| Rk | Day | Date | Tm | Opp | Tm | Opp | |||
|---|---|---|---|---|---|---|---|---|---|
| 1 | Sat | October 3, 1953 | W | Detroit Lions | @ | Baltimore Colts | 27 | 17 | boxscore |
| 2 | Sat | November 7, 1953 | W | Detroit Lions | Baltimore Colts | 17 | 7 | boxscore | |
| 3 | Sat | October 16, 1954 | W | Detroit Lions | Baltimore Colts | 35 | 0 | boxscore | |
| 4 | Sat | November 6, 1954 | W | Detroit Lions | @ | Baltimore Colts | 27 | 3 | boxscore |
| 5 | Sat | October 1, 1955 | L | Detroit Lions | @ | Baltimore Colts | 13 | 28 | boxscore |
| 6 | Sat | November 5, 1955 | W | Detroit Lions | Baltimore Colts | 24 | 14 | boxscore | |
| 7 | Sat | October 6, 1956 | W | Detroit Lions | @ | Baltimore Colts | 31 | 14 | boxscore |
| 8 | Sun | November 18, 1956 | W | Detroit Lions | Baltimore Colts | 27 | 3 | boxscore | |
| 9 | Sun | September 29, 1957 | L | Detroit Lions | @ | Baltimore Colts | 14 | 34 | boxscore |
| 10 | Sun | October 20, 1957 | W | Detroit Lions | Baltimore Colts | 31 | 27 | boxscore | |
| 11 | Sun | September 28, 1958 | L | Detroit Lions | @ | Baltimore Colts | 15 | 28 | boxscore |
| 12 | Sun | October 19, 1958 | L | Detroit Lions | Baltimore Colts | 14 | 40 | boxscore | |
| 13 | Sun | September 27, 1959 | L | Detroit Lions | @ | Baltimore Colts | 9 | 21 | boxscore |
| 14 | Sun | October 11, 1959 | L | Detroit Lions | Baltimore Colts | 24 | 31 | boxscore | |
| 15 | Sun | October 23, 1960 | W | Detroit Lions | Baltimore Colts | 30 | 17 | boxscore | |
| 16 | Sun | December 4, 1960 | W | Detroit Lions | @ | Baltimore Colts | 20 | 15 | boxscore |
| 17 | Sun | September 24, 1961 | W | Detroit Lions | @ | Baltimore Colts | 16 | 15 | boxscore |
| 18 | Sun | October 22, 1961 | L | Detroit Lions | Baltimore Colts | 14 | 17 | boxscore | |
| 19 | Sun | September 30, 1962 | W | Detroit Lions | @ | Baltimore Colts | 29 | 20 | boxscore |
| 20 | Sun | December 2, 1962 | W | Detroit Lions | Baltimore Colts | 21 | 14 | boxscore | |
| 21 | Sun | October 20, 1963 | L | Detroit Lions | Baltimore Colts | 21 | 25 | boxscore | |
| 22 | Sun | November 10, 1963 | L | Detroit Lions | @ | Baltimore Colts | 21 | 24 | boxscore |
| 23 | Sun | October 25, 1964 | L | Detroit Lions | Baltimore Colts | 0 | 34 | boxscore | |
| 24 | Sun | December 6, 1964 | W | Detroit Lions | @ | Baltimore Colts | 31 | 14 | boxscore |
| 25 | Sun | October 10, 1965 | L | Detroit Lions | @ | Baltimore Colts | 7 | 31 | boxscore |
| 26 | Thu | November 25, 1965 | T | Detroit Lions | Baltimore Colts | 24 | 24 | boxscore | |
| 27 | Sun | October 16, 1966 | L | Detroit Lions | @ | Baltimore Colts | 14 | 45 | boxscore |
| 28 | Sun | November 20, 1966 | W | Detroit Lions | Baltimore Colts | 20 | 14 | boxscore | |
| 29 | Sun | November 19, 1967 | L | Detroit Lions | @ | Baltimore Colts | 7 | 41 | boxscore |
| 30 | Sun | November 10, 1968 | L | Detroit Lions | Baltimore Colts | 10 | 27 | boxscore | |
| 31 | Sun | December 7, 1969 | T | Detroit Lions | @ | Baltimore Colts | 17 | 17 | boxscore |
| 32 | Sun | October 21, 1973 | L | Detroit Lions | Baltimore Colts | 27 | 29 | boxscore | |
| 33 | Sun | December 11, 1977 | W | Detroit Lions | @ | Baltimore Colts | 13 | 10 | boxscore |
| 34 | Sun | November 16, 1980 | L | Detroit Lions | Baltimore Colts | 9 | 10 | boxscore | |
| 35 | Sun | September 22, 1985 | L | Detroit Lions | @ | Indianapolis Colts | 6 | 14 | boxscore |
| 36 | Sun | September 22, 1991 | W | Detroit Lions | @ | Indianapolis Colts | 33 | 24 | boxscore |
| 37 | Sun | November 23, 1997 | W | Detroit Lions | Indianapolis Colts | 32 | 10 | boxscore | |
| 38 | Sun | October 29, 2000 | L | Detroit Lions | @ | Indianapolis Colts | 18 | 30 | boxscore |
| 39 | Thu | November 25, 2004 | L | Detroit Lions | Indianapolis Colts | 9 | 41 | boxscore | |
| 40 | Sun | December 14, 2008 | L | Detroit Lions | @ | Indianapolis Colts | 21 | 31 | boxscore |
| 41 | Sun | December 2, 2012 | L | Detroit Lions | Indianapolis Colts | 33 | 35 | boxscore |