1980 Week 5
| Oct 5, 1980 | ||
| Detroit Lions | 28 | Final |
| Atlanta Falcons | 43 | |
| PassYds | Danielson-DET | 348 |
| RushYds | Cain-ATL | 102 |
| RecYds | Thompson-DET | 129 |
| Oct 5, 1980 | ||
| Denver Broncos | 19 | Final |
| Cleveland Browns | 16 | |
| PassYds | Sipe-CLE | 258 |
| RushYds | Pruitt-CLE | 60 |
| RecYds | Rucker-CLE | 83 |
| Oct 5, 1980 | ||
| Cincinnati Bengals | 9 | Final |
| Green Bay Packers | 14 | |
| PassYds | Dickey-GNB | 203 |
| RushYds | Alexander-CIN | 52 |
| RecYds | Lofton-GNB | 114 |
| Oct 5, 1980 | ||
| Baltimore Colts | 30 | Final |
| Miami Dolphins | 17 | |
| PassYds | Jones-BAL | 282 |
| RushYds | Washington-BAL | 74 |
| RecYds | Carr-BAL | 87 |
| Oct 5, 1980 | ||
| Pittsburgh Steelers | 23 | Final |
| Minnesota Vikings | 17 | |
| PassYds | Bradshaw-PIT | 236 |
| RushYds | Harris-PIT | 102 |
| RecYds | Swann-PIT | 107 |
| Oct 5, 1980 | ||
| St. Louis Cardinals | 40 | Final |
| New Orleans Saints | 7 | |
| PassYds | Hart-STL | 113 |
| RushYds | Anderson-STL | 126 |
| RecYds | Williams-NOR | 28 |
| Oct 5, 1980 | ||
| New England Patriots | 21 | Final |
| New York Jets | 11 | |
| PassYds | Todd-NYJ | 252 |
| RushYds | Dierking-NYJ | 52 |
| RecYds | Jackson-NWE | 73 |
| Oct 5, 1980 | ||
| Seattle Seahawks | 26 | Final |
| Houston Oilers | 7 | |
| PassYds | Stabler-HOU | 174 |
| RushYds | Campbell-HOU | 50 |
| RecYds | McCullum-SEA | 80 |
| Oct 5, 1980 | ||
| Washington Redskins | 14 | Final |
| Philadelphia Eagles | 24 | |
| PassYds | Theismann-WAS | 232 |
| RushYds | Claitt-WAS | 58 |
| RecYds | Carmichael-PHI | 63 |
| Oct 5, 1980 | ||
| New York Giants | 3 | Final |
| Dallas Cowboys | 24 | |
| PassYds | White-DAL | 266 |
| RushYds | Taylor-NYG | 76 |
| RecYds | Hill-DAL | 88 |
| Oct 5, 1980 | ||
| Kansas City Chiefs | 31 | Final |
| Oakland Raiders | 17 | |
| PassYds | Plunkett-OAK | 238 |
| RushYds | McKnight-KAN | 64 |
| RecYds | Branch-OAK | 93 |
| Oct 5, 1980 | ||
| San Francisco 49ers | 26 | Final |
| Los Angeles Rams | 48 | |
| PassYds | Ferragamo-RAM | 304 |
| RushYds | Peacock-RAM | 114 |
| RecYds | Hofer-SFO | 91 |
| Oct 5, 1980 | ||
| Buffalo Bills | 26 | Final |
| San Diego Chargers | 24 | |
| PassYds | Fouts-SDG | 220 |
| RushYds | Cribbs-BUF | 87 |
| RecYds | Jefferson-SDG | 85 |
| Oct 6, 1980 | ||
| Tampa Bay Buccaneers | 0 | Final |
| Chicago Bears | 23 | |
| PassYds | Phipps-CHI | 110 |
| RushYds | Payton-CHI | 133 |
| RecYds | Jones-TAM | 62 |
1980 Week Summaries