| Offensive Starters | | | | | |
QB | Matt Schaub | 30 | 7 | 10 | 178 for 292, 2,479 yards, 15 td, 6 int, & 15 rushes for 9 yards and 2 td | |
RB | Arian Foster* | 25 | 2 | 13 | 278 rushes for 1,224 yards, 10 td, & 53 catches for 617 yards and 2 td | |
WR | Jacoby Jones | 27 | 4 | 10 | 31 catches for 512 yards, 2 td, & 4 rushes for 17 yards and 0 td | |
WR | Kevin Walter | 30 | 8 | 14 | 39 catches for 474 yards, 3 td | |
TE | Owen Daniels | 29 | 5 | 15 | 54 catches for 677 yards, 3 td | |
TE | Joel Dreessen | 29 | 6 | 10 | 28 catches for 353 yards, 6 td | |
LT | Duane Brown | 26 | 3 | 16 | | |
LG | Wade Smith | 30 | 8 | 16 | 2 fumbles recovered | |
C | Chris Myers* | 30 | 6 | 16 | | |
RG | Mike Brisiel | 28 | 4 | 13 | | |
RT | Eric Winston | 28 | 5 | 16 | 1 fumble recovered | |
| Defensive Starters | | | | | |
LDE | J.J. Watt | 22 | Rook | 16 | 5.5 sacks, 0 interceptions, 2 fumbles recovered | |
NT | Shaun Cody | 28 | 6 | 16 | 1.0 sacks, 0 interceptions, 1 fumble recovered | |
RDE | Antonio Smith* | 30 | 7 | 16 | 6.5 sacks, 0 interceptions, 0 fumbles recovered | |
LOLB | Brooks Reed | 24 | Rook | 11 | 6.0 sacks, 0 interceptions, 2 fumbles recovered | |
LILB | Brian Cushing | 24 | 2 | 16 | 4.0 sacks, 2 interceptions, 0 fumbles recovered | |
RILB | DeMeco Ryans | 27 | 5 | 16 | | |
ROLB | Connor Barwin | 25 | 2 | 16 | 11.5 sacks, 0 interceptions, 0 fumbles recovered | |
LCB | Kareem Jackson | 23 | 1 | 13 | 0.0 sacks, 1 interception, 0 fumbles recovered | |
RCB | Johnathan Joseph* | 27 | 5 | 15 | 0.0 sacks, 4 interceptions, 0 fumbles recovered | |
SS | Glover Quin | 25 | 2 | 16 | 0.0 sacks, 0 interceptions, 1 fumble recovered | |
FS | Danieal Manning | 29 | 5 | 13 | 0.0 sacks, 2 interceptions, 0 fumbles recovered | |
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