1980 Week 4
| Sep 28, 1980 | ||
| Oakland Raiders | 7 | Final |
| Buffalo Bills | 24 | |
| PassYds | Ferguson-BUF | 175 |
| RushYds | Cribbs-BUF | 90 |
| RecYds | Chandler-OAK | 87 |
| Sep 28, 1980 | ||
| Houston Oilers | 13 | Final |
| Cincinnati Bengals | 10 | |
| PassYds | Stabler-HOU | 241 |
| RushYds | Johnson-CIN | 63 |
| RecYds | Carpenter-HOU | 47 |
| Sep 28, 1980 | ||
| Minnesota Vikings | 7 | Final |
| Detroit Lions | 27 | |
| PassYds | Kramer-MIN | 221 |
| RushYds | Sims-DET | 157 |
| RecYds | White-MIN | 76 |
| Sep 28, 1980 | ||
| Dallas Cowboys | 28 | Final |
| Green Bay Packers | 7 | |
| PassYds | White-DAL | 217 |
| RushYds | Dorsett-DAL | 77 |
| RecYds | Thompson-GNB | 77 |
| Sep 28, 1980 | ||
| New Orleans Saints | 16 | Final |
| Miami Dolphins | 21 | |
| PassYds | Griese-MIA | 241 |
| RushYds | Williams-MIA | 79 |
| RecYds | Nathan-MIA | 118 |
| Sep 28, 1980 | ||
| Los Angeles Rams | 28 | Final |
| New York Giants | 7 | |
| PassYds | Ferragamo-RAM | 215 |
| RushYds | Peacock-RAM | 85 |
| RecYds | Hill-RAM | 109 |
| Sep 28, 1980 | ||
| Chicago Bears | 3 | Final |
| Pittsburgh Steelers | 38 | |
| PassYds | Bradshaw-PIT | 217 |
| RushYds | Harris-PIT | 73 |
| RecYds | Smith-PIT | 131 |
| Sep 28, 1980 | ||
| Cleveland Browns | 34 | Final |
| Tampa Bay Buccaneers | 27 | |
| PassYds | Williams-TAM | 343 |
| RushYds | Pruitt-CLE | 48 |
| RecYds | Jones-TAM | 106 |
| Sep 28, 1980 | ||
| Philadelphia Eagles | 14 | Final |
| St. Louis Cardinals | 24 | |
| PassYds | Jaworski-PHI | 226 |
| RushYds | Anderson-STL | 151 |
| RecYds | Carmichael-PHI | 108 |
| Sep 28, 1980 | ||
| New York Jets | 21 | Final |
| Baltimore Colts | 35 | |
| PassYds | Jones-BAL | 275 |
| RushYds | Washington-BAL | 81 |
| RecYds | Jones-NYJ | 90 |
| Sep 28, 1980 | ||
| San Diego Chargers | 24 | Final |
| Kansas City Chiefs | 7 | |
| PassYds | Fouts-SDG | 194 |
| RushYds | Cappelletti-SDG | 51 |
| RecYds | Winslow-SDG | 74 |
| Sep 28, 1980 | ||
| Atlanta Falcons | 20 | Final |
| San Francisco 49ers | 17 | |
| PassYds | DeBerg-SFO | 345 |
| RushYds | Andrews-ATL | 98 |
| RecYds | Solomon-SFO | 132 |
| Sep 28, 1980 | ||
| Seattle Seahawks | 14 | Final |
| Washington Redskins | 0 | |
| PassYds | Theismann-WAS | 200 |
| RushYds | Jodat-SEA | 117 |
| RecYds | Thompson-WAS | 50 |
| Sep 29, 1980 | ||
| Denver Broncos | 14 | Final |
| New England Patriots | 23 | |
| PassYds | Grogan-NWE | 209 |
| RushYds | Armstrong-DEN | 80 |
| RecYds | Morgan-NWE | 83 |
1980 Week Summaries