| Offensive Starters | | | | | |
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| QB | Baker Mayfield | 25 | 2 | 16 | 305 for 486, 3,563 yards, 26 td, 8 int, & 54 rushes for 165 yards and 1 td | Cleveland Browns / 1st / 1st pick / 2018 |
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| RB | Nick Chubb* | 25 | 2 | 12 | 190 rushes for 1,067 yards, 12 td, & 16 catches for 150 yards and 0 td | Cleveland Browns / 2nd / 35th pick / 2018 |
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| WR | Jarvis Landry | 28 | 6 | 14 | 72 catches for 840 yards, 3 td, & 4 rushes for 10 yards and 1 td | Miami Dolphins / 2nd / 63rd pick / 2014 |
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| TE | Austin Hooper | 26 | 4 | 13 | 46 catches for 435 yards, 4 td | Atlanta Falcons / 3rd / 81st pick / 2016 |
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| T | Jack Conklin+ | 26 | 4 | 15 | | Tennessee Titans / 1st / 8th pick / 2016 |
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| T | Jedrick Wills Jr. | 21 | Rook | 15 | | Cleveland Browns / 1st / 10th pick / 2020 |
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| G | Joel Bitonio* | 29 | 6 | 16 | | Cleveland Browns / 2nd / 35th pick / 2014 |
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| G | Wyatt Teller | 26 | 2 | 11 | | Buffalo Bills / 5th / 166th pick / 2018 |
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| C | J.C. Tretter | 29 | 7 | 16 | | Green Bay Packers / 4th / 122nd pick / 2013 |
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| Defensive Starters | | | | | |
|---|
| DE | Myles Garrett *+ | 25 | 3 | 14 | | Cleveland Browns / 1st / 1st pick / 2017 |
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| DE | Olivier Vernon | 30 | 8 | 13 | | Miami Dolphins / 3rd / 72nd pick / 2012 |
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| DT | Larry Ogunjobi | 26 | 3 | 15 | | Cleveland Browns / 3rd / 65th pick / 2017 |
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| DT | Sheldon Richardson | 30 | 7 | 16 | | New York Jets / 1st / 13th pick / 2013 |
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| OLB | Sione Takitaki | 25 | 1 | 12 | | Cleveland Browns / 3rd / 80th pick / 2019 |
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| ILB | B.J. Goodson | 27 | 4 | 14 | | New York Giants / 4th / 109th pick / 2016 |
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| CB | Terrance Mitchell | 28 | 6 | 16 | | Dallas Cowboys / 7th / 254th pick / 2014 |
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| CB | Denzel Ward | 23 | 2 | 12 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | Cleveland Browns / 1st / 4th pick / 2018 |
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| FS | Andrew Sendejo | 33 | 10 | 14 | | |
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