| Single-season | Passing | Rushing | Receiving | Returns | Kicking | Scoring | |
| Career | Passing | Rushing | Receiving | Returns | Kicking | Scoring | Defense |
| Rk | From | To | G | Rec | Yds | TD | Lng | Fmb | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Andre Johnson | 2003 | 2009 | 95 | 540 | 7179 | 13.3 | 37 | 77 | 5.7 | 75.6 | 5 |
| 2 | Owen Daniels | 2006 | 2009 | 54 | 207 | 2501 | 12.1 | 15 | 44 | 3.8 | 46.3 | 7 |
| 3 | Jabar Gaffney | 2002 | 2005 | 64 | 171 | 2009 | 11.7 | 7 | 69 | 2.7 | 31.4 | 2 |
| 4 | Kevin Walter | 2006 | 2009 | 55 | 169 | 2187 | 12.9 | 13 | 61 | 3.1 | 39.8 | 1 |
| 5 | Domanick Williams | 2003 | 2005 | 40 | 154 | 1276 | 8.3 | 5 | 38 | 3.9 | 31.9 | 10 |
| 6 | Corey Bradford | 2002 | 2005 | 63 | 130 | 1992 | 15.3 | 18 | 81 | 2.1 | 31.6 | 0 |
| 7 | Billy Miller | 2002 | 2004 | 48 | 108 | 1146 | 10.6 | 7 | 42 | 2.3 | 23.9 | 1 |
| 8 | Steve Slaton | 2008 | 2009 | 25 | 82 | 703 | 8.6 | 4 | 46 | 3.3 | 28.1 | 10 |
| 9 | Eric Moulds | 2006 | 2006 | 16 | 57 | 557 | 9.8 | 1 | 29 | 3.6 | 34.8 | 1 |
| 10 | Vonta Leach | 2006 | 2009 | 50 | 55 | 355 | 6.5 | 3 | 22 | 1.1 | 7.1 | 2 |
| 11 | David Anderson | 2006 | 2009 | 42 | 50 | 579 | 11.6 | 3 | 65 | 1.2 | 13.8 | 1 |
| 12 | Andre' Davis | 2007 | 2009 | 33 | 50 | 824 | 16.5 | 3 | 53 | 1.5 | 25.0 | 1 |
| 13 | James Allen | 2002 | 2002 | 16 | 47 | 302 | 6.4 | 0 | 21 | 2.9 | 18.9 | 1 |
| 14 | Derick Armstrong | 2003 | 2005 | 35 | 45 | 605 | 13.4 | 2 | 44 | 1.3 | 17.3 | 0 |
| 15 | Jonathan Wells | 2002 | 2005 | 60 | 44 | 323 | 7.3 | 2 | 28 | 0.7 | 5.4 | 5 |
| 16 | Wali Lundy | 2006 | 2006 | 14 | 33 | 204 | 6.2 | 0 | 15 | 2.4 | 14.6 | 1 |
| 17 | Ron Dayne | 2006 | 2007 | 24 | 31 | 189 | 6.1 | 0 | 17 | 1.3 | 7.9 | 2 |
| 18 | Jacoby Jones | 2007 | 2009 | 39 | 31 | 468 | 15.1 | 3 | 45 | 0.8 | 12.0 | 8 |
| 19 | Jameel Cook | 2006 | 2007 | 27 | 26 | 147 | 5.7 | 0 | 15 | 1.0 | 5.4 | 2 |
| 20 | Ahman Green | 2007 | 2008 | 14 | 25 | 155 | 6.2 | 0 | 53 | 1.8 | 11.1 | 0 |
| 21 | Samkon Gado | 2006 | 2007 | 11 | 24 | 139 | 5.8 | 0 | 20 | 2.2 | 12.6 | 2 |
| 22 | Marcellus Rivers | 2005 | 2005 | 16 | 24 | 168 | 7.0 | 0 | 20 | 1.5 | 10.5 | 0 |
| 23 | Joel Dreessen | 2007 | 2009 | 35 | 22 | 199 | 9.0 | 2 | 28 | 0.6 | 5.7 | 1 |
| 24 | JaJuan Dawson | 2002 | 2002 | 14 | 21 | 286 | 13.6 | 0 | 28 | 1.5 | 20.4 | 1 |
| 25 | Jeb Putzier | 2006 | 2007 | 22 | 19 | 164 | 8.6 | 1 | 26 | 0.9 | 7.5 | 0 |
| 26 | Mark Bruener | 2004 | 2006 | 47 | 15 | 136 | 9.1 | 2 | 27 | 0.3 | 2.9 | 0 |
| 27 | Jabari Holloway | 2002 | 2003 | 26 | 15 | 157 | 10.5 | 0 | 33 | 0.6 | 6.0 | 0 |
| 28 | Darius Walker | 2007 | 2007 | 4 | 13 | 81 | 6.2 | 0 | 9 | 3.3 | 20.3 | 0 |
| 29 | Moran Norris | 2003 | 2005 | 44 | 12 | 57 | 4.8 | 1 | 11 | 0.3 | 1.3 | 0 |
| Rk | From | To | G | Rec | Yds | TD | Lng | Fmb | ||||
| 30 | Vernand Morency | 2005 | 2006 | 14 | 11 | 93 | 8.5 | 0 | 16 | 0.8 | 6.6 | 1 |
| 31 | Stacey Mack | 2003 | 2003 | 8 | 9 | 55 | 6.1 | 0 | 10 | 1.1 | 6.9 | 2 |
| 32 | Ryan Moats | 2008 | 2009 | 15 | 8 | 54 | 6.8 | 1 | 20 | 0.5 | 3.6 | 1 |
| 33 | Tony Hollings | 2003 | 2004 | 21 | 7 | 71 | 10.1 | 0 | 27 | 0.3 | 3.4 | 2 |
| 34 | Jarrod Baxter | 2002 | 2004 | 24 | 6 | 36 | 6.0 | 1 | 14 | 0.3 | 1.5 | 0 |
| 35 | Avion Black | 2002 | 2002 | 11 | 6 | 52 | 8.7 | 0 | 14 | 0.5 | 4.7 | 2 |
| 36 | Jerome Mathis | 2005 | 2007 | 15 | 6 | 80 | 13.3 | 1 | 34 | 0.4 | 5.3 | 3 |
| 37 | Chris Brown | 2009 | 2009 | 7 | 5 | 21 | 4.2 | 0 | 9 | 0.7 | 3.0 | 1 |
| 38 | Donovan Morgan | 2005 | 2005 | 3 | 4 | 42 | 10.5 | 0 | 14 | 1.3 | 14.0 | 0 |
| 39 | Edell Shepherd | 2006 | 2006 | 7 | 3 | 22 | 7.3 | 0 | 8 | 0.4 | 3.1 | 2 |
| 40 | Chris Taylor | 2006 | 2006 | 4 | 3 | 40 | 13.3 | 0 | 24 | 0.8 | 10.0 | 0 |
| 41 | James Casey | 2009 | 2009 | 3 | 2 | 14 | 7.0 | 0 | 7 | 0.7 | 4.7 | 0 |
| 42 | Adimchinobe Echemandu | 2007 | 2007 | 7 | 2 | 11 | 5.5 | 0 | 7 | 0.3 | 1.6 | 1 |
| 43 | Jermaine Lewis | 2002 | 2002 | 12 | 2 | 41 | 20.5 | 0 | 33 | 0.2 | 3.4 | 3 |
| 44 | Matt Murphy | 2005 | 2005 | 9 | 2 | 26 | 13.0 | 0 | 14 | 0.2 | 2.9 | 0 |
| 45 | Marcus Coleman | 2003 | 2003 | 15 | 1 | 6 | 6.0 | 0 | 6 | 0.1 | 0.4 | 0 |
| 46 | Atnaf Harris | 2002 | 2002 | 1 | 1 | 8 | 8.0 | 0 | 8 | 1.0 | 8.0 | 0 |
| 47 | Anthony Hill | 2009 | 2009 | 1 | 1 | 9 | 9.0 | 0 | 9 | 1.0 | 9.0 | 0 |
| 48 | Derrick Lewis | 2006 | 2006 | 4 | 1 | 5 | 5.0 | 0 | 5 | 0.3 | 1.3 | 0 |
| 49 | Dave Ragone | 2003 | 2003 | 2 | 1 | -5 | -5.0 | 0 | -5 | 0.5 | -2.5 | 4 |