| Offensive Starters | | | | | |
| QB | Mark Brunell | 36 | 12 | 9 | 162 for 260, 1,789 yards, 8 td, 4 int, & 13 rushes for 34 yards and 0 td | |
| RB | Ladell Betts | 27 | 4 | 9 | 245 rushes for 1,154 yards, 4 td, & 53 catches for 445 yards and 1 td | |
| WR | Brandon Lloyd | 25 | 3 | 12 | 23 catches for 365 yards, 0 td | |
| WR | Santana Moss | 27 | 5 | 14 | 55 catches for 790 yards, 6 td, & 7 rushes for 82 yards and 0 td | |
| WR | Antwaan Randle El | 27 | 4 | 16 | 32 catches for 351 yards, 3 td, & 19 rushes for 118 yards and 0 td | |
| TE | Chris Cooley | 24 | 2 | 16 | 57 catches for 734 yards, 6 td | |
| LT | Chris Samuels* | 29 | 6 | 16 | | |
| LG | Derrick Dockery | 26 | 3 | 16 | | |
| C | Casey Rabach | 29 | 4 | 16 | | |
| RG | Randy Thomas | 30 | 7 | 16 | | |
| RT | Jon Jansen | 30 | 7 | 15 | | |
| Defensive Starters | | | | | |
| LDE | Phillip Daniels | 33 | 10 | 15 | 3.0 sacks, 1 interception, 0 fumbles recovered | |
| LDT | Cornelius Griffin | 30 | 6 | 14 | 1.0 sacks, 0 interceptions, 0 fumbles recovered | |
| RDT | Kedric Golston | 23 | Rook | 13 | 0.5 sacks, 0 interceptions, 1 fumble recovered | |
| RDE | Andre Carter | 27 | 5 | 16 | 6.0 sacks, 0 interceptions, 0 fumbles recovered | |
| LLB | Marcus Washington | 29 | 6 | 14 | 2.5 sacks, 0 interceptions, 2 fumbles recovered | |
| MLB | Lemar Marshall | 30 | 4 | 15 | 1.5 sacks, 0 interceptions, 1 fumble recovered | |
| RLB | Warrick Holdman | 31 | 7 | 16 | 1.0 sacks, 0 interceptions, 0 fumbles recovered | |
| LCB | Kenny Wright | 29 | 7 | 9 | 0.0 sacks, 1 interception, 0 fumbles recovered | |
| RCB | Carlos Rogers | 25 | 1 | 15 | 0.0 sacks, 1 interception, 0 fumbles recovered | |
| SS | Adam Archuleta | 29 | 5 | 7 | 1.0 sacks, 0 interceptions, 0 fumbles recovered | |
| FS | Sean Taylor* | 23 | 2 | 16 | 0.0 sacks, 1 interception, 0 fumbles recovered | |
Roster