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- March 14, 2018: Traded Cordy Glenn, 2018 1st round pick (21st overall, Billy Price) and 2018 5th round pick (158th overall, Andrew Brown) to Bengals for 2018 1st round pick (12th overall subsequently traded, Vita Vea) and 2018 6th round pick (187th overall, Ray-Ray McCloud)
- March 14, 2018: Traded Tyrod Taylor to Browns for 2018 3rd round pick (65th overall subsequently traded, Brandon Parker)
- April 26, 2018: Traded 2018 1st round pick (22nd overall subsequently traded, Rashaan Evans), 2018 3rd round pick (65th overall subsequently traded, Brandon Parker) and 2018 5th round pick (154th overall subsequently traded, Siran Neal) to Ravens for 2018 1st round pick (16th overall, Tremaine Edmunds)
- April 26, 2018: Traded 2018 1st round pick (12th overall, Vita Vea), 2018 2nd round pick (53rd overall, M.J. Stewart) and 2018 2nd round pick (56th overall subsequently traded, Duke Dawson) to Buccaneers for 2018 1st round pick (7th overall, Josh Allen)
- August 5, 2018: Traded a 2020 7th round pick to Browns for Corey Coleman
- September 2, 2018: Traded A.J. McCarron to Raiders for 2019 5th round pick (158th overall subsequently traded, Michael Jackson)
- September 25, 2018: Traded Marshall Newhouse to Panthers for a conditional 2021 pick (late-round)