| Single-season | Passing | Rushing | Receiving | Returns | Kicking | Scoring | |
| Career | Passing | Rushing | Receiving | Returns | Kicking | Scoring | Defense |
| Rk | Year | Age | Tm | Pos | G | GS | Rec | Yds | TD | Lng | Fmb | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Eric Moulds | 2002* | 29 | BUF | WR | 16 | 15 | 100 | 1292 | 12.9 | 10 | 70 | 6.3 | 80.8 | 1 |
| 2 | Eric Moulds | 2000* | 27 | BUF | WR | 16 | 16 | 94 | 1326 | 14.1 | 5 | 52 | 5.9 | 82.9 | 1 |
| 3 | Peerless Price | 2002 | 26 | BUF | WR | 16 | 16 | 94 | 1252 | 13.3 | 9 | 73 | 5.9 | 78.3 | 2 |
| 4 | Andre Reed | 1994* | 30 | BUF | WR | 16 | 16 | 90 | 1303 | 14.5 | 8 | 83 | 5.6 | 81.4 | 3 |
| 5 | Eric Moulds | 2004 | 31 | BUF | WR | 16 | 16 | 88 | 1043 | 11.9 | 5 | 49 | 5.5 | 65.2 | 1 |
| 6 | Andre Reed | 1989* | 25 | BUF | WR | 16 | 16 | 88 | 1312 | 14.9 | 9 | 78 | 5.5 | 82.0 | 4 |
| 7 | Lee Evans | 2006 | 25 | BUF | WR | 16 | 15 | 82 | 1292 | 15.8 | 8 | 83 | 5.1 | 80.8 | 1 |
| 8 | Eric Moulds | 2005 | 32 | BUF | WR | 15 | 15 | 81 | 816 | 10.1 | 4 | 55 | 5.4 | 54.4 | 0 |
| 9 | Andre Reed | 1991* | 27 | BUF | WR | 16 | 16 | 81 | 1113 | 13.7 | 10 | 55 | 5.1 | 69.6 | 1 |
| 10 | Larry Centers | 2001* | 33 | BUF | FB | 16 | 13 | 80 | 620 | 7.8 | 2 | 26 | 5.0 | 38.8 | 2 |
| 11 | Andre Reed | 1990* | 26 | BUF | WR | 16 | 16 | 71 | 945 | 13.3 | 8 | 56 | 4.4 | 59.1 | 1 |
| 12 | Andre Reed | 1988* | 24 | BUF | WR | 15 | 14 | 71 | 968 | 13.6 | 6 | 65 | 4.7 | 64.5 | 1 |
| 13 | Frank Lewis | 1981* | 34 | BUF | WR | 16 | 16 | 70 | 1244 | 17.8 | 4 | 33 | 4.4 | 77.8 | 1 |
| 14 | Byron Franklin | 1984 | 26 | BUF | WR | 16 | 16 | 69 | 862 | 12.5 | 4 | 64 | 4.3 | 53.9 | 4 |
| 15 | Bill Miller | 1963 | 23 | BUF | SE | 14 | 0 | 69 | 860 | 12.5 | 3 | 36 | 4.9 | 61.4 | 0 |
| 16 | Pete Metzelaars | 1993 | 33 | BUF | TE | 16 | 16 | 68 | 609 | 9.0 | 4 | 51 | 4.3 | 38.1 | 1 |
| 17 | Eric Moulds | 2001 | 28 | BUF | WR | 16 | 16 | 67 | 904 | 13.5 | 5 | 80 | 4.2 | 56.5 | 1 |
| 18 | Eric Moulds | 1998* | 25 | BUF | WR | 16 | 15 | 67 | 1368 | 20.4 | 9 | 84 | 4.2 | 85.5 | 0 |
| 19 | Andre Reed | 1996 | 32 | BUF | WR | 16 | 16 | 66 | 1036 | 15.7 | 6 | 67 | 4.1 | 64.8 | 1 |
| 20 | Eric Moulds | 1999 | 26 | BUF | WR | 14 | 14 | 65 | 994 | 15.3 | 7 | 54 | 4.6 | 71.0 | 1 |
| 21 | Andre Reed | 1992* | 28 | BUF | WR | 16 | 16 | 65 | 913 | 14.0 | 3 | 51 | 4.1 | 57.1 | 4 |
| 22 | Eric Moulds | 2003 | 30 | BUF | WR | 13 | 13 | 64 | 780 | 12.2 | 1 | 49 | 4.9 | 60.0 | 0 |
| 23 | Andre Reed | 1998 | 34 | BUF | WR | 15 | 13 | 63 | 795 | 12.6 | 5 | 67 | 4.2 | 53.0 | 0 |
| 24 | Thurman Thomas | 1991*+ | 25 | BUF | RB | 15 | 15 | 62 | 631 | 10.2 | 5 | 50 | 4.1 | 42.1 | 5 |
| 25 | Bob Chandler | 1976 | 27 | BUF | WR | 14 | 14 | 61 | 824 | 13.5 | 10 | 58 | 4.4 | 58.9 | 3 |
| 26 | Bill Brooks | 1993 | 29 | BUF | WR | 16 | 13 | 60 | 714 | 11.9 | 5 | 32 | 3.8 | 44.6 | 0 |
| 27 | Bob Chandler | 1977 | 28 | BUF | WR | 14 | 0 | 60 | 745 | 12.4 | 4 | 31 | 4.3 | 53.2 | 0 |
| 28 | Quinn Early | 1997 | 32 | BUF | WR | 16 | 16 | 60 | 853 | 14.2 | 5 | 45 | 3.8 | 53.3 | 0 |
| 29 | Andre Reed | 1997 | 33 | BUF | WR | 15 | 15 | 60 | 880 | 14.7 | 5 | 77 | 4.0 | 58.7 | 1 |
| Rk | Year | Age | Tm | Pos | G | GS | Rec | Yds | TD | Lng | Fmb | ||||
| 30 | Thurman Thomas | 1989* | 23 | BUF | RB | 16 | 16 | 60 | 669 | 11.2 | 6 | 74 | 3.8 | 41.8 | 7 |
| 31 | Greg Bell | 1985 | 23 | BUF | FB/rb | 16 | 15 | 58 | 576 | 9.9 | 1 | 49 | 3.6 | 36.0 | 8 |
| 32 | Josh Reed | 2003 | 23 | BUF | WR | 16 | 16 | 58 | 588 | 10.1 | 2 | 26 | 3.6 | 36.8 | 1 |
| 33 | Thurman Thomas | 1992* | 26 | BUF | RB | 16 | 16 | 58 | 626 | 10.8 | 3 | 43 | 3.6 | 39.1 | 6 |
| 34 | Marlin Briscoe | 1970* | 25 | BUF | WR | 14 | 0 | 57 | 1036 | 18.2 | 8 | 48 | 4.1 | 74.0 | 3 |
| 35 | Jerry Butler | 1980* | 23 | BUF | WR | 16 | 16 | 57 | 832 | 14.6 | 6 | 69 | 3.6 | 52.0 | 0 |
| 36 | Joe Cribbs | 1983* | 25 | BUF | RB | 16 | 16 | 57 | 524 | 9.2 | 7 | 33 | 3.6 | 32.8 | 6 |
| 37 | James Lofton | 1991* | 35 | BUF | WR | 15 | 15 | 57 | 1072 | 18.8 | 8 | 77 | 3.8 | 71.5 | 2 |
| 38 | Andre Reed | 1987 | 23 | BUF | WR | 12 | 12 | 57 | 752 | 13.2 | 5 | 40 | 4.8 | 62.7 | 0 |
| 39 | Chris Burkett | 1987 | 25 | BUF | WR | 12 | 12 | 56 | 765 | 13.7 | 4 | 47 | 4.7 | 63.8 | 1 |
| 40 | Ronnie Harmon | 1987 | 23 | BUF | RB | 12 | 10 | 56 | 477 | 8.5 | 2 | 42 | 4.7 | 39.8 | 2 |
| 41 | Bobby Shaw | 2003 | 28 | BUF | wr | 16 | 7 | 56 | 732 | 13.1 | 4 | 54 | 3.5 | 45.8 | 1 |
| 42 | Jerry Butler | 1981 | 24 | BUF | WR | 16 | 16 | 55 | 842 | 15.3 | 8 | 67 | 3.4 | 52.6 | 2 |
| 43 | Bob Chandler | 1975 | 26 | BUF | WR | 14 | 13 | 55 | 746 | 13.6 | 6 | 35 | 3.9 | 53.3 | 0 |
| 44 | Lee Evans | 2007 | 26 | BUF | WR | 16 | 16 | 55 | 849 | 15.4 | 5 | 85 | 3.4 | 53.1 | 0 |
| 45 | Peerless Price | 2001 | 25 | BUF | WR | 16 | 16 | 55 | 895 | 16.3 | 7 | 70 | 3.4 | 55.9 | 2 |
| 46 | Frank Lewis | 1979 | 32 | BUF | WR | 15 | 15 | 54 | 1082 | 20.0 | 2 | 55 | 3.6 | 72.1 | 1 |
| 47 | Bill Brooks | 1995 | 31 | BUF | WR | 15 | 10 | 53 | 763 | 14.4 | 11 | 51 | 3.5 | 50.9 | 0 |
| 48 | Elbert Dubenion | 1963 | 30 | BUF | FL | 14 | 0 | 53 | 959 | 18.1 | 4 | 89 | 3.8 | 68.5 | 2 |
| 49 | Andre Reed | 1986 | 22 | BUF | WR | 15 | 15 | 53 | 739 | 13.9 | 7 | 55 | 3.5 | 49.3 | 2 |
| 50 | Jay Riemersma | 2001 | 28 | BUF | TE | 16 | 15 | 53 | 590 | 11.1 | 3 | 36 | 3.3 | 36.9 | 0 |
| 51 | Joe Cribbs | 1980* | 22 | BUF | RB | 16 | 16 | 52 | 415 | 8.0 | 1 | 21 | 3.3 | 25.9 | 16 |
| 52 | J.D. Hill | 1972* | 24 | BUF | WR | 14 | 0 | 52 | 754 | 14.5 | 5 | 58 | 3.7 | 53.9 | 1 |
| 53 | Peerless Price | 2000 | 24 | BUF | WR | 16 | 16 | 52 | 762 | 14.7 | 3 | 42 | 3.3 | 47.6 | 4 |
| 54 | Andre Reed | 1999 | 35 | BUF | WR | 16 | 16 | 52 | 536 | 10.3 | 1 | 30 | 3.3 | 33.5 | 0 |
| 55 | Andre Reed | 1993* | 29 | BUF | WR | 15 | 15 | 52 | 854 | 16.4 | 6 | 65 | 3.5 | 56.9 | 3 |
| 56 | James Lofton | 1992 | 36 | BUF | WR | 16 | 15 | 51 | 786 | 15.4 | 6 | 50 | 3.2 | 49.1 | 0 |
| 57 | Josh Reed | 2007 | 27 | BUF | WR | 15 | 9 | 51 | 578 | 11.3 | 0 | 30 | 3.4 | 38.5 | 0 |
| 58 | Glenn Bass | 1961 | 22 | BUF | SE | 14 | 0 | 50 | 765 | 15.3 | 3 | 76 | 3.6 | 54.6 | 2 |
| 59 | Elbert Dubenion | 1966 | 33 | BUF | FL | 14 | 0 | 50 | 747 | 14.9 | 2 | 44 | 3.6 | 53.4 | 0 |
| Rk | Year | Age | Tm | Pos | G | GS | Rec | Yds | TD | Lng | Fmb | ||||
| 60 | Quinn Early | 1996 | 31 | BUF | WR | 16 | 13 | 50 | 798 | 16.0 | 4 | 95 | 3.1 | 49.9 | 0 |
| 61 | Thurman Thomas | 1994 | 28 | BUF | RB | 15 | 15 | 50 | 349 | 7.0 | 2 | 28 | 3.3 | 23.3 | 1 |
| 62 | Lonnie Johnson | 1995 | 24 | BUF | TE | 16 | 16 | 49 | 504 | 10.3 | 1 | 52 | 3.1 | 31.5 | 0 |
| 63 | Pete Metzelaars | 1986 | 26 | BUF | TE | 16 | 16 | 49 | 485 | 9.9 | 3 | 44 | 3.1 | 30.3 | 2 |
| 64 | Pete Metzelaars | 1994 | 34 | BUF | TE | 16 | 16 | 49 | 428 | 8.7 | 5 | 35 | 3.1 | 26.8 | 0 |
| 65 | Peerless Price | 2006 | 30 | BUF | WR | 16 | 15 | 49 | 402 | 8.2 | 3 | 25 | 3.1 | 25.1 | 1 |
| 66 | Robb Riddick | 1986 | 29 | BUF | RB | 15 | 8 | 49 | 468 | 9.6 | 1 | 31 | 3.3 | 31.2 | 8 |
| 67 | Thurman Thomas | 1990*+ | 24 | BUF | RB | 16 | 16 | 49 | 532 | 10.9 | 2 | 63 | 3.1 | 33.3 | 6 |
| 68 | Jerry Butler | 1979 | 22 | BUF | WR | 13 | 13 | 48 | 834 | 17.4 | 4 | 75 | 3.7 | 64.2 | 1 |
| 69 | Lee Evans | 2004 | 23 | BUF | WR | 16 | 11 | 48 | 843 | 17.6 | 9 | 69 | 3.0 | 52.7 | 1 |
| 70 | Lee Evans | 2005 | 24 | BUF | WR | 16 | 15 | 48 | 743 | 15.5 | 7 | 65 | 3.0 | 46.4 | 0 |
| 71 | Andre Reed | 1985 | 21 | BUF | WR | 16 | 15 | 48 | 637 | 13.3 | 4 | 32 | 3.0 | 39.8 | 2 |
| 72 | Thurman Thomas | 1993* | 27 | BUF | RB | 16 | 16 | 48 | 387 | 8.1 | 0 | 37 | 3.0 | 24.2 | 6 |
| 73 | Lonnie Johnson | 1996 | 25 | BUF | TE | 16 | 15 | 46 | 457 | 9.9 | 0 | 33 | 2.9 | 28.6 | 1 |
| 74 | Tom Rychlec | 1960 | 26 | BUF | TE | 14 | 0 | 45 | 590 | 13.1 | 0 | 36 | 3.2 | 42.1 | 0 |
| 75 | Marlin Briscoe | 1971 | 26 | BUF | WR | 14 | 0 | 44 | 603 | 13.7 | 5 | 75 | 3.1 | 43.1 | 0 |
| 76 | Bob Chandler | 1978 | 29 | BUF | WR | 16 | 0 | 44 | 581 | 13.2 | 5 | 44 | 2.8 | 36.3 | 1 |
| 77 | Keith McKeller | 1991 | 27 | BUF | TE | 16 | 14 | 44 | 434 | 9.9 | 3 | 29 | 2.8 | 27.1 | 0 |
| 78 | Glenn Bass | 1964 | 25 | BUF | WR | 14 | 0 | 43 | 897 | 20.9 | 7 | 94 | 3.1 | 64.1 | 1 |
| 79 | Jim Braxton | 1977 | 28 | BUF | FB | 14 | 14 | 43 | 461 | 10.7 | 1 | 27 | 3.1 | 32.9 | 7 |
| 80 | Larry Centers | 2002 | 34 | BUF | FB | 16 | 7 | 43 | 388 | 9.0 | 0 | 25 | 2.7 | 24.3 | 0 |
| 81 | Travis Henry | 2002* | 24 | BUF | RB | 16 | 16 | 43 | 309 | 7.2 | 1 | 26 | 2.7 | 19.3 | 11 |
| 82 | Jeremy McDaniel | 2000 | 24 | BUF | wr | 16 | 6 | 43 | 697 | 16.2 | 2 | 74 | 2.7 | 43.6 | 0 |
| 83 | Bill Brooks | 1994 | 30 | BUF | WR | 16 | 9 | 42 | 482 | 11.5 | 2 | 32 | 2.6 | 30.1 | 1 |
| 84 | Russell Copeland | 1995 | 24 | BUF | WR | 16 | 15 | 42 | 646 | 15.4 | 1 | 77 | 2.6 | 40.4 | 1 |
| 85 | Elbert Dubenion | 1960 | 27 | BUF | FL | 14 | 0 | 42 | 752 | 17.9 | 7 | 64 | 3.0 | 53.7 | 3 |
| 86 | Elbert Dubenion | 1964* | 31 | BUF | FL | 14 | 0 | 42 | 1139 | 27.1 | 10 | 72 | 3.0 | 81.4 | 0 |
| 87 | Haven Moses | 1968 | 22 | BUF | SE | 14 | 0 | 42 | 633 | 15.1 | 2 | 55 | 3.0 | 45.2 | 0 |
| 88 | Jerry Butler | 1985 | 28 | BUF | WR | 16 | 13 | 41 | 770 | 18.8 | 2 | 60 | 2.6 | 48.1 | 0 |
| 89 | Reuben Gant | 1977 | 25 | BUF | 14 | 1 | 41 | 646 | 15.8 | 2 | 39 | 2.9 | 46.1 | 0 | |
| Rk | Year | Age | Tm | Pos | G | GS | Rec | Yds | TD | Lng | Fmb | ||||
| 90 | Lonnie Johnson | 1997 | 26 | BUF | TE | 16 | 16 | 41 | 340 | 8.3 | 2 | 62 | 2.6 | 21.3 | 2 |
| 91 | Frank Lewis | 1978 | 31 | BUF | WR | 15 | 15 | 41 | 735 | 17.9 | 7 | 92 | 2.7 | 49.0 | 0 |
| 92 | Keith Lincoln | 1967* | 28 | BUF | HB | 14 | 14 | 41 | 558 | 13.6 | 5 | 60 | 2.9 | 39.9 | 3 |
| 93 | Don Beebe | 1994 | 30 | BUF | WR | 13 | 11 | 40 | 527 | 13.2 | 4 | 72 | 3.1 | 40.5 | 3 |
| 94 | Joe Cribbs | 1981* | 23 | BUF | RB | 15 | 15 | 40 | 603 | 15.1 | 7 | 65 | 2.7 | 40.2 | 12 |
| 95 | Frank Lewis | 1980 | 33 | BUF | WR | 15 | 14 | 40 | 648 | 16.2 | 6 | 31 | 2.7 | 43.2 | 0 |
| 96 | Curtis Brown | 1979 | 25 | BUF | FB | 15 | 15 | 39 | 401 | 10.3 | 3 | 84 | 2.6 | 26.7 | 10 |
| 97 | Paul Costa | 1967 | 26 | BUF | TE | 14 | 14 | 39 | 726 | 18.6 | 2 | 63 | 2.8 | 51.9 | 2 |
| 98 | Haven Moses | 1970 | 24 | BUF | WR | 14 | 0 | 39 | 726 | 18.6 | 2 | 45 | 2.8 | 51.9 | 0 |
| 99 | Haven Moses | 1969* | 23 | BUF | SE | 14 | 0 | 39 | 752 | 19.3 | 5 | 55 | 2.8 | 53.7 | 0 |
| 100 | Ronnie Harmon | 1988 | 24 | BUF | 16 | 1 | 37 | 427 | 11.5 | 3 | 36 | 2.3 | 26.7 | 2 | |
| 101 | Trumaine Johnson | 1988 | 28 | BUF | WR | 16 | 10 | 37 | 514 | 13.9 | 0 | 49 | 2.3 | 32.1 | 1 |
| 102 | Sammy Morris | 2000 | 23 | BUF | RB | 12 | 8 | 37 | 268 | 7.2 | 1 | 24 | 3.1 | 22.3 | 2 |
| 103 | Eason Ramson | 1985 | 29 | BUF | TE | 16 | 12 | 37 | 369 | 10.0 | 1 | 43 | 2.3 | 23.1 | 1 |
| 104 | Josh Reed | 2002 | 22 | BUF | 16 | 2 | 37 | 509 | 13.8 | 2 | 42 | 2.3 | 31.8 | 1 | |
| 105 | Jay Riemersma | 1999 | 26 | BUF | TE | 14 | 11 | 37 | 496 | 13.4 | 4 | 38 | 2.6 | 35.4 | 0 |
| 106 | Jerry Butler | 1983 | 26 | BUF | WR | 9 | 9 | 36 | 385 | 10.7 | 3 | 25 | 4.0 | 42.8 | 1 |
| 107 | J.D. Hill | 1975 | 27 | BUF | WR | 14 | 0 | 36 | 667 | 18.5 | 7 | 77 | 2.6 | 47.6 | 0 |
| 108 | Tony Hunter | 1983 | 23 | BUF | 13 | 3 | 36 | 402 | 11.2 | 3 | 40 | 2.8 | 30.9 | 1 | |
| 109 | Frank Lewis | 1983 | 36 | BUF | WR | 11 | 11 | 36 | 486 | 13.5 | 3 | 27 | 3.3 | 44.2 | 0 |
| 110 | Wayne Patrick | 1971 | 25 | BUF | FB | 14 | 0 | 36 | 327 | 9.1 | 0 | 62 | 2.6 | 23.4 | 5 |
| 111 | Ahmad Rashad | 1974 | 25 | BUF | WR | 14 | 0 | 36 | 433 | 12.0 | 4 | 29 | 2.6 | 30.9 | 0 |
| 112 | Bill Enyart | 1970 | 23 | BUF | 14 | 0 | 35 | 235 | 6.7 | 1 | 37 | 2.5 | 16.8 | 2 | |
| 113 | James Lofton | 1990 | 34 | BUF | WR | 16 | 14 | 35 | 712 | 20.3 | 4 | 71 | 2.2 | 44.5 | 0 |
| 114 | Roscoe Parrish | 2007 | 25 | BUF | RET | 16 | 3 | 35 | 352 | 10.1 | 1 | 47 | 2.2 | 22.0 | 1 |
| 115 | Wayne Patrick | 1969 | 23 | BUF | FB | 14 | 0 | 35 | 229 | 6.5 | 0 | 19 | 2.5 | 16.4 | 6 |
| 116 | Ernie Warlick | 1962* | 30 | BUF | TE | 14 | 0 | 35 | 482 | 13.8 | 2 | 25 | 2.5 | 34.4 | 1 |
| 117 | Greg Bell | 1984* | 22 | BUF | RB | 16 | 15 | 34 | 277 | 8.1 | 1 | 37 | 2.1 | 17.3 | 5 |
| 118 | Chris Burkett | 1986 | 24 | BUF | WR | 14 | 10 | 34 | 778 | 22.9 | 4 | 84 | 2.4 | 55.6 | 1 |
| 119 | Bobby Burnett | 1966* | 23 | BUF | HB | 14 | 0 | 34 | 419 | 12.3 | 4 | 48 | 2.4 | 29.9 | 3 |
| Rk | Year | Age | Tm | Pos | G | GS | Rec | Yds | TD | Lng | Fmb | ||||
| 120 | Mark Campbell | 2003 | 28 | BUF | TE | 16 | 11 | 34 | 339 | 10.0 | 1 | 31 | 2.1 | 21.2 | 0 |
| 121 | Reuben Gant | 1978 | 26 | BUF | TE | 16 | 16 | 34 | 408 | 12.0 | 5 | 25 | 2.1 | 25.5 | 1 |
| 122 | Keith McKeller | 1990 | 26 | BUF | TE | 16 | 14 | 34 | 464 | 13.6 | 5 | 43 | 2.1 | 29.0 | 1 |
| 123 | Booker Moore | 1983 | 24 | BUF | FB | 15 | 11 | 34 | 199 | 5.9 | 1 | 21 | 2.3 | 13.3 | 1 |
| 124 | Josh Reed | 2006 | 26 | BUF | 13 | 1 | 34 | 410 | 12.1 | 2 | 52 | 2.6 | 31.5 | 0 | |
| 125 | Don Beebe | 1992 | 28 | BUF | WR | 12 | 8 | 33 | 554 | 16.8 | 2 | 65 | 2.8 | 46.2 | 1 |
| 126 | Mark Brammer | 1981 | 23 | BUF | TE | 16 | 16 | 33 | 365 | 11.1 | 2 | 24 | 2.1 | 22.8 | 3 |
| 127 | Bob Chandler | 1972 | 23 | BUF | WR | 14 | 0 | 33 | 528 | 16.0 | 5 | 43 | 2.4 | 37.7 | 1 |
| 128 | Elbert Dubenion | 1962 | 29 | BUF | FL | 14 | 0 | 33 | 571 | 17.3 | 5 | 75 | 2.4 | 40.8 | 1 |
| 129 | Tony Hunter | 1984 | 24 | BUF | TE | 11 | 9 | 33 | 331 | 10.0 | 2 | 30 | 3.0 | 30.1 | 1 |
| 130 | Billy Masters | 1969 | 25 | BUF | TE | 14 | 0 | 33 | 387 | 11.7 | 1 | 31 | 2.4 | 27.6 | 1 |
| 131 | Pete Metzelaars | 1988 | 28 | BUF | TE | 16 | 16 | 33 | 438 | 13.3 | 1 | 35 | 2.1 | 27.4 | 0 |
| 132 | Booker Moore | 1984 | 25 | BUF | FB | 15 | 15 | 33 | 172 | 5.2 | 0 | 14 | 2.2 | 11.5 | 4 |
| 133 | Lou Piccone | 1979 | 30 | BUF | 16 | 4 | 33 | 556 | 16.8 | 2 | 49 | 2.1 | 34.8 | 1 | |
| 134 | Tom Rychlec | 1961 | 27 | BUF | TE | 14 | 0 | 33 | 405 | 12.3 | 2 | 27 | 2.4 | 28.9 | 0 |
| 135 | Glenn Bass | 1962 | 23 | BUF | SE | 14 | 0 | 32 | 555 | 17.3 | 4 | 76 | 2.3 | 39.6 | 0 |
| 136 | Don Beebe | 1991 | 27 | BUF | WR | 11 | 7 | 32 | 414 | 12.9 | 6 | 34 | 2.9 | 37.6 | 3 |
| 137 | Marlin Briscoe | 1969 | 24 | BUF | FL | 13 | 0 | 32 | 532 | 16.6 | 5 | 50 | 2.5 | 40.9 | 1 |
| 138 | Shawn Bryson | 2000 | 24 | BUF | rb | 16 | 7 | 32 | 271 | 8.5 | 2 | 32 | 2.0 | 16.9 | 1 |
| 139 | J.D. Hill | 1974 | 26 | BUF | WR | 14 | 0 | 32 | 572 | 17.9 | 6 | 55 | 2.3 | 40.9 | 0 |
| 140 | Josh Reed | 2005 | 25 | BUF | wr | 16 | 6 | 32 | 449 | 14.0 | 2 | 51 | 2.0 | 28.1 | 0 |
| 141 | Jay Riemersma | 2002 | 29 | BUF | TE | 16 | 15 | 32 | 350 | 10.9 | 0 | 29 | 2.0 | 21.9 | 0 |
| 142 | Don Beebe | 1993 | 29 | BUF | WR | 14 | 14 | 31 | 504 | 16.3 | 3 | 65 | 2.2 | 36.0 | 1 |
| 143 | Bobby Crockett | 1966 | 23 | BUF | SE | 14 | 12 | 31 | 533 | 17.2 | 3 | 53 | 2.2 | 38.1 | 0 |
| 144 | Elbert Dubenion | 1961 | 28 | BUF | FL | 14 | 0 | 31 | 461 | 14.9 | 6 | 61 | 2.2 | 32.9 | 1 |
| 145 | Peerless Price | 1999 | 23 | BUF | 16 | 4 | 31 | 393 | 12.7 | 3 | 45 | 1.9 | 24.6 | 0 | |
| 146 | Jay Riemersma | 2000 | 27 | BUF | TE | 12 | 12 | 31 | 372 | 12.0 | 5 | 35 | 2.6 | 31.0 | 1 |
| 147 | Bo Roberson | 1965* | 30 | BUF | FL | 8 | 0 | 31 | 483 | 15.6 | 3 | 74 | 3.9 | 60.4 | 0 |
| 148 | Kevin Williams | 1999 | 28 | BUF | RET | 16 | 0 | 31 | 381 | 12.3 | 0 | 35 | 1.9 | 23.8 | 0 |
| 149 | Bob Chandler | 1973 | 24 | BUF | WR | 14 | 0 | 30 | 427 | 14.2 | 3 | 37 | 2.1 | 30.5 | 2 |
| Rk | Year | Age | Tm | Pos | G | GS | Rec | Yds | TD | Lng | Fmb | ||||
| 150 | Preston Dennard | 1984 | 29 | BUF | WR | 16 | 13 | 30 | 417 | 13.9 | 7 | 68 | 1.9 | 26.1 | 1 |
| 151 | Byron Franklin | 1983 | 25 | BUF | wr | 15 | 5 | 30 | 452 | 15.1 | 4 | 43 | 2.0 | 30.1 | 0 |
| 152 | Cookie Gilchrist | 1964*+ | 29 | BUF | FB | 14 | 0 | 30 | 345 | 11.5 | 0 | 37 | 2.1 | 24.6 | 6 |
| 153 | Pete Metzelaars | 1992 | 32 | BUF | te | 16 | 7 | 30 | 298 | 9.9 | 6 | 53 | 1.9 | 18.6 | 0 |
| 154 | Robb Riddick | 1988 | 31 | BUF | 15 | 0 | 30 | 282 | 9.4 | 1 | 26 | 2.0 | 18.8 | 3 | |
| 155 | O.J. Simpson | 1969* | 22 | BUF | HB | 13 | 0 | 30 | 343 | 11.4 | 3 | 55 | 2.3 | 26.4 | 6 |
| 156 | Thurman Thomas | 1997 | 31 | BUF | RB | 16 | 16 | 30 | 208 | 6.9 | 0 | 30 | 1.9 | 13.0 | 2 |
| 157 | Wray Carlton | 1960 | 23 | BUF | FB | 14 | 0 | 29 | 477 | 16.4 | 4 | 70 | 2.1 | 34.1 | 7 |
| 158 | Ronnie Harmon | 1989 | 25 | BUF | RET | 15 | 2 | 29 | 363 | 12.5 | 4 | 42 | 1.9 | 24.2 | 2 |
| 159 | J.D. Hill | 1973 | 25 | BUF | WR | 14 | 0 | 29 | 422 | 14.6 | 0 | 42 | 2.1 | 30.1 | 2 |
| 160 | Jonathan Linton | 1999 | 25 | BUF | RB | 16 | 2 | 29 | 228 | 7.9 | 1 | 28 | 1.8 | 14.3 | 4 |
| 161 | Eric Moulds | 1997 |