| Offensive Starters | | | | | |
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| QB | Jared Goff | 26 | 4 | 15 | 370 for 552, 3,952 yards, 20 td, 13 int, & 51 rushes for 99 yards and 4 td | Los Angeles Rams / 1st / 1st pick / 2016 |
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| RB | Darrell Henderson | 23 | 1 | 11 | 138 rushes for 624 yards, 5 td, & 16 catches for 159 yards and 1 td | Los Angeles Rams / 3rd / 70th pick / 2019 |
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| WR | Cooper Kupp | 27 | 3 | 12 | 92 catches for 974 yards, 3 td, & 4 rushes for 33 yards and 0 td | Los Angeles Rams / 3rd / 69th pick / 2017 |
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| WR | Josh Reynolds | 25 | 3 | 13 | 52 catches for 618 yards, 2 td, & 1 rush for 5 yards and 0 td | Los Angeles Rams / 4th / 117th pick / 2017 |
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| WR | Robert Woods | 28 | 7 | 16 | 90 catches for 936 yards, 6 td, & 24 rushes for 155 yards and 2 td | Buffalo Bills / 2nd / 41st pick / 2013 |
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| TE | Tyler Higbee | 27 | 4 | 15 | 44 catches for 521 yards, 5 td, & 1 rush for 1 yards and 0 td | Los Angeles Rams / 4th / 110th pick / 2016 |
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| T | Rob Havenstein | 28 | 5 | 16 | | St. Louis Rams / 2nd / 57th pick / 2015 |
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| G | Austin Corbett | 25 | 2 | 16 | | Cleveland Browns / 2nd / 33rd pick / 2018 |
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| G | David Edwards | 23 | 1 | 14 | | Los Angeles Rams / 5th / 169th pick / 2019 |
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| C | Austin Blythe | 28 | 4 | 16 | | Indianapolis Colts / 7th / 248th pick / 2016 |
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| Defensive Starters | | | | | |
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| DE | Michael Brockers | 30 | 8 | 15 | | St. Louis Rams / 1st / 14th pick / 2012 |
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| DT | Aaron Donald*+ | 29 | 6 | 16 | | St. Louis Rams / 1st / 13th pick / 2014 |
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| NT | Sebastian Joseph | 25 | 2 | 16 | 1.0 sacks, 0 interceptions, 0 fumbles recovered | Los Angeles Rams / 6th / 195th pick / 2018 |
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| OLB | Samson Ebukam | 25 | 3 | 14 | | Los Angeles Rams / 4th / 125th pick / 2017 |
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| OLB | Leonard Floyd | 28 | 4 | 16 | | Chicago Bears / 1st / 9th pick / 2016 |
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| CB | Troy Hill | 29 | 5 | 16 | 0.0 sacks, 3 interceptions, 2 fumbles recovered | |
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| CB | Jalen Ramsey*+ | 26 | 4 | 15 | 0.0 sacks, 1 interception, 0 fumbles recovered | Jacksonville Jaguars / 1st / 5th pick / 2016 |
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| CB | Darious Williams | 27 | 2 | 10 | 0.0 sacks, 4 interceptions, 0 fumbles recovered | |
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| FS | Jordan Fuller | 22 | Rook | 12 | 0.0 sacks, 3 interceptions, 0 fumbles recovered | Los Angeles Rams / 6th / 199th pick / 2020 |
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| FS | John Johnson | 25 | 3 | 16 | 0.0 sacks, 1 interception, 0 fumbles recovered | Los Angeles Rams / 3rd / 91st pick / 2017 |
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Roster