All-Pros and Pro Bowlers
| Player | Pos | AP1 | First-team All-Pro Years | PB | Pro Bowl Years |
|---|---|---|---|---|---|
| J.J. Watt | DE | 5 | 2012, 2013, 2014, 2015, 2018 | 5 | 2012, 2013, 2014, 2015, 2018 |
| Andre Johnson | WR | 2 | 2008, 2009 | 7 | 2004, 2006, 2008, 2009, 2010, 2012, 2013 |
| DeAndre Hopkins | WR | 3 | 2017, 2018, 2019 | 4 | 2015, 2017, 2018, 2019 |
| Duane Brown | LT | 1 | 2012 | 4 | 2012, 2013, 2014, 2017 |
| Arian Foster | RB | 1 | 2010 | 4 | 2010, 2011, 2012, 2014 |
| Jerome Mathis | WR | 1 | 2005 | 1 | 2005 |
| Vonta Leach | RB | 1 | 2010 | 1 | 2010 |
| Deshaun Watson | QB | 0 | 3 | 2018, 2019, 2020 | |
| Jadeveon Clowney | DE | 0 | 3 | 2016, 2017, 2018 | |
| Johnathan Joseph | DB | 0 | 2 | 2011, 2012 | |
| Laremy Tunsil | OT | 0 | 2 | 2019, 2020 | |
| Matt Schaub | QB | 0 | 2 | 2009, 2012 | |
| DeMeco Ryans | LB | 0 | 2 | 2007, 2009 | |
| Mario Williams | DE | 0 | 2 | 2008, 2009 | |
| Owen Daniels | TE | 0 | 2 | 2008, 2012 | |
| Chris Myers | G | 0 | 2 | 2011, 2012 | |
| Brian Cushing | LB | 0 | 1 | 2009 | |
| Lamar Miller | RB | 0 | 1 | 2018 | |
| Aaron Glenn | DB | 0 | 1 | 2002 | |
| Wade Smith | T | 0 | 1 | 2012 | |
| Benardrick McKinney | ILB | 0 | 1 | 2018 | |
| Gary Walker | DT-DE | 0 | 1 | 2002 | |
| Antonio Smith | DE | 0 | 1 | 2011 | |
| Jon Weeks | C | 0 | 1 | 2015 |
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