| Single-season | Passing | Rushing | Receiving | Returns | Kicking | Scoring | |
| Career | Passing | Rushing | Receiving | Returns | Kicking | Scoring | Defense |
| Rk | Year | Age | Tm | Pos | G | GS | Cmp | Att | Yds | TD | Int | Lng | Sk | Yds | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Drew Bledsoe | 2002* | 30 | BUF | QB | 16 | 16 | 375 | 610 | 61.5 | 4359 | 24 | 3.9 | 15 | 2.5 | 73 | 7.1 | 6.4 | 11.6 | 272.4 | 86.0 | 54 | 369 | 6.0 | 5.4 | 8.1 |
| 2 | Joe Ferguson | 1983 | 33 | BUF | QB | 16 | 16 | 281 | 508 | 55.3 | 2995 | 26 | 5.1 | 25 | 4.9 | 43 | 5.9 | 4.2 | 10.7 | 187.2 | 69.3 | 27 | 266 | 5.1 | 3.5 | 5.0 |
| 3 | Joe Ferguson | 1981 | 31 | BUF | QB | 16 | 16 | 252 | 498 | 50.6 | 3652 | 24 | 4.8 | 20 | 4.0 | 67 | 7.3 | 6.0 | 14.5 | 228.3 | 74.1 | 15 | 137 | 6.9 | 5.6 | 2.9 |
| 4 | Jim Kelly | 1986 | 26 | BUF | QB | 16 | 16 | 285 | 480 | 59.4 | 3593 | 22 | 4.6 | 17 | 3.5 | 84 | 7.5 | 6.4 | 12.6 | 224.6 | 83.3 | 43 | 330 | 6.2 | 5.2 | 8.2 |
| 5 | Doug Flutie | 1999 | 37 | BUF | QB | 15 | 15 | 264 | 478 | 55.2 | 3171 | 19 | 4.0 | 16 | 3.3 | 54 | 6.6 | 5.5 | 12.0 | 211.4 | 75.1 | 26 | 176 | 5.9 | 4.9 | 5.2 |
| 6 | Jim Kelly | 1991*+ | 31 | BUF | QB | 15 | 15 | 304 | 474 | 64.1 | 3844 | 33 | 7.0 | 17 | 3.6 | 77 | 8.1 | 7.2 | 12.6 | 256.3 | 97.6 | 31 | 227 | 7.2 | 6.3 | 6.1 |
| 7 | Drew Bledsoe | 2003 | 31 | BUF | QB | 16 | 16 | 274 | 471 | 58.2 | 2860 | 11 | 2.3 | 12 | 2.5 | 54 | 6.1 | 5.2 | 10.4 | 178.8 | 73.0 | 49 | 371 | 4.8 | 4.0 | 9.4 |
| 8 | Jim Kelly | 1993 | 33 | BUF | QB | 16 | 16 | 288 | 470 | 61.3 | 3382 | 18 | 3.8 | 18 | 3.8 | 65 | 7.2 | 5.9 | 11.7 | 211.4 | 79.9 | 25 | 171 | 6.5 | 5.2 | 5.1 |
| 9 | Jim Kelly | 1992* | 32 | BUF | QB | 16 | 16 | 269 | 462 | 58.2 | 3457 | 23 | 5.0 | 19 | 4.1 | 65 | 7.5 | 6.1 | 12.9 | 216.1 | 81.2 | 20 | 145 | 6.9 | 5.6 | 4.1 |
| 10 | Joe Ferguson | 1979 | 29 | BUF | QB | 16 | 16 | 238 | 458 | 52.0 | 3572 | 14 | 3.1 | 15 | 3.3 | 84 | 7.8 | 6.6 | 15.0 | 223.3 | 74.4 | 43 | 387 | 6.4 | 5.3 | 8.6 |
| 11 | Jim Kelly | 1995 | 35 | BUF | QB | 15 | 15 | 255 | 458 | 55.7 | 3130 | 22 | 4.8 | 13 | 2.8 | 77 | 6.8 | 6.0 | 12.3 | 208.7 | 81.1 | 26 | 181 | 6.1 | 5.3 | 5.4 |
| 12 | Joe Ferguson | 1977 | 27 | BUF | QB | 14 | 14 | 221 | 457 | 48.4 | 2803 | 12 | 2.6 | 24 | 5.3 | 42 | 6.1 | 4.0 | 12.7 | 200.2 | 54.8 | 36 | 273 | 5.1 | 3.2 | 7.3 |
| 13 | Jim Kelly | 1988 | 28 | BUF | QB | 16 | 16 | 269 | 452 | 59.5 | 3380 | 15 | 3.3 | 17 | 3.8 | 66 | 7.5 | 6.1 | 12.6 | 211.3 | 78.2 | 30 | 229 | 6.5 | 5.3 | 6.2 |
| 14 | Drew Bledsoe | 2004 | 32 | BUF | QB | 16 | 16 | 256 | 450 | 56.9 | 2932 | 20 | 4.4 | 16 | 3.6 | 69 | 6.5 | 5.4 | 11.5 | 183.3 | 76.6 | 37 | 215 | 5.6 | 4.5 | 7.6 |
| 15 | Jim Kelly | 1994 | 34 | BUF | QB | 14 | 14 | 285 | 448 | 63.6 | 3114 | 22 | 4.9 | 17 | 3.8 | 83 | 7.0 | 5.7 | 10.9 | 222.4 | 84.6 | 34 | 244 | 6.0 | 4.8 | 7.1 |
| 16 | Joe Ferguson | 1980 | 30 | BUF | QB | 16 | 16 | 251 | 439 | 57.2 | 2805 | 20 | 4.6 | 18 | 4.1 | 69 | 6.4 | 5.0 | 11.2 | 175.3 | 74.5 | 13 | 129 | 5.9 | 4.6 | 2.9 |
| 17 | J.P. Losman | 2006 | 25 | BUF | QB | 16 | 16 | 268 | 429 | 62.5 | 3051 | 19 | 4.4 | 14 | 3.3 | 83 | 7.1 | 6.1 | 11.4 | 190.7 | 84.9 | 47 | 332 | 5.7 | 4.8 | 9.9 |
| 18 | Jim Kelly | 1987* | 27 | BUF | QB | 12 | 12 | 250 | 419 | 59.7 | 2798 | 19 | 4.5 | 11 | 2.6 | 47 | 6.7 | 5.9 | 11.2 | 233.2 | 83.8 | 27 | 239 | 5.7 | 5.1 | 6.1 |
| 19 | Todd Collins | 1997 | 26 | BUF | QB | 14 | 13 | 215 | 391 | 55.0 | 2367 | 12 | 3.1 | 13 | 3.3 | 77 | 6.1 | 4.9 | 11.0 | 169.1 | 69.5 | 39 | 278 | 4.9 | 3.8 | 9.1 |
| 20 | Jim Kelly | 1989 | 29 | BUF | QB | 13 | 13 | 228 | 391 | 58.3 | 3130 | 25 | 6.4 | 18 | 4.6 | 78 | 8.0 | 6.6 | 13.7 | 240.8 | 86.2 | 30 | 216 | 6.9 | 5.6 | 7.1 |
| 21 | Jack Kemp | 1965*+ | 30 | BUF | QB | 14 | 13 | 179 | 391 | 45.8 | 2368 | 10 | 2.6 | 18 | 4.6 | 78 | 6.1 | 4.2 | 13.2 | 169.1 | 54.8 | |||||
| 22 | Jack Kemp | 1966* | 31 | BUF | QB | 14 | 14 | 166 | 389 | 42.7 | 2451 | 11 | 2.8 | 16 | 4.1 | 55 | 6.3 | 4.7 | 14.8 | 175.1 | 56.2 | |||||
| 23 | Jack Kemp | 1963* | 28 | BUF | QB | 14 | 12 | 193 | 384 | 50.3 | 2910 | 13 | 3.4 | 20 | 5.2 | 89 | 7.6 | 5.6 | 15.1 | 207.9 | 65.1 | |||||
| 24 | Jim Kelly | 1996 | 36 | BUF | QB | 13 | 13 | 222 | 379 | 58.6 | 2810 | 14 | 3.7 | 19 | 5.0 | 67 | 7.4 | 5.5 | 12.7 | 216.2 | 73.2 | 37 | 287 | 6.1 | 4.3 | 8.9 |
| 25 | Jack Kemp | 1967 | 32 | BUF | QB | 14 | 11 | 161 | 369 | 43.6 | 2503 | 14 | 3.8 | 26 | 7.0 | 63 | 6.8 | 4.0 | 15.5 | 178.8 | 50.0 | |||||
| 26 | Doug Flutie | 1998* | 36 | BUF | QB | 13 | 10 | 202 | 354 | 57.1 | 2711 | 20 | 5.6 | 11 | 3.1 | 84 | 7.7 | 6.8 | 13.4 | 208.5 | 87.4 | 12 | 78 | 7.2 | 6.4 | 3.3 |
| 27 | Jim Kelly | 1990* | 30 | BUF | QB | 14 | 14 | 219 | 346 | 63.3 | 2829 | 24 | 6.9 | 9 | 2.6 | 71 | 8.2 | 7.7 | 12.9 | 202.1 | 101.2 | 20 | 158 | 7.3 | 6.8 | 5.5 |
| 28 | Joe Ferguson | 1984 | 34 | BUF | QB | 12 | 11 | 191 | 344 | 55.5 | 1991 | 12 | 3.5 | 17 | 4.9 | 68 | 5.8 | 3.9 | 10.4 | 165.9 | 63.5 | 35 | 357 | 4.3 | 2.6 | 9.2 |
| 29 | Jack Kemp | 1969* | 34 | BUF | QB | 14 | 11 | 170 | 344 | 49.4 | 1981 | 13 | 3.8 | 22 | 6.4 | 55 | 5.8 | 3.3 | 11.7 | 141.5 | 53.2 | 21 | 187 | 4.9 | 2.6 | 5.8 |
| Rk | Year | Age | Tm | Pos | G | GS | Cmp | Att | Yds | TD | Int | Lng | Sk | Yds | ||||||||||||
| 30 | Joe Ferguson | 1978 | 28 | BUF | QB | 16 | 16 | 175 | 330 | 53.0 | 2136 | 16 | 4.8 | 15 | 4.5 | 92 | 6.5 | 4.9 | 12.2 | 133.5 | 70.5 | 29 | 243 | 5.3 | 3.8 | 8.1 |
| 31 | Joe Ferguson | 1975 | 25 | BUF | QB | 14 | 14 | 169 | 321 | 52.6 | 2426 | 25 | 7.8 | 17 | 5.3 | 77 | 7.6 | 6.0 | 14.4 | 173.3 | 81.3 | 20 | 153 | 6.7 | 5.2 | 5.9 |
| 32 | Dennis Shaw | 1970 | 23 | BUF | QB | 14 | 12 | 178 | 321 | 55.5 | 2507 | 10 | 3.1 | 20 | 6.2 | 48 | 7.8 | 5.3 | 14.1 | 179.1 | 65.3 | 41 | 387 | 5.9 | 3.6 | 11.3 |
| 33 | Alex Van Pelt | 2001 | 31 | BUF | qb | 12 | 8 | 178 | 307 | 58.0 | 2056 | 12 | 3.9 | 11 | 3.6 | 80 | 6.7 | 5.5 | 11.6 | 171.3 | 76.4 | 14 | 73 | 6.2 | 5.0 | 4.4 |
| 34 | Rob Johnson | 2000 | 27 | BUF | QB | 12 | 11 | 175 | 306 | 57.2 | 2125 | 12 | 3.9 | 7 | 2.3 | 74 | 6.9 | 6.3 | 12.1 | 177.1 | 82.2 | 49 | 292 | 5.2 | 4.6 | 13.8 |
| 35 | Dennis Shaw | 1971 | 24 | BUF | QB | 13 | 12 | 149 | 291 | 51.2 | 1813 | 11 | 3.8 | 26 | 8.9 | 75 | 6.2 | 2.6 | 12.2 | 139.5 | 46.1 | 33 | 276 | 4.7 | 1.5 | 10.2 |
| 36 | Vince Ferragamo | 1985 | 31 | BUF | QB | 10 | 9 | 149 | 287 | 51.9 | 1677 | 5 | 1.7 | 17 | 5.9 | 48 | 5.8 | 3.4 | 11.3 | 167.7 | 50.8 | 19 | 135 | 5.0 | 2.7 | 6.2 |
| 37 | Trent Edwards | 2007 | 24 | BUF | QB | 10 | 9 | 151 | 269 | 56.1 | 1630 | 7 | 2.6 | 8 | 3.0 | 70 | 6.1 | 5.0 | 10.8 | 163.0 | 70.4 | 12 | 105 | 5.4 | 4.4 | 4.3 |
| 38 | Jack Kemp | 1964* | 29 | BUF | QB | 14 | 13 | 119 | 269 | 44.2 | 2285 | 13 | 4.8 | 26 | 9.7 | 94 | 8.5 | 4.6 | 19.2 | 163.2 | 50.9 | |||||
| 39 | Joe Ferguson | 1982 | 32 | BUF | QB | 9 | 9 | 144 | 264 | 54.5 | 1597 | 7 | 2.7 | 16 | 6.1 | 47 | 6.0 | 3.6 | 11.1 | 177.4 | 56.3 | 11 | 105 | 5.4 | 3.1 | 4.0 |
| 40 | Dennis Shaw | 1972 | 25 | BUF | QB | 14 | 13 | 136 | 258 | 52.7 | 1666 | 14 | 5.4 | 17 | 6.6 | 58 | 6.5 | 4.0 | 12.3 | 119.0 | 63.5 | 38 | 320 | 4.5 | 2.4 | 12.8 |
| 41 | Joe Ferguson | 1974 | 24 | BUF | QB | 14 | 14 | 119 | 232 | 51.3 | 1588 | 12 | 5.2 | 12 | 5.2 | 55 | 6.8 | 5.0 | 13.3 | 113.4 | 69.0 | 32 | 235 | 5.1 | 3.5 | 12.1 |
| 42 | Gary Marangi | 1976 | 24 | BUF | QB | 11 | 7 | 82 | 232 | 35.3 | 998 | 7 | 3.0 | 16 | 6.9 | 39 | 4.3 | 1.5 | 12.2 | 90.7 | 30.8 | 22 | 166 | 3.3 | 0.7 | 8.7 |
| 43 | Doug Flutie | 2000 | 38 | BUF | qb | 11 | 5 | 132 | 231 | 57.1 | 1700 | 8 | 3.5 | 3 | 1.3 | 52 | 7.4 | 7.1 | 12.9 | 154.5 | 86.5 | 10 | 68 | 6.8 | 6.5 | 4.1 |
| 44 | Kelly Holcomb | 2005 | 32 | BUF | QB | 10 | 8 | 155 | 230 | 67.4 | 1509 | 10 | 4.3 | 8 | 3.5 | 65 | 6.6 | 5.4 | 9.7 | 150.9 | 85.6 | 17 | 140 | 5.5 | 4.5 | 6.9 |
| 45 | Johnny Green | 1960 | 23 | BUF | QB | 10 | 6 | 89 | 228 | 39.0 | 1267 | 10 | 4.4 | 10 | 4.4 | 70 | 5.6 | 4.0 | 14.2 | 126.7 | 54.1 | |||||
| 46 | J.P. Losman | 2005 | 24 | BUF | qb | 9 | 8 | 113 | 228 | 49.6 | 1340 | 8 | 3.5 | 8 | 3.5 | 58 | 5.9 | 4.6 | 11.9 | 148.9 | 64.9 | 26 | 197 | 4.5 | 3.4 | 10.2 |
| 47 | Bruce Mathison | 1985 | 26 | BUF | qb | 10 | 7 | 113 | 228 | 49.6 | 1635 | 4 | 1.8 | 14 | 6.1 | 60 | 7.2 | 4.6 | 14.5 | 163.5 | 53.5 | 22 | 203 | 5.7 | 3.4 | 8.8 |
| 48 | Rob Johnson | 2001 | 28 | BUF | QB | 8 | 8 | 134 | 216 | 62.0 | 1465 | 5 | 2.3 | 7 | 3.2 | 61 | 6.8 | 5.6 | 10.9 | 183.1 | 76.3 | 31 | 196 | 5.1 | 4.1 | 12.6 |
| 49 | Dan Darragh | 1968 | 22 | BUF | QB | 11 | 7 | 92 | 215 | 42.8 | 917 | 3 | 1.4 | 14 | 6.5 | 41 | 4.3 | 1.5 | 10.0 | 83.4 | 33.0 | |||||
| 50 | M.C. Reynolds | 1961 | 26 | BUF | 12 | 3 | 83 | 181 | 45.9 | 1004 | 2 | 1.1 | 13 | 7.2 | 52 | 5.5 | 2.4 | 12.1 | 83.7 | 37.2 | ||||||
| 51 | Warren Rabb | 1962 | 25 | BUF | QB | 14 | 7 | 67 | 177 | 37.9 | 1196 | 10 | 5.6 | 14 | 7.9 | 76 | 6.8 | 3.8 | 17.9 | 85.4 | 47.7 | |||||
| 52 | J.P. Losman | 2007 | 26 | BUF | qb | 8 | 7 | 111 | 175 | 63.4 | 1204 | 4 | 2.3 | 6 | 3.4 | 85 | 6.9 | 5.6 | 10.8 | 150.5 | 76.9 | 14 | 103 | 5.8 | 4.6 | 7.4 |
| 53 | Joe Ferguson | 1973 | 23 | BUF | QB | 14 | 14 | 73 | 164 | 44.5 | 939 | 4 | 2.4 | 10 | 6.1 | 42 | 5.7 | 3.2 | 12.9 | 67.1 | 45.8 | 20 | 164 | 4.2 | 2.0 | 10.9 |
| 54 | Joe Ferguson | 1976 | 26 | BUF | qb | 7 | 7 | 74 | 151 | 49.0 | 1086 | 9 | 6.0 | 1 | 0.7 | 58 | 7.2 | 7.5 | 14.7 | 155.1 | 90.0 | 11 | 80 | 6.2 | 6.5 | 6.8 |
| 55 | Joe Dufek | 1984 | 23 | BUF | qb | 5 | 5 | 74 | 150 | 49.3 | 829 | 4 | 2.7 | 8 | 5.3 | 64 | 5.5 | 3.4 | 11.2 | 165.8 | 52.9 | 10 | 86 | 4.6 | 2.6 | 6.3 |
| 56 | Tommy O'Connell | 1960 | 30 | BUF | qb | 14 | 5 | 65 | 145 | 44.8 | 1033 | 7 | 4.8 | 13 | 9.0 | 64 | 7.1 | 3.6 | 15.9 | 73.8 | 47.9 | |||||
| 57 | Daryle Lamonica | 1964 | 23 | BUF | 14 | 1 | 55 | 128 | 43.0 | 1137 | 6 | 4.7 | 8 | 6.3 | 80 | 8.9 | 6.5 | 20.7 | 81.2 | 64.5 | ||||||
| 58 | Johnny Green | 1961 | 24 | BUF | QB | 8 | 5 | 56 | 126 | 44.4 | 903 | 6 | 4.8 | 5 | 4.0 | 61 | 7.2 | 5.9 | 16.1 | 112.9 | 68.3 | |||||
| 59 | Alex Van Pelt | 1997 | 27 | BUF | 6 | 3 | 60 | 124 | 48.4 | 684 | 2 | 1.6 | 10 | 8.1 | 39 | 5.5 | 2.0 | 11.4 | 114.0 | 37.2 | 4 | 33 | 5.1 | 1.7 | 3.1 | |
| Rk | Year | Age | Tm | Pos | G | GS | Cmp | Att | Yds | TD | Int | Lng | Sk | Yds | ||||||||||||
| 60 | Rob Johnson | 1998 | 25 | BUF | qb | 8 | 6 | 67 | 107 | 62.6 | 910 | 8 | 7.5 | 3 | 2.8 | 66 | 8.5 | 8.0 | 13.6 | 113.8 | 102.9 | 29 | 163 | 5.5 | 5.1 | 21.3 |
| 61 | James Harris | 1971 | 24 | BUF | 7 | 2 | 51 | 103 | 49.5 | 512 | 1 | 1.0 | 6 | 5.8 | 62 | 5.0 | 2.4 | 10.0 | 73.1 | 43.0 | 16 | 145 | 3.1 | 0.9 | 13.4 | |
| 62 | Ed Rutkowski | 1968 | 27 | BUF | qb | 13 | 3 | 41 | 100 | 41.0 | 380 | 0 | 0.0 | 6 | 6.0 | 37 | 3.8 | 1.1 | 9.3 | 29.2 | 27.1 | |||||
| 63 | Todd Collins | 1996 | 25 | BUF | 7 | 3 | 55 | 99 | 55.6 | 739 | 4 | 4.0 | 5 | 5.1 | 95 | 7.5 | 5.6 | 13.4 | 105.6 | 71.9 | 11 | 53 | 6.2 | 4.6 | 10.0 | |
| 64 | Jack Kemp | 1962* | 27 | BUF | 4 | 3 | 51 | 94 | 54.3 | 636 | 3 | 3.2 | 4 | 4.3 | 31 | 6.8 | 5.2 | 12.5 | 159.0 | 68.4 | ||||||
| 65 | Matt Kofler | 1984 | 25 | BUF | 16 | 0 | 33 | 93 | 35.5 | 432 | 2 | 2.2 | 5 | 5.4 | 70 | 4.6 | 2.4 | 13.1 | 27.0 | 35.8 | 15 | 111 | 3.0 | 1.1 | 13.9 | |
| 66 | Frank Reich | 1994 | 33 | BUF | 16 | 2 | 56 | 93 | 60.2 | 568 | 1 | 1.1 | 4 | 4.3 | 47 | 6.1 | 4.3 | 10.1 | 35.5 | 63.4 | 7 | 57 | 5.1 | 3.4 | 7.0 | |
| 67 | Frank Reich | 1989 | 28 | BUF | 7 | 3 | 53 | 87 | 60.9 | 701 | 7 | 8.0 | 2 | 2.3 | 63 | 8.1 | 7.8 | 13.2 | 100.1 | 103.7 | 4 | 24 | 7.4 | 7.2 | 4.4 | |
| 68 | Daryle Lamonica | 1966 | 25 | BUF | 14 | 0 | 33 | 84 | 39.3 | 549 | 4 | 4.8 | 5 | 6.0 | 55 | 6.5 | 4.3 | 16.6 | 39.2 | 53.1 | ||||||
| 69 | Kay Stephenson | 1968 | 24 | BUF | 10 | 3 | 29 | 79 | 36.7 | 364 | 4 | 5.1 | 7 | 8.9 | 55 | 4.6 | 1.1 | 12.6 | 36.4 | 31.8 | ||||||
| 70 | Al Dorow | 1962 | 33 | BUF | 4 | 4 | 30 | 75 | 40.0 | 333 | 2 | 2.7 | 7 | 9.3 | 34 | 4.4 | 0.5 | 11.1 | 83.3 | 23.9 | ||||||
| 71 | Warren Rabb | 1961 | 24 | BUF | 9 | 3 | 34 | 74 | 45.9 | 586 | 5 | 6.8 | 2 | 2.7 | 76 | 7.9 | 7.4 | 17.2 | 65.1 | 84.6 | ||||||
| 72 | Daryle Lamonica | 1963 | 22 | BUF | P | 14 | 2 | 33 | 71 | 46.5 | 437 | 3 | 4.2 | 4 | 5.6 | 93 | 6.2 | 4.0 | 13.2 | 31.2 | 57.1 | |||||
| 73 | Daryle Lamonica | 1965* | 24 | BUF | 14 | 1 | 29 | 70 | 41.4 | 376 | 3 | 4.3 | 6 | 8.6 | 74 | 5.4 | 1.9 | 13.0 | 26.9 | 37.6 | ||||||
| 74 | Tom Flores | 1967 | 30 | BUF | 14 | 3 | 22 | 64 | 34.4 | 260 | 0 | 0.0 | 8 | 12.5 | 59 | 4.1 | -1.6 | 11.8 | 18.6 | 8.1 | ||||||
| 75 | Frank Reich | 1990 | 29 | BUF | 16 | 2 | 36 | 63 | 57.1 | 469 | 2 | 3.2 | 0 | 0.0 | 43 | 7.4 | 7.8 | 13.0 | 29.3 | 91.3 | 6 | 41 | 6.2 | 6.5 | 8.7 | |
| 76 | Matt Kofler | 1983 | 24 | BUF | 16 | 0 | 35 | 61 | 57.4 | 440 | 4 | 6.6 | 3 | 4.9 | 28 | 7.2 | 5.7 | 12.6 | 27.5 | 81.3 | 10 | 85 | 5.0 | 3.7 | 14.1 | |
| 77 | Dan Darragh | 1969 | 23 | BUF | 3 | 2 | 24 | 52 | 46.2 | 365 | 1 | 1.9 | 6 | 11.5 | 53 | 7.0 | 2.0 | 15.2 | 121.7 | 36.6 | 11 | 103 | 4.2 | 0.0 | 17.5 | |
| 78 | James Harris | 1970 | 23 | BUF | 7 | 0 | 24 | 50 | 48.0 | 338 | 3 | 6.0 | 4 | 8.0 | 32 | 6.8 | 3.8 | 14.1 | 48.3 | 56.9 | 7 | 63 | 4.8 | 2.2 | 12.3 | |
| 79 | Richie Lucas | 1961 | 23 | BUF | 8 | 2 | 20 | 50 | 40.0 | 282 | 2 | 4.0 | 4 | 8.0 | 45 | 5.6 | 2.4 | 14.1 | 35.3 | 38.9 | ||||||
| 80 | Richie Lucas | 1960 | 22 | BUF | 14 | 2 | 23 | 49 | 46.9 | 314 | 2 | 4.1 | 3 | 6.1 | 36 | 6.4 | 4.1 | 13.7 | 22.4 | 56.0 | ||||||
| 81 | Frank Reich | 1992 | 31 | BUF | 16 | 0 | 24 | 47 | 51.1 | 221 | 0 | 0.0 | 2 | 4.3 | 21 | 4.7 | 2.8 | 9.2 | 13.8 | 46.5 | 9 | 76 | 2.6 | 1.0 | 16.1 | |
| 82 | Dennis Shaw | 1973 | 26 | BUF | 4 | 0 | 22 | 46 | 47.8 | 300 | 0 | 0.0 | 4 | 8.7 | 40 | 6.5 | 2.6 | 13.6 | 75.0 | 32.9 | 11 | 75 | 3.9 | 0.8 | 19.3 | |
| 83 | Bill Munson | 1978 | 37 | BUF | 4 | 0 | 24 | 43 | 55.8 | 328 | 4 | 9.3 | 2 | 4.7 | 43 | 7.6 | 6.5 | 13.7 | 82.0 | 92.0 | 0 | 0 | 7.6 | 6.5 | 0.0 | |
| 84 | Frank Reich | 1991 | 30 | BUF | 16 | 1 | 27 | 41 | 65.9 | 305 | 6 | 14.6 | 2 | 4.9 | 29 | 7.4 | 6.7 | 11.3 | 19.1 | 107.2 | 4 | 42 | 5.8 | 5.2 | 8.9 | |
| 85 | Brian McClure | 1987 | 24 | BUF | 1 | 1 | 20 | 38 | 52.6 | 181 | 0 | 0.0 | 3 | 7.9 | 30 | 4.8 | 1.2 | 9.1 | 181.0 | 32.9 | 2 | 17 | 4.1 | 0.7 | 5.0 | |
| 86 | James Harris | 1969 | 22 | BUF | 4 | 1 | 15 | 36 | 41.7 | 270 | 1 | 2.8 | 1 | 2.8 | 55 | 7.5 | 6.5 | 18.0 | 67.5 | 65.7 | 9 | 70 | 4.4 | 3.7 | 20.0 | |
| 87 | Rob Johnson | 1999 | 26 | BUF | 2 | 1 | 25 | 34 | 73.5 | 298 | 2 | 5.9 | 0 | 0.0 | 42 | 8.8 | 9.4 | 11.9 | 149.0 | 119.5 | 1 | 9 | 8.3 | 8.8 | 2.9 | |
| 88 | Travis Brown | 2001 | 24 | BUF | 1 | 0 | 15 | 33 | 45.5 | 201 | 1 | 3.0 | 2 | 6.1 | 34 | 6.1 | 3.7 | 13.4 | 201.0 | 50.2 | 1 | 2 | 5.9 | 3.5 | 2.9 | |
| 89 | Gary Marangi | 1975 | 23 | BUF | 5 | 0 | 13 | 33 | 39.4 | 235 | 3 | 9.1 | 2 | 6.1 | 64 | 7.1 | 5.3 | 18.1 | 47.0 | 69.6 | 2 | 15 | 6.3 | 4.6 | 5.7 | |
| Rk | Year | Age | Tm | Pos | G | GS | Cmp | Att | Yds | TD | Int | Lng | Sk | Yds | ||||||||||||
| 90 | Mike Taliaferro | 1972 | 31 | BUF | 5 | 0 | 16 | 33 | 48.5 | 176 | 1 | 3.0 | 4 | 12.1 | 24 | 5.3 | 0.2 | 11.0 | 35.2 | 35.2 | 6 | 48 | 3.3 | -1.1 | 15.4 | |
| 91 | Willie Totten | 1987 | 25 | BUF | 2 | 1 | 13 | 33 | 39.4 | 155 | 2 | 6.1 | 2 | 6.1 | 37 | 4.7 | 2.6 | 11.9 | 77.5 | 49.4 | 5 | 62 | 2.4 | 0.6 | 13.2 | |
| 92 | Billy Joe Hobert | 1997 | 26 | BUF | 2 | 0 | 17 | 30 | 56.7 | 133 | 0 | 0.0 | 2 | 6.7 | 20 | 4.4 | 1.4 | 7.8 | 66.5 | 40.0 | 2 | 7 | 3.9 | 1.1 | 6.3 | |
| 93 | Todd Collins | 1995 | 24 | BUF | 7 | 1 | 14 | 29 | 48.3 | 112 | 0 | 0.0 | 1 | 3.4 | 18 | 3.9 | 2.3 | 8.0 | 16.0 | 44.0 | 6 | 43 | 2.0 | 0.7 | 17.1 | |
| 94 | Dan Darragh | 1970 | 24 | BUF | 3 | 2 | 11 | 29 | 37.9 | 71 | 0 | 0.0 | 2 | 6.9 | 19 | 2.4 | -0.7 | 6.5 | 23.7 | 17.5 | 5 | 36 | 1.0 | -1.6 | 14.7 | |
| 95 | Frank Reich | 1993 | 32 | BUF | 15 | 0 | 16 | 26 | 61.5 | 153 | 2 | 7.7 | 0 | 0.0 | 30 | 5.9 | 6.7 | 9.6 | 10.2 | 103.5 | 6 | 47 | 3.3 | 3.9 | 18.8 | |
| 96 | Bob Brodhead | 1960 | 24 | BUF | 4 | 1 | 7 | 25 | 28.0 | 75 | 0 | 0.0 | 3 | 12.0 | 18 | 3.0 | -2.4 | 10.7 | 18.8 | 0.0 | ||||||
| 97 | Dan Manucci | 1987 | 30 | BUF | 3 | 1 | 7 | 21 | 33.3 | 68 | 0 | 0.0 | 2 | 9.5 | 15 | 3.2 | -1.0 | 9.7 | 22.7 | 3.8 | 3 | 27 | 1.7 | -2.0 | 12.5 | |
| 98 | Frank Reich | 1986 | 25 | BUF | 3 | 0 | 9 | 19 | 47.4 | 104 | 0 | 0.0 | 2 | 10.5 | 37 | 5.5 | 0.7 | 11.6 | 34.7 | 24.8 | 2 | 4 | 4.8 | 0.5 | 9.5 | |
| 99 | Travis Brown | 2003 | 26 | BUF | 2 | 0 | 14 | 18 | 77.8 | 160 | 0 | 0.0 | 1 | 5.6 | 28 | 8.9 | 6.4 | 11.4 | 80.0 | 80.6 | 1 | 7 | 8.1 | 5.7 | 5.3 | |
| 100 | Gary Marangi | 1974 | 22 | BUF | 3 | 0 | 9 | 18 | 50.0 | 140 | 2 | 11.1 | 3 | 16.7 | 44 | 7.8 | 1.4 | 15.6 | 46.7 | 73.6 | 1 | 1 | 7.3 | 1.3 | 5.3 | |
| 101 | Alex Van Pelt | 1995 | 25 | BUF | 1 | 0 | 10 | 18 | 55.6 | 106 | 2 | 11.1 | 0 | 0.0 | 19 | 5.9 | 7.0 | 10.6 | 106.0 | 110.0 | 0 | 0 | 5.9 | 7.0 | 0.0 | |
| 102 | Gale Gilbert | 1990 | 29 | BUF | 1 | 0 | 8 | 15 | 53.3 | 106 | 2 | 13.3 | 2 | 13.3 | 23 | 7.1 | 2.4 | 13.3 | 106.0 | 76.0 | 1 | 9 | 6.1 | 1.7 | 6.3 | |
| 103 | Leo Hart | 1972 | 23 | BUF | 2 | 1 | 6 | 15 | 40.0 | 53 | 0 | 0.0 | 3 | 20.0 | 13 | 3.5 | -5.5 | 8.8 | 26.5 | 10.6 | 4 | 32 | 1.1 | -6.0 | 21.1 | |
| 104 | Dave Mays | 1978 | 29 | BUF | 1 | 0 | 4 | 15 | 26.7 | 39 | 1 | 6.7 | 0 | 0.0 | 19 | 2.6 | 3.3 | 9.8 | 39.0 | 61.8 | 1 | 11 |