| Offensive Starters | | | | | |
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| QB | Matthew Stafford | 30 | 9 | 13 | 307 for 462, 3,187 yards, 18 td, 11 int, & 23 rushes for 73 yards and 0 td | Detroit Lions / 1st / 1st pick / 2009 |
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| WR | Kenny Golladay | 25 | 1 | 11 | 57 catches for 859 yards, 5 td, & 1 rush for 8 yards and 0 td | Detroit Lions / 3rd / 96th pick / 2017 |
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| WR | Marvin Jones | 28 | 6 | 9 | 35 catches for 508 yards, 5 td | Cincinnati Bengals / 5th / 166th pick / 2012 |
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| WR | Sam Martin | 28 | 5 | 0 | | Detroit Lions / 5th / 165th pick / 2013 |
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| TE | Levine Toilolo | 27 | 5 | 7 | 12 catches for 176 yards, 0 td | Atlanta Falcons / 4th / 133rd pick / 2013 |
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| TE | Luke Willson | 28 | 5 | 8 | 13 catches for 87 yards, 0 td | Seattle Seahawks / 5th / 158th pick / 2013 |
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| LT | Taylor Decker | 25 | 2 | 13 | | Detroit Lions / 1st / 16th pick / 2016 |
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| LG | Frank Ragnow | 22 | Rook | 13 | | Detroit Lions / 1st / 20th pick / 2018 |
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| C | Graham Glasgow | 26 | 2 | 13 | | Detroit Lions / 3rd / 95th pick / 2016 |
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| RG | Kenny Wiggins | 30 | 7 | 7 | | |
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| RT | Ricky Wagner | 29 | 5 | 13 | | Baltimore Ravens / 5th / 168th pick / 2013 |
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| Defensive Starters | | | | | |
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| DE | Romeo Okwara | 23 | 2 | 11 | | |
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| DT | Ricky Jean-Francois | 32 | 9 | 8 | | San Francisco 49ers / 7th / 244th pick / 2009 |
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| MLB | Jarrad Davis | 23 | 1 | 13 | 5.0 sacks, 0 interceptions, 1 fumble recovered | Detroit Lions / 1st / 21st pick / 2017 |
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| LB | Christian Jones | 27 | 4 | 13 | | |
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| LB | Devon Kennard | 27 | 4 | 12 | | New York Giants / 5th / 174th pick / 2014 |
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| CB | Nevin Lawson | 27 | 4 | 12 | | Detroit Lions / 4th / 133rd pick / 2014 |
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| CB | Darius Slay | 27 | 5 | 12 | 0.0 sacks, 3 interceptions, 0 fumbles recovered | Detroit Lions / 2nd / 36th pick / 2013 |
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| SS | Quandre Diggs | 25 | 3 | 13 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | Detroit Lions / 6th / 200th pick / 2015 |
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| FS | Glover Quin | 32 | 9 | 13 | 1.0 sacks, 0 interceptions, 0 fumbles recovered | Houston Texans / 4th / 112th pick / 2009 |
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| Special Teams Starters | | | | | |
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| K | Matt Prater | 34 | 11 | 0 | 24 of 27 field goals & 25 of 25 extra points | |
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| P | Sam Martin | 28 | 5 | 0 | 57 punts for a 45.3 average, 0 blocked | Detroit Lions / 5th / 165th pick / 2013 |
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