| Week | Day | Date | Winner/tie | Loser/tie | PtsW | PtsL | YdsW | TOW | YdsL | TOL | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Sat | September 9 | boxscore | Houston Oilers | Oakland Raiders | 55 | 0 | 482 | 1 | 99 | 5 | |
| 1 | Sat | September 9 | boxscore | New York Titans | @ | Boston Patriots | 21 | 20 | 276 | 3 | 217 | 2 |
| 1 | Sun | September 10 | boxscore | Denver Broncos | @ | Buffalo Bills | 22 | 10 | 279 | 2 | 284 | 3 |
| 1 | Sun | September 10 | boxscore | San Diego Chargers | @ | Dallas Texans | 26 | 10 | 365 | 2 | 292 | 6 |
| Week | Day | Date | Winner/tie | Loser/tie | PtsW | PtsL | YdsW | TOW | YdsL | TOL | ||
| 2 | Sat | September 16 | boxscore | Boston Patriots | Denver Broncos | 45 | 17 | 392 | 1 | 270 | 4 | |
| 2 | Sun | September 17 | boxscore | Buffalo Bills | New York Titans | 41 | 31 | 288 | 3 | 316 | 4 | |
| 2 | Sun | September 17 | boxscore | San Diego Chargers | Oakland Raiders | 44 | 0 | 386 | 0 | 106 | 6 | |
| Week | Day | Date | Winner/tie | Loser/tie | PtsW | PtsL | YdsW | TOW | YdsL | TOL | ||
| 3 | Sat | September 23 | boxscore | Boston Patriots | @ | Buffalo Bills | 23 | 21 | 329 | 2 | 175 | 2 |
| 3 | Sun | September 24 | boxscore | Dallas Texans | @ | Oakland Raiders | 42 | 35 | 462 | 2 | 307 | 1 |
| 3 | Sun | September 24 | boxscore | San Diego Chargers | Houston Oilers | 34 | 24 | 158 | 1 | 372 | 7 | |
| 3 | Sun | September 24 | boxscore | New York Titans | Denver Broncos | 35 | 28 | 203 | 3 | 286 | 2 | |
| Week | Day | Date | Winner/tie | Loser/tie | PtsW | PtsL | YdsW | TOW | YdsL | TOL | ||
| 4 | Sat | September 30 | boxscore | San Diego Chargers | @ | Buffalo Bills | 19 | 11 | 302 | 1 | 239 | 2 |
| 3 | Sun | October 1 | boxscore | Dallas Texans | Houston Oilers | 26 | 21 | 528 | 0 | 353 | 5 | |
| 4 | Sun | October 1 | boxscore | New York Titans | Boston Patriots | 37 | 30 | 353 | 3 | 239 | 2 | |
| 4 | Sun | October 1 | boxscore | Oakland Raiders | Denver Broncos | 33 | 19 | 256 | 0 | 275 | 3 | |
| Week | Day | Date | Winner/tie | Loser/tie | PtsW | PtsL | YdsW | TOW | YdsL | TOL | ||
| 5 | Sat | October 7 | boxscore | San Diego Chargers | @ | Boston Patriots | 38 | 27 | 399 | 3 | 253 | 3 |
| 5 | Sun | October 8 | boxscore | Dallas Texans | @ | Denver Broncos | 19 | 12 | 230 | 1 | 271 | 6 |
| 4 | Sun | October 8 | boxscore | Buffalo Bills | @ | Houston Oilers | 22 | 12 | 382 | 5 | 194 | 3 |
| Week | Day | Date | Winner/tie | Loser/tie | PtsW | PtsL | YdsW | TOW | YdsL | TOL | ||
| 6 | Fri | October 13 | boxscore | Houston Oilers | @ | Boston Patriots | 31 | 31 | 540 | 2 | 383 | 2 |
| 5 | Sun | October 15 | boxscore | San Diego Chargers | @ | New York Titans | 25 | 10 | 422 | 5 | 202 | 5 |
| 6 | Sun | October 15 | boxscore | Buffalo Bills | Dallas Texans | 27 | 24 | 362 | 3 | 193 | 3 | |
| 6 | Sun | October 15 | boxscore | Denver Broncos | Oakland Raiders | 27 | 24 | 294 | 3 | 388 | 5 | |
| 6 | Sun | October 22 | boxscore | San Diego Chargers | @ | Oakland Raiders | 41 | 10 | 334 | 3 | 58 | 6 |
| 6 | Sun | October 22 | boxscore | Houston Oilers | Dallas Texans | 38 | 7 | 475 | 0 | 296 | 2 | |
| Week | Day | Date | Winner/tie | Loser/tie | PtsW | PtsL | YdsW | TOW | YdsL | TOL | ||
| 7 | Sun | October 22 | boxscore | Denver Broncos | New York Titans | 27 | 10 | 338 | 4 | 359 | 6 | |
| 7 | Sun | October 22 | boxscore | Boston Patriots | Buffalo Bills | 52 | 21 | 437 | 2 | 275 | 5 | |
| 7 | Sun | October 29 | boxscore | Boston Patriots | @ | Dallas Texans | 18 | 17 | 312 | 2 | 236 | 1 |
| 7 | Sun | October 29 | boxscore | New York Titans | @ | Oakland Raiders | 14 | 6 | 287 | 1 | 137 | 3 |
| Week | Day | Date | Winner/tie | Loser/tie | PtsW | PtsL | YdsW | TOW | YdsL | TOL | ||
| 8 | Sun | October 29 | boxscore | Houston Oilers | @ | Buffalo Bills | 28 | 16 | 510 | 4 | 351 | 4 |
| 8 | Sun | October 29 | boxscore | San Diego Chargers | Denver Broncos | 37 | 0 | 312 | 5 | 304 | 7 | |
| Week | Day | Date | Winner/tie | Loser/tie | PtsW | PtsL | YdsW | TOW | YdsL | TOL | ||
| 9 | Fri | November 3 | boxscore | Boston Patriots | Dallas Texans | 28 | 21 | 229 | 2 | 364 | 3 | |
| 9 | Sun | November 5 | boxscore | San Diego Chargers | New York Titans | 48 | 13 | 353 | 4 | 201 | 6 | |
| 9 | Sun | November 5 | boxscore | Oakland Raiders | @ | Buffalo Bills | 31 | 22 | 381 | 1 | 365 | 4 |
| 9 | Sun | November 5 | boxscore | Houston Oilers | @ | Denver Broncos | 55 | 14 | 582 | 2 | 204 | 6 |
| 9 | Sat | November 11 | boxscore | New York Titans | Oakland Raiders | 23 | 12 | 353 | 6 | 310 | 6 | |
| 9 | Sun | November 12 | boxscore | Buffalo Bills | @ | Dallas Texans | 30 | 20 | 169 | 3 | 280 | 6 |
| Week | Day | Date | Winner/tie | Loser/tie | PtsW | PtsL | YdsW | TOW | YdsL | TOL | ||
| 10 | Sun | November 12 | boxscore | San Diego Chargers | @ | Denver Broncos | 19 | 16 | 209 | 3 | 358 | 5 |
| 9 | Sun | November 12 | boxscore | Houston Oilers | Boston Patriots | 27 | 15 | 346 | 2 | 252 | 3 | |
| Week | Day | Date | Winner/tie | Loser/tie | PtsW | PtsL | YdsW | TOW | YdsL | TOL | ||
| 11 | Fri | November 17 | boxscore | Boston Patriots | Oakland Raiders | 20 | 17 | 225 | 2 | 203 | 2 | |
| 10 | Sun | November 19 | boxscore | Houston Oilers | New York Titans | 49 | 13 | 555 | 1 | 347 | 4 | |
| 11 | Sun | November 19 | boxscore | San Diego Chargers | Dallas Texans | 24 | 14 | 338 | 3 | 288 | 3 | |
| 11 | Sun | November 19 | boxscore | Buffalo Bills | @ | Denver Broncos | 23 | 10 | 235 | 0 | 273 | 9 |
| 11 | Thu | November 23 | boxscore | New York Titans | Buffalo Bills | 21 | 14 | 216 | 2 | 277 | 3 | |
| 11 | Sun | November 26 | boxscore | Dallas Texans | Oakland Raiders | 43 | 11 | 495 | 4 | 254 | 5 | |
| 11 | Sun | November 26 | boxscore | Houston Oilers | Denver Broncos | 45 | 14 | 311 | 6 | 159 | 8 | |
| Week | Day | Date | Winner/tie | Loser/tie | PtsW | PtsL | YdsW | TOW | YdsL | TOL | ||
| 12 | Sun | December 3 | boxscore | Houston Oilers | San Diego Chargers | 33 | 13 | 473 | 3 | 306 | 4 | |
| 12 | Sun | December 3 | boxscore | New York Titans | Dallas Texans | 28 | 7 | 393 | 2 | 357 | 7 | |
| Week | Day | Date | Winner/tie | Loser/tie | PtsW | PtsL | YdsW | TOW | YdsL | TOL | ||
| 13 | Sun | December 3 | boxscore | Boston Patriots | @ | Denver Broncos | 28 | 24 | 244 | 2 | 281 | 4 |
| 12 | Sun | December 3 | boxscore | Buffalo Bills | @ | Oakland Raiders | 26 | 21 | 269 | 1 | 317 | 2 |
| 13 | Sat | December 9 | boxscore | Boston Patriots | @ | Oakland Raiders | 35 | 21 | 407 | 2 | 213 | 2 |
| 13 | Sun | December 10 | boxscore | Houston Oilers | @ | New York Titans | 48 | 21 | 573 | 1 | 304 | 3 |
| 13 | Sun | December 10 | boxscore | Dallas Texans | Denver Broncos | 49 | 21 | 413 | 3 | 219 | 5 | |
| 13 | Sun | December 10 | boxscore | San Diego Chargers | Buffalo Bills | 28 | 10 | 237 | 2 | 279 | 4 | |
| Week | Day | Date | Winner/tie | Loser/tie | PtsW | PtsL | YdsW | TOW | YdsL | TOL | ||
| 14 | Sun | December 17 | boxscore | Boston Patriots | @ | San Diego Chargers | 41 | 0 | 295 | 3 | 192 | 6 |
| 14 | Sun | December 17 | boxscore | Houston Oilers | @ | Oakland Raiders | 47 | 16 | 522 | 2 | 256 | 1 |
| 14 | Sun | December 17 | boxscore | Dallas Texans | New York Titans | 35 | 24 | 325 | 4 | 255 | 4 | |
| Playoffs | ||||||||||||
| ConfChamp | December 24 | boxscore | Houston Oilers | @ | San Diego Chargers | 10 | 3 | 256 | 7 | 256 | 6 |