles recovered | |
| LCB | Ron Bartell | 26 | 3 | 15 | 1.0 sacks, 3 interceptions, 1 fumble recovered | |
| RCB | Fakhir Brown | 31 | 9 | 11 | 1.0 sacks, 1 interception, 1 fumble recovered | |
| SS | Corey Chavous | 32 | 10 | 13 | 0.0 sacks, 0 interceptions, 1 fumble recovered | |
| FS | O.J. Atogwe | 27 | 3 | 16 | 0.0 sacks, 5 interceptions, 3 fumbles recovered |
Roster