| Offensive Starters | | | | | |
| QB | Philip Rivers | 38 | 15 | 16 | 390 for 591, 4,615 yards, 23 td, 20 int, & 12 rushes for 29 yards and 0 td | |
| RB | Melvin Gordon | 26 | 4 | 11 | 162 rushes for 612 yards, 8 td, & 42 catches for 296 yards and 1 td | |
| WR | Keenan Allen* | 27 | 6 | 16 | 104 catches for 1,199 yards, 6 td, & 3 rushes for 16 yards and 0 td | |
| WR | Andre Patton | 25 | Rook | 5 | 6 catches for 56 yards, 0 td | |
| WR | Mike Williams | 25 | 2 | 15 | 49 catches for 1,001 yards, 2 td, & 1 rush for 2 yards and 0 td | |
| TE | Hunter Henry | 25 | 3 | 12 | 55 catches for 652 yards, 5 td | |
| LT | Trenton Scott | 25 | 1 | 9 | 1 fumble recovered | |
| LG | Dan Feeney | 25 | 2 | 16 | 1 fumble recovered | |
| C | Scott Quessenberry | 24 | 1 | 9 | | |
| RG | Michael Schofield | 29 | 4 | 16 | 1 fumble recovered | |
| RT | Sam Tevi | 25 | 2 | 14 | | |
| Defensive Starters | | | | | |
| LDE | Joey Bosa* | 24 | 3 | 16 | 11.5 sacks, 0 interceptions, 0 fumbles recovered | |
| LDT | Justin Jones | 23 | 1 | 12 | | |
| RDT | Brandon Mebane | 34 | 12 | 13 | 1.0 sacks, 0 interceptions, 0 fumbles recovered | |
| RDE | Melvin Ingram* | 30 | 7 | 13 | 7.0 sacks, 1 interception, 1 fumble recovered | |
| LLB | Thomas Davis | 36 | 14 | 16 | 1.0 sacks, 0 interceptions, 0 fumbles recovered | |
| MLB | Denzel Perryman | 27 | 4 | 10 | 0.0 sacks, 1 interception, 0 fumbles recovered | |
| LCB | Michael Davis | 24 | 2 | 12 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | |
| RCB | Casey Hayward | 30 | 7 | 16 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | |
| SS | Rayshawn Jenkins | 25 | 2 | 16 | 0.0 sacks, 3 interceptions, 0 fumbles recovered | |
| FS | Roderic Teamer | 22 | Rook | 6 | 1.0 sacks, 1 interception, 0 fumbles recovered | |
| DB | Desmond King | 25 | 2 | 8 | | |
Roster